LOCUS BC015945 2462 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens kelch-like ECH-associated protein 1, mRNA (cDNA clone
MGC:9454 IMAGE:3910857), complete cds.
ACCESSION BC015945
VERSION BC015945.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2462)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2462)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 15 Row: h Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 45269143.
FEATURES Location/Qualifiers
source 1..2462
/db_xref="H-InvDB:HIT000037418"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9454 IMAGE:3910857"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2462
/gene="KEAP1"
/gene_synonym="INrf2"
/gene_synonym="KIAA0132"
/gene_synonym="KLHL19"
/gene_synonym="MGC10630"
/gene_synonym="MGC1114"
/gene_synonym="MGC20887"
/gene_synonym="MGC4407"
/gene_synonym="MGC9454"
/db_xref="GeneID:9817"
/db_xref="HGNC:HGNC:23177"
/db_xref="MIM:606016"
CDS 42..1916
/gene="KEAP1"
/gene_synonym="INrf2"
/gene_synonym="KIAA0132"
/gene_synonym="KLHL19"
/gene_synonym="MGC10630"
/gene_synonym="MGC1114"
/gene_synonym="MGC20887"
/gene_synonym="MGC4407"
/gene_synonym="MGC9454"
/codon_start=1
/product="kelch-like ECH-associated protein 1"
/protein_id="AAH15945.1"
/db_xref="GeneID:9817"
/db_xref="HGNC:HGNC:23177"
/db_xref="MIM:606016"
/translation="MQPDPRPSGAGACCRFLPLQSQCPEGAGDAVMYASTECKAEVTP
SQHGNRTFSYTLEDHTKQAFGIMNELRLSQQLCDVTLQVKYQDAPAAQFMAHKVVLAS
SSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAV
MYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCVELHQRAREYIYMHFGEVAKQE
EFFNLSHCQLVTLISRDDLNVRCESEVFHACINWVKYDCEQRRFYVQALLRAVRCHSL
TPNFLQMQLQKCEILQSDSRCKDYLVKIFEELTLHKPTQVMPCRAPKVGRLIYTAGGY
FRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSA
LDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEW
HLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRS
GAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRI
YVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQQNCTC
"
BASE COUNT 535 a 704 c 754 g 469 t
ORIGIN
1 gagtgccaga ggtggtggtg ttgcttatct tctggaaccc catgcagcca gatcccaggc
61 ctagcggggc tggggcctgc tgccgattcc tgcccctgca gtcacagtgc cctgaggggg
121 caggggacgc ggtgatgtac gcctccactg agtgcaaggc ggaggtgacg ccctcccagc
181 atggcaaccg caccttcagc tacaccctgg aggatcatac caagcaggcc tttggcatca
241 tgaacgagct gcggctcagc cagcagctgt gtgacgtcac actgcaggtc aagtaccagg
301 atgcaccggc cgcccagttc atggcccaca aggtggtgct ggcctcatcc agccctgtct
361 tcaaggccat gttcaccaac gggctgcggg agcagggcat ggaggtggtg tccattgagg
421 gtatccaccc caaggtcatg gagcgcctca ttgaattcgc ctacacggcc tccatctcca
481 tgggcgagaa gtgtgtcctc cacgtcatga acggtgctgt catgtaccag atcgacagcg
541 ttgtccgtgc ctgcagtgac ttcctggtgc agcagctgga ccccagcaat gccatcggca
601 tcgccaactt cgctgagcag attggctgtg tggagttgca ccagcgtgcc cgggagtaca
661 tctacatgca ttttggggag gtggccaagc aagaggagtt cttcaacctg tcccactgcc
721 aactggtgac cctcatcagc cgggacgacc tgaacgtgcg ctgcgagtcc gaggtcttcc
781 acgcctgcat caactgggtc aagtacgact gcgaacagcg acggttctac gtccaggcgc
841 tgctgcgggc cgtgcgctgc cactcgttga cgccgaactt cctgcagatg cagctgcaga
901 agtgcgagat cctgcagtcc gactcccgct gcaaggacta cctggtcaag atcttcgagg
961 agctcaccct gcacaagccc acgcaggtga tgccctgccg ggcgcccaag gtgggccgcc
1021 tgatctacac cgcgggcggc tacttccgac agtcgctcag ctacctggag gcttacaacc
1081 ccagtgacgg cacctggctc cggttggcgg acctgcaggt gccgcggagc ggcctggccg
1141 gctgcgtggt gggcgggctg ttgtacgccg tgggcggcag gaacaactcg cccgacggca
1201 acaccgactc cagcgccctg gactgttaca accccatgac caatcagtgg tcgccctgcg
1261 cccccatgag cgtgccccgt aaccgcatcg gggtgggggt catcgatggc cacatctatg
1321 ccgtcggcgg ctcccacggc tgcatccacc acaacagtgt ggagaggtat gagccagagc
1381 gggatgagtg gcacttggtg gccccaatgc tgacacgaag gatcggggtg ggcgtggctg
1441 tcctcaatcg tctcctttat gccgtggggg gctttgacgg gacaaaccgc cttaattcag
1501 ctgagtgtta ctacccagag aggaacgagt ggcgaatgat cacagcaatg aacaccatcc
1561 gaagcggggc aggcgtctgc gtcctgcaca actgtatcta tgctgctggg ggctatgatg
1621 gtcaggacca gctgaacagc gtggagcgct acgatgtgga aacagagacg tggactttcg
1681 tagcccccat gaagcaccgg cgaagtgccc tggggatcac tgtccaccag gggagaatct
1741 acgtccttgg aggctatgat ggtcacacgt tcctggacag tgtggagtgt tacgacccag
1801 atacagacac ctggagcgag gtgacccgaa tgacatcggg ccggagtggg gtgggcgtgg
1861 ctgtcaccat ggagccctgc cggaagcaga ttgaccagca gaactgtacc tgttgaggca
1921 cttttgtttc ttgggcaaaa atacagtcca atggggagta tcattgtttt tgtacaaaaa
1981 ccgggactaa aagaaaagac agcactgcaa ataacccatc ttccgggaag ggaggccagg
2041 atgcctcagt gttaaaatga catctcaaaa gaagtccaaa gcgggaatca tgtgcccctc
2101 agcggagccc cgggagtgtc caagacagcc tggctgggaa agggggtgtg gaaagagcag
2161 gcttccagga gagaggcccc caaaccctct ggccgggtaa taggcctggg tcccactcac
2221 ccatgccggc agctgtcacc atgtgattta ttcttggata cctgggaggg ggccaatggg
2281 ggcctcaggg ggaggccccc tctggaaatg tggttcccag ggatgggcct gtacatagaa
2341 gccaccggat ggcacttccc caccggatgg acagttattt tgttgataag taaccctgta
2401 attttccaag gaaaataaag aacagactaa ctagtgtctt tcaccctgaa aaaaaaaaaa
2461 aa
//