LOCUS BC015610 3543 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens nuclear receptor subfamily 3, group C, member 1
(glucocorticoid receptor), mRNA (cDNA clone MGC:23072
IMAGE:4810424), complete cds.
ACCESSION BC015610
VERSION BC015610.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3543)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3543)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC015610.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 33 Row: m Column: 1
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 66528192.
FEATURES Location/Qualifiers
source 1..3543
/db_xref="H-InvDB:HIT000037213"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23072 IMAGE:4810424"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3543
/gene="NR3C1"
/gene_synonym="GCCR"
/gene_synonym="GCR"
/gene_synonym="GR"
/db_xref="GeneID:2908"
/db_xref="HGNC:HGNC:7978"
/db_xref="MIM:138040"
CDS 441..2774
/gene="NR3C1"
/gene_synonym="GCCR"
/gene_synonym="GCR"
/gene_synonym="GR"
/codon_start=1
/product="nuclear receptor subfamily 3, group C, member 1
(glucocorticoid receptor)"
/protein_id="AAH15610.1"
/db_xref="GeneID:2908"
/db_xref="HGNC:HGNC:7978"
/db_xref="MIM:138040"
/translation="MDSKESLTPGREENPSSVLAQERGDVMDFYKTLRGGATVKVSAS
SPSLAVASQSDSKQRRLLVDFPKGSVSNAQQPDLSKAVSLSMGLYMGETETKVMGNDL
GFPQQGQISLSSGETDLKLLEESIANLNRSTSVPENPKSSASTAVSAAPTEKEFPKTH
SDVSSEQQHLKGQTGTNGGNVKLYTTDQSTFDILQDLEFSSGSPGKETNESPWRSDLL
IDENCLLSPLAGEDDSFLLEGNSNEDCKPLILPDTKPKIKDNGDLVLSSPSNVTLPQV
KTEKEDFIELCTPGVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHY
DMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNG
YSSPSMRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVE
GQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVS
QETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNML
GGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFA
PDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKS
QELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTF
LDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK"
BASE COUNT 1020 a 773 c 797 g 953 t
ORIGIN
1 ctgccctttc gcgtgtccgc gctctcttcc ctccgccgcc gcctcctcca ttttgcgagc
61 tcgtgtctgt gacgggagcc cgagtcaccg cctgcccgtc ggggacggat tctgtgggtg
121 gaaggagacg ccgcagccgg agcggccgaa gcagctggga ccgggacggg gcacgcgcgc
181 ccggaagccc cgacccgcgg agcccggcgc ggggcggagg gctggcttgt cagctgggca
241 atgggagact ttcttaaata ggggctctcc ccccacccat ggagaaaggg gcggctgttt
301 acttcctttt tttagaaaaa aaaaatatat ttccctcctg ctccttctgc gttcacaagc
361 taagttgttt atctcggctg cggcgggaac tgcggacggt ggcgggcgag cggctcctct
421 gccagagttg atattcactg atggactcca aagaatcatt aactcctggt agagaagaaa
481 accccagcag tgtgcttgct caggagaggg gagatgtgat ggacttctat aaaaccctaa
541 gaggaggagc tactgtgaag gtttctgcgt cttcaccctc actggctgtc gcttctcaat
601 cagactccaa gcagcgaaga cttttggttg attttccaaa aggctcagta agcaatgcgc
661 agcagccaga tctgtccaaa gcagtttcac tctcaatggg actgtatatg ggagagacag
721 aaacaaaagt gatgggaaat gacctgggat tcccacagca gggccaaatc agcctttcct
781 cgggggaaac agacttaaag cttttggaag aaagcattgc aaacctcaat aggtcgacca
841 gtgttccaga gaaccccaag agttcagcat ccactgctgt gtctgctgcc cccacagaga
901 aggagtttcc aaaaactcac tctgatgtat cttcagaaca gcaacatttg aagggccaga
961 ctggcaccaa cggtggcaat gtgaaattgt ataccacaga ccaaagcacc tttgacattt
1021 tgcaggattt ggagttttct tctgggtccc caggtaaaga gacgaatgag agtccttgga
1081 gatcagacct gttgatagat gaaaactgtt tgctttctcc tctggcggga gaagacgatt
1141 cattcctttt ggaaggaaac tcgaatgagg actgcaagcc tctcatttta ccggacacta
1201 aacccaaaat taaggataat ggagatctgg ttttgtcaag ccccagtaat gtaacactgc
1261 cccaagtgaa aacagaaaaa gaagatttca tcgaactctg cacccctggg gtaattaagc
1321 aagagaaact gggcacagtt tactgtcagg caagctttcc tggagcaaat ataattggta
1381 ataaaatgtc tgccatttct gttcatggtg tgagtacctc tggaggacag atgtaccact
1441 atgacatgaa tacagcatcc ctttctcaac agcaggatca gaagcctatt tttaatgtca
1501 ttccaccaat tcccgttggt tccgaaaatt ggaataggtg ccaaggatct ggagatgaca
1561 acttgacttc tctggggact ctgaacttcc ctggtcgaac agttttttct aatggctatt
1621 caagccccag catgagacca gatgtaagct ctcctccatc cagctcctca acagcaacaa
1681 caggaccacc tcccaaactc tgcctggtgt gctctgatga agcttcagga tgtcattatg
1741 gagtcttaac ttgtggaagc tgtaaagttt tcttcaaaag agcagtggaa ggacagcaca
1801 attacctatg tgctggaagg aatgattgca tcatcgataa aattcgaaga aaaaactgcc
1861 cagcatgccg ctatcgaaaa tgtcttcagg ctggaatgaa cctggaagct cgaaaaacaa
1921 agaaaaaaat aaaaggaatt cagcaggcca ctacaggagt ctcacaagaa acctctgaaa
1981 atcctggtaa caaaacaata gttcctgcaa cgttaccaca actcacccct accctggtgt
2041 cactgttgga ggttattgaa cctgaagtgt tatatgcagg atatgatagc tctgttccag
2101 actcaacttg gaggatcatg actacgctca acatgttagg agggcggcaa gtgattgcag
2161 cagtgaaatg ggcaaaggca ataccaggtt tcaggaactt acacctggat gaccaaatga
2221 ccctactgca gtactcctgg atgtttctta tggcatttgc tctggggtgg agatcatata
2281 gacaatcaag tgcaaacctg ctgtgttttg ctcctgatct gattattaat gagcagagaa
2341 tgactctacc ctgcatgtac gaccaatgta aacacatgct gtatgtttcc tctgagttac
2401 acaggcttca ggtatcttat gaagagtatc tctgtatgaa aaccttactg cttctctctt
2461 cagttcctaa ggacggtctg aagagccaag agctatttga tgaaattaga atgacctaca
2521 tcaaagagct aggaaaagcc attgtcaaga gggaaggaaa ctccagccag aactggcagc
2581 ggttttatca actgacaaaa ctcttggatt ctatgcatga agtggttgaa aatctcctta
2641 actattgctt ccaaacattt ttggataaga ccatgagtat tgaattcccc gagatgttag
2701 ctgaaatcat caccaatcag ataccaaaat attcaaatgg aaatatcaaa aaacttctgt
2761 ttcatcaaaa gtgactgcct taataagaat ggttgcctta aagaaagtcg aattaatagc
2821 ttttattgta taaactatca gtttgtcctg tagaggtttt gttgttttat tttttattgt
2881 tttcatctgt tgttttgttt taaatacgca ctacatgtgg tttatagagg gccaagactt
2941 ggcaacagaa gcagttgagt cgtcatcact tttcagtgat gggagagtag atggtgaaat
3001 ttattagtta atatatccca gaaattagaa accttaatat gtggacgtaa tctccacagt
3061 caaagaagga tggcacctaa accaccagtg cccaaagtct gtgtgatgaa ctttctcttc
3121 atactttttt tcacagttgg ctggatgaaa ttttctagac tttctgttgg tgtatccccc
3181 ccctgtatag ttaggatagc atttttgatt tatgcatgga aacctgaaaa aaagtttaca
3241 agtgtatatc agaaaaggga agttgtgcct tttatagcta ttactgtctg gttttaacaa
3301 tttcctttat atttagtgaa ctacgcttgc tcattttttc ttacataatt ttttattcaa
3361 gttattgtac agctgtttaa gatgggcagc tagttcgtag ctttcccaaa taaactctaa
3421 acattaatca atcatctgtg tgaaaatggg ttggtgcttc taacctgatg gcacttagct
3481 atcagaagac cacaaaaatt gactcaaatc tccagtattc ttgtcaaaaa aaaaaaaaaa
3541 aaa
//