LOCUS BC015687 1711 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens folliculin, mRNA (cDNA clone MGC:23445 IMAGE:4684974),
complete cds.
ACCESSION BC015687
VERSION BC015687.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1711)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1711)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC015687.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 33 Row: j Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 51317378.
FEATURES Location/Qualifiers
source 1..1711
/db_xref="H-InvDB:HIT000037257"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23445 IMAGE:4684974"
/tissue_type="Skin, melanoma, amelanotic"
/clone_lib="NIH_MGC_41"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1711
/gene="FLCN"
/gene_synonym="BHD"
/gene_synonym="FLCL"
/gene_synonym="MGC17998"
/gene_synonym="MGC23445"
/db_xref="GeneID:201163"
/db_xref="HGNC:HGNC:27310"
/db_xref="MIM:607273"
CDS 456..1484
/gene="FLCN"
/gene_synonym="BHD"
/gene_synonym="FLCL"
/gene_synonym="MGC17998"
/gene_synonym="MGC23445"
/codon_start=1
/product="folliculin"
/protein_id="AAH15687.1"
/db_xref="GeneID:201163"
/db_xref="HGNC:HGNC:27310"
/db_xref="MIM:607273"
/translation="MNAIVALCHFCELHGPRTLFCTEVLHAPLPQGDGNEDSPGQGEQ
AEEEEGGIQMNSRMRAHSPAEGASVESSSPGPKKSDMCEGCRSLAAGHPGYISHDKET
SIKYVSHQHPSHPQLFSIVRQACVRSLSCEVCPGREGPIFFGDEQHGFVFSHTFFIKD
SLARGFQRWYSIITIMMDRIYLINSWPFLLGKVRGIIDELQGKALKVFEAEQFGCPQR
AQRMNTAFTPFLHQRNGNAARSLTSLTSDDNLWACLHTSFAWLLKACGSRLTEKLLEG
APTEDTLVQMEKLAGEAGVLLPGPWPGWPWGGTSCLLSWQESLREGNAALNQPRTSLR
EAHPPISV"
BASE COUNT 339 a 499 c 529 g 344 t
ORIGIN
1 ggtcgctcct ggttctgcca gctcccctga gagcctgaac ccgggcttga gagcctcgcc
61 accccgggtg acatccctgc cgtgggcttg ggggctctgg gtgtgattcc gccggtccgg
121 gtcccgcagc gaccacctac ccagcgcagt caggggtggg gctgggaccc agagcgggac
181 cccggctgcc gagtccaggt gtcccgcggg cctcgatttg gggagcagaa aacgccaggt
241 cttcaagggt gtctgccacc accatgcctg acccatttgg cagcagcctc gtgtgtggtg
301 gtctggtgtg gacggtggaa gcgtgattct gctgagtgtc agtgtgacca ctcgtgctca
361 gccgtatctc agcaggagga caggtgccgg agcagctcgt gcagctaagc agccaactgc
421 agaaacgtca ggcctgttgc agtctccaag gcaccatgaa tgccatcgtg gctctctgcc
481 acttctgcga gctccacggc ccccgcactc tcttctgcac ggaggtgctg cacgccccac
541 ttcctcaagg ggatgggaat gaggacagtc ctggccaggg tgagcaggcg gaagaagagg
601 aaggtggcat tcagatgaac agtcggatgc gtgcgcacag ccccgcagag ggggccagcg
661 tcgagtccag cagcccgggg cccaaaaagt cggacatgtg cgagggctgc cggtcacttg
721 ctgcagggca cccgggatat atcagccatg ataaagagac ctccattaaa tacgtcagcc
781 accagcaccc cagccacccc cagctcttca gcattgtccg ccaggcctgt gtccggagcc
841 tgagctgtga ggtctgccct ggccgtgaag gccccatctt cttcggagat gagcagcacg
901 gctttgtgtt cagccacacc ttcttcatca aggacagcct ggccaggggc ttccagcgct
961 ggtacagcat catcaccatc atgatggacc ggatctacct catcaactcc tggcccttcc
1021 tgctggggaa ggtccgggga atcatcgatg agctccaggg caaggcgctc aaggtgtttg
1081 aggcagagca gtttggatgc ccacagcgtg ctcagaggat gaacacagcc ttcacgccat
1141 tcctacacca gaggaacggc aacgccgccc gctcgctgac atcgctgaca agtgatgaca
1201 acctgtgggc gtgcctgcac acctcctttg cctggctcct gaaggcgtgt ggcagccggc
1261 tgaccgagaa gctcctggaa ggtgctccga ccgaggatac cttggtccag atggagaagc
1321 tcgctggtga ggcaggggtg ctgttgccgg ggccttggcc cggatggccg tggggcggta
1381 ccagctgtct gctctcctgg caggaatcgc tgagggaggg aaacgcggct ctgaatcagc
1441 ccagaacgag ccttcgggaa gctcaccctc cgatctcggt gtgattgttg tgattgttgt
1501 gatttcctgt ctcgtttgcc ttgaccgcca tgtgaaagaa tctgttcccc agctaggtgg
1561 ggaaaattca caggtgggct gtctgtagag agaactggct gattaaaggc ttctcgtccc
1621 gattttgtga tagccaagtg cttggcctgg tcgacggtct ttgctccttt acaaataaag
1681 tgttctgttt caaaaaaaaa aaaaaaaaaa a
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