LOCUS BC015749 2155 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens syntaxin binding protein 1, mRNA (cDNA clone MGC:23061
IMAGE:4868854), complete cds.
ACCESSION BC015749
VERSION BC015749.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2155)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2155)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 34 Row: l Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4507296.
FEATURES Location/Qualifiers
source 1..2155
/db_xref="H-InvDB:HIT000037295"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23061 IMAGE:4868854"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2155
/gene="STXBP1"
/gene_synonym="hUNC18"
/gene_synonym="MUNC18-1"
/gene_synonym="rbSec1"
/gene_synonym="UNC18"
/db_xref="GeneID:6812"
/db_xref="HGNC:HGNC:11444"
/db_xref="MIM:602926"
CDS 114..1898
/gene="STXBP1"
/gene_synonym="hUNC18"
/gene_synonym="MUNC18-1"
/gene_synonym="rbSec1"
/gene_synonym="UNC18"
/codon_start=1
/product="syntaxin binding protein 1"
/protein_id="AAH15749.1"
/db_xref="GeneID:6812"
/db_xref="HGNC:HGNC:11444"
/db_xref="MIM:602926"
/translation="MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSC
CKMTDIMTEGITIVEDINKRREPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAA
HVFFTDSCPDALFNELVKSRAAKVIKTLTEINIAFLPYESQVYSLDSADSFQSFYSPH
KAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPT
MGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDLLPIENDVYKYETSGIGEARV
KEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKKM
PQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVP
ILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLGVPI
VTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSA
SFSTTAVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVL
IGSTHILTPQKLLDTLKKLNKTDEEISS"
BASE COUNT 594 a 600 c 543 g 418 t
ORIGIN
1 gcggctgcgg ggcggagagc tgcggctggc ccagcgcgcc cacctgagga ggcggcgggg
61 tccgcaggcg tcgcgggacg aggagatcgg agccgggaga ctcgcgcagc gccatggccc
121 ccattggcct caaagctgtt gtcggagaga agattatgca tgatgtgata aagaaggtca
181 agaagaaggg ggaatggaag gtgctggtgg tggatcagtt aagcatgagg atgctgtcct
241 cctgctgcaa gatgacagac atcatgaccg agggcataac gattgtggaa gatatcaata
301 agcgcagaga gccgctcccc agcctggagg ctgtgtatct catcactcca tccgagaagt
361 ccgtccactc tctcatcagt gactttaagg acccgccgac tgctaaatac cgggctgcac
421 acgtcttctt cactgactct tgtccagatg ccctgtttaa tgaactggta aaatcccgag
481 cagccaaagt catcaaaact ctgacggaaa tcaatattgc atttctcccg tatgaatccc
541 aggtctattc cttggactct gctgactctt tccaaagctt ctacagtccc cacaaggctc
601 agatgaagaa tcctatactg gagcgcctgg cagagcagat cgcgaccctt tgtgccaccc
661 tgaaggagta cccggctgtg cggtatcggg gggaatacaa ggacaatgcc ctgctggctc
721 agctaatcca ggacaagctc gatgcctata aagctgatga tccaacaatg ggggagggcc
781 cagacaaggc acgctcccag ctcctgatcc tggatcgagg ctttgacccc agctcccctg
841 tgctccatga attgactttt caggctatga gttatgatct gctgcctatc gaaaatgatg
901 tatacaagta tgagaccagc ggcatcgggg aggcacgggt gaaggaggtg ctcctggacg
961 aggacgacga cctgtggata gcactgcgcc acaagcacat cgcagaggtg tcccaggaag
1021 tcacccggtc tctgaaagat ttttcttcta gcaagagaat gaatactgga gagaagacca
1081 ccatgcggga cctgtcccag atgctgaaga agatgcctca gtaccagaaa gagctcagca
1141 agtactccac ccacctgcac cttgctgagg actgtatgaa gcattaccaa ggcaccgtag
1201 acaaactctg ccgagtggag caggacctgg ccatgggcac agatgctgag ggagagaaga
1261 tcaaggaccc tatgcgagcc atcgtcccca ttctgctgga tgccaatgtc agcacttatg
1321 acaaaatccg catcatcctt ctctacatct ttttgaagaa tggcatcacg gaggaaaacc
1381 tgaacaaact gatccagcac gcccagatac ccccggagga tagtgagatc atcaccaaca
1441 tggctcacct cggcgtgccc atcgtcaccg attccacgct gcgtcgccgg agcaagccgg
1501 agcggaagga acgcatcagc gagcagacct accagctctc acggtggact ccgattatca
1561 aggacatcat ggaggacact attgaggaca aacttgacac caaacactac ccttatatct
1621 ctacccgttc ctctgcctcc ttcagcacca ccgccgtcag cgcccgctat gggcactggc
1681 ataagaacaa ggccccaggc gagtaccgca gtggcccccg cctcatcatt ttcatccttg
1741 ggggtgtgag cctgaatgag atgcgctgcg cctacgaggt gacccaggcc aacggaaagt
1801 gggaggtgct gataggatcc acacacatcc tcaccccaca gaaactgctg gacacactga
1861 agaaactgaa taaaacagat gaagaaataa gcagttaaaa aaataagtcg cccctccaaa
1921 acacgccccc atcccacagc gctccgcagc ttcccaccac cgcccgcctc agttcctttg
1981 cgtctgttgc ctccccagcc ctgcacgccc tggctggcac tgttgccgct gcattctcgt
2041 gttcagtgat gccctcttct tgtttgaaac aaaagaaaat aatgcattgt gttttttaaa
2101 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa
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