LOCUS BC015665 1207 bp mRNA linear HUM 06-OCT-2005
DEFINITION Homo sapiens LATS, large tumor suppressor, homolog 1 (Drosophila),
mRNA (cDNA clone IMAGE:4550430), complete cds.
ACCESSION BC015665
VERSION BC015665.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1207)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1207)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC015665.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 33 Row: b Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 10862687
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1207
/db_xref="H-InvDB:HIT000050632"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4550430"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_18"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1207
/gene="LATS1"
/gene_synonym="WARTS"
/gene_synonym="wts"
/db_xref="GeneID:9113"
/db_xref="HGNC:HGNC:6514"
/db_xref="IMGT/GENE-DB:6514"
/db_xref="MIM:603473"
CDS 317..724
/gene="LATS1"
/gene_synonym="WARTS"
/gene_synonym="wts"
/codon_start=1
/product="LATS1 protein"
/protein_id="AAH15665.1"
/db_xref="GeneID:9113"
/db_xref="HGNC:HGNC:6514"
/db_xref="IMGT/GENE-DB:6514"
/db_xref="MIM:603473"
/translation="MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKP
SDAAKAEHNMSKMSTEDPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVN
PQMLQDLQAAGFDEEDHLSVACSPISLTKPFLI"
BASE COUNT 413 a 268 c 246 g 280 t
ORIGIN
1 gagccaggtc ctcacgaccc ctgggacggg ccgcgctggc ccgcggcagc ccccccgttc
61 gtctccccgc tctgccccac cagggatact tggggttgct gggacggact ctggccgcct
121 cagcgtccgc cctcaggccc gtggccgctg tccaggagct ctgctctccc ctccagagtt
181 aattatttat attgtaaaga attttaacag tcctggggac ttccttgaag gatcattttc
241 acttttgctc agaagaaagc tctggatcta tcaaataaag aagtccttcg tgtgggctac
301 atatatagat gttttcatga agaggagtga aaagccagaa ggatatagac aaatgaggcc
361 taagaccttt cctgccagta actatactgt cagtagccgg caaatgttac aagaaattcg
421 ggaatccctt aggaatttat ctaaaccatc tgatgctgct aaggctgagc ataacatgag
481 taaaatgtca accgaagatc ctcgacaagt cagaaatcca cccaaatttg ggacgcatca
541 taaagccttg caggaaattc gaaactctct gcttccattt gcaaatgaaa caaattcttc
601 tcggagtact tcagaagtta atccacaaat gcttcaagac ttgcaagctg ctggatttga
661 tgaggaggat catctgtcag tagcctgttc acccattagt cttactaagc catttctcat
721 ttaaaaatgt cgtttgaaat actgaatcct ctaggacaag atatggttat acaagctctt
781 cagaaaacta acaacagaag tatagaagca gcaattgaat tcattagtaa aatgagttac
841 caagatcctc gacgagagca gatggctgca gcagctgcca gacctattaa tgccagcatg
901 aaaccaggga atgtgcagca atcagttaac cgcaaacaga gctggaaagg ttctaaagaa
961 tccttagttc ctcagaggca tggcccgcca ctaggagaaa gtgtggccta tcattctgag
1021 agtcccaact cacagacaga tgtaggaaga cctttgtctg gatctggtat atcagcattt
1081 gttcaagctc accccaaagt attaaaagta gctttgtaat tcaaaaaaaa aaaaaaaaaa
1141 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1201 aaaaaaa
//