LOCUS BC015474 2344 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens tyrosyl-DNA phosphodiesterase 1, mRNA (cDNA clone
MGC:8796 IMAGE:3900062), complete cds.
ACCESSION BC015474
VERSION BC015474.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2344)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2344)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 14 Row: l Column: 4.
FEATURES Location/Qualifiers
source 1..2344
/db_xref="H-InvDB:HIT000037131"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8796 IMAGE:3900062"
/tissue_type="Pancreas, epithelioid carcinoma"
/clone_lib="NIH_MGC_70"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2344
/gene="TDP1"
/gene_synonym="FLJ11090"
/db_xref="GeneID:55775"
/db_xref="HGNC:HGNC:18884"
/db_xref="MIM:607198"
CDS 251..2077
/gene="TDP1"
/gene_synonym="FLJ11090"
/codon_start=1
/product="tyrosyl-DNA phosphodiesterase 1"
/protein_id="AAH15474.1"
/db_xref="GeneID:55775"
/db_xref="HGNC:HGNC:18884"
/db_xref="MIM:607198"
/translation="MSQEGDYGRWTISSSDESEEEKPKPDKPSTSSLLCARQGAANEP
RYTCSEAQKAAHKRKISPVKFSNTDSVLPPKRQKSGSQEDLGWCLSSSDDELQPEMPQ
KQAEKVVIKKEKDISAPNDGTAQRTENHGAPACHRLKEEEDEYETSGEGQDIWDMLDK
GNPFQFYLTRVSGVKPKYNSGALHIKDILSPLFGTLVSSAQFNYCFDVDWLVKQYPPE
FRKKPILLVHGDKREAKAHLHAQAKPYENISLCQAKLDIAFGTHHTKMMLLLYEEGLR
VVIHTSNLIHADWHQKTQGIWLSPLYPRIADGTHKSGESPTHFKADLISYLMAYNAPS
LKEWIDVIHKHDLSETNVYLIGSTPGRFQGSQKDNWGHFRLKKLLKDHASSMPNAESW
PVVGQFSSVGSLGADESKWLCSEFKESMLTLGKESKTPGKSSVPLYLIYPSVENVRTS
LEGYPAGGSLPYSIQTAEKQNWLHSYFHKWSAETSGRSNAMPHIKTYMRPSPDFSKIA
WFLVTSANLSKAAWGALEKNGTQLMIRSYELGVLFLPSAFGLDSFKVKQKFFAGSQEP
MATFPVPYDLPPELYGSKDRPWIWNIPYVKAPDTHGNMWVPS"
BASE COUNT 707 a 535 c 542 g 560 t
ORIGIN
1 gttggttctg tgcgcctcag agttggagca cacagctgta ttaaaaaggc aaatcgaagg
61 ccgggcgcgg tgactcacgc ctgtcatcct agcactttgg gaggccgagg cggctgaatc
121 acttgaggtt aggagtttga gatcagcccg ggcaacatgg tgaaaccccg tctctacaaa
181 aatagaaaaa ttagccgagc gtgatggtgg atgcctgtaa tcctagctcc tcgggaggct
241 aaggagtata atgtctcagg aaggcgatta tgggaggtgg accatatcta gtagtgatga
301 aagtgaggaa gaaaagccaa aaccagacaa gccatctacc tcttctcttc tctgtgccag
361 gcaaggagca gcaaatgagc ccaggtacac ctgttccgag gcccagaaag ctgcacacaa
421 gaggaaaata tcacctgtga aattcagcaa tacagattca gttttacctc ccaaaaggca
481 gaaaagcggt tcccaggagg acctcggctg gtgtctgtcc agcagtgatg atgagctgca
541 accagaaatg ccgcagaagc aggctgagaa agtggtgatc aaaaaggaga aagacatctc
601 tgctcccaat gacggcactg cccaaagaac tgaaaatcat ggcgctcccg cctgccacag
661 gctcaaagag gaggaagacg agtatgagac atcaggggag ggccaggaca tttgggacat
721 gctggataaa gggaacccct tccagtttta cctcactaga gtctctggag ttaagccaaa
781 gtataactct ggagccctcc acatcaagga tattttatct cctttatttg ggacgcttgt
841 ttcttcagct cagtttaact actgctttga cgtggactgg ctcgtaaaac agtatccacc
901 agagttcagg aagaagccaa tcctgcttgt gcatggtgat aagcgagagg ctaaggctca
961 cctccatgcc caggccaagc cttacgagaa catctctctc tgccaggcaa agttggatat
1021 tgcgtttgga acacaccaca cgaaaatgat gctgctgctc tatgaagaag gcctccgggt
1081 tgtcatacac acctccaacc tcatccatgc tgactggcac cagaaaactc aaggaatatg
1141 gttgagcccc ttatacccac gaattgctga tggaacccac aaatctggag agtcgccaac
1201 acattttaaa gctgatctca tcagttactt gatggcttat aatgcccctt ctctcaagga
1261 gtggatagat gtcattcaca agcacgatct ctctgaaaca aatgtttatc ttattggttc
1321 aaccccagga cgctttcaag gaagtcaaaa agataattgg ggacatttta gacttaagaa
1381 gcttctgaaa gaccatgcct catccatgcc taacgcagag tcctggcctg tcgtaggtca
1441 gttttcaagc gttggctcct tgggagccga tgaatcaaag tggttatgtt ctgagtttaa
1501 agagagcatg ctgacactgg ggaaggaaag caagactcca ggaaaaagct ctgttcctct
1561 ttacttgatc tatccttctg tggaaaatgt gcggaccagt ttagaaggat atcctgctgg
1621 gggctctctt ccctatagca tccagacagc tgaaaaacag aattggctgc attcctattt
1681 tcacaaatgg tcagctgaga cttctggccg cagcaatgcc atgccacata ttaagacata
1741 tatgaggcct tctccagact tcagtaaaat tgcttggttc cttgtcacaa gcgcaaatct
1801 gtccaaggct gcctggggag cattggagaa gaatggcacc cagctgatga tccgctccta
1861 cgagctcggg gtccttttcc tcccttcagc atttggtcta gacagtttca aagtgaaaca
1921 gaagttcttc gctggcagcc aggagccaat ggccaccttt cctgtgccat atgatttgcc
1981 tccagaactg tatggaagta aagatcggcc atggatatgg aacattcctt atgtcaaagc
2041 accggatacg catgggaaca tgtgggtgcc ctcctgagaa tcttgaggca ctgtgaaatt
2101 taagtgtaag acattgagcc acaaacatgg aatctcttct ttgtactgga tgtccacttc
2161 ccttaaagtc ttatttgcac ccttacaaaa tctttccaaa ggtcactctt atgaatggat
2221 gttggttata cttttaatgg acattaacat tcctaataaa gtattagttt cttaaaaaaa
2281 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2341 aaaa
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