LOCUS BC015231 3486 bp mRNA linear HUM 06-JUN-2005
DEFINITION Homo sapiens pleckstrin homology domain containing, family G (with
RhoGef domain) member 5, mRNA (cDNA clone MGC:17838 IMAGE:3900065),
complete cds.
ACCESSION BC015231
VERSION BC015231.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3486)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3486)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 14 Row: l Column: 3.
FEATURES Location/Qualifiers
source 1..3486
/db_xref="H-InvDB:HIT000037062"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17838 IMAGE:3900065"
/tissue_type="Pancreas, epithelioid carcinoma"
/clone_lib="NIH_MGC_70"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3486
/gene="PLEKHG5"
/gene_synonym="KIAA0720"
/db_xref="GeneID:57449"
CDS 214..3006
/gene="PLEKHG5"
/gene_synonym="KIAA0720"
/codon_start=1
/product="PLEKHG5 protein"
/protein_id="AAH15231.1"
/db_xref="GeneID:57449"
/translation="MHYDGHVRFDLPPQGSVLARNVSTRSCPPRTSPAVDLEEEEEES
SVDGKGDRKSTGLKLSKKKARRRHTDDPSKECFTLKFDLNVDIETEIVPAMKKKSLGE
VLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQG
MKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRRRKNMSEFLGEASIPGQ
EPPTPSSCSLPSGSSGSTNTGDSWKNRAASRFSGFFSSGPSTSAFGREVDKMEQLEGK
LHTYSLFGLPRLPRGLRFDHDSWEEEYDEDEDEDNACLRLEDSWRELIDGHEKLTRRQ
CHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQ
LHRRLWASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMR
GLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAK
EAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFL
HLDLTAPIPGASPEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERT
RVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNA
QNQLQQLRAQEPPGSQQPLQSLEEEEDEQEEEEEEEEEEEEGEDSGTSAASSPTIMRK
SSGSPDSQHCASDGSTETLAMVVVEPGDTLSSPEFDSGPFSSQSDETSLSTTASSATP
TSELLPLGPVDGRSCSMDSAYGTLSPTSLQDFVAPGPMAELVPRAPESPRVPSPPPSP
RLRRRTPVQLLSCPPHLLKSKSEASLLQLLAGAGTHGTPSAPSRSLSELCLAVPAPAQ
EADPGPALPNQDHPAA"
BASE COUNT 694 a 1127 c 1074 g 591 t
ORIGIN
1 gagtcgactg agcccgtccc gcggctcccg tccccctctc cccgcgcgcc ccatgaggct
61 ttggcagtct cggcccgagc cttagagcct tagacaccgg ggaggagacc ctggtcctgt
121 tcctaggtat gtcaccacgc cgactgccag cagctgcacc gccgggggcc cctcaacctc
181 tgcgaggcct gtgacagcaa gttccacagc accatgcatt atgatgggca tgtccgcttc
241 gaccttcccc cacaaggctc tgtgctggcc cggaacgtgt ccacccggtc atgcccgccg
301 cgcaccagcc ccgcagtgga cttggaggag gaggaggagg agagctctgt ggatggcaaa
361 ggggaccgga agagcacagg cctgaaactc tccaagaaga aagcaaggag gagacacacg
421 gatgacccaa gcaaggaatg cttcactctg aaatttgacc tgaatgtgga cattgagaca
481 gagatcgtcc cagccatgaa gaagaagtca ctgggggagg tgctgctgcc tgtatttgaa
541 aggaagggca ttgcgctggg caaagtggac atctacctgg accagtccaa cacacccctg
601 tccctcacct tcgaggccta caggttcggg ggacactacc ttcgtgtcaa agccccagcc
661 aagcctggag atgagggcaa ggtggagcag ggcatgaagg actccaagtc cctgagtttg
721 ccgattctgc ggccagctgg gaccgggccc cccgccctgg agcgtgtgga cgcccagagc
781 cgccgggaga gcctggacat cttggcccct ggccgccgcc gcaagaacat gtcggagttc
841 ctgggggagg cgagcatccc cgggcaggag ccccccacgc cctccagctg ctctctgccc
901 agcggcagca gtggcagcac caacactggc gacagctgga agaaccgggc ggccagtcgc
961 ttcagcggct ttttcagctc cggccccagc accagcgcct ttggccggga ggtagacaag
1021 atggagcagc tggagggcaa gctgcacacc tacagcctct tcgggctgcc caggctgccc
1081 cgggggctgc gcttcgacca tgactcctgg gaggaggagt acgatgaaga cgaggatgag
1141 gacaatgcct gcctgaggct ggaggacagc tggcgggagc tcattgatgg gcatgagaag
1201 ctgacccggc ggcagtgcca ccagcaggag gcggtgtggg agctgctgca cacggaggcc
1261 tcctacatca ggaaactgcg ggtgatcatc aacctgttcc tgtgctgcct cctgaacctg
1321 caagagtcag ggctgctgtg tgaggtggag gcggagcgcc tgttcagcaa catcccggag
1381 atcgcgcagc tgcaccgcag gctgtgggct agcgtgatgg cgccggtgct ggagaaggcg
1441 cggcgcacgc gagcgctgct acagcccggg gacttcctca aaggcttcaa gatgttcggc
1501 tcgctcttca agccctacat ccgctactgc atggaggagg agggctgcat ggagtacatg
1561 cgcggcctgc tgcgcgacaa cgacctcttc cgggcctaca tcacgtgggc ggagaagcac
1621 ccacagtgcc agaggctgaa gctgagcgac atgctggcca aaccccacca gcggctcacc
1681 aagtacccgc tgctgctcaa gtcggtgctg aggaagaccg aggagccgcg cgccaaggag
1741 gccgtcgtcg ccatgatcgg ctccgtggag cgcttcatcc accacgtgaa cgcgtgcatg
1801 cggcagcggc aggagcggca gcggctggcg gccgtggtga gccgcatcga cgcctacgag
1861 gtggtggaaa gcagcagcga cgaagtggac aagctcctga aggaatttct gcacctggac
1921 ttgacagcgc ccatccctgg cgcctccccg gaggagacgc ggcagctgct gctggagggg
1981 agcctgagga tgaaggaggg gaaggacagc aagatggatg tgtactgctt cctcttcacg
2041 gatctgctgt tggtgaccaa agcagtgaag aaggcagaga ggaccagggt catcaggcca
2101 cccctgctcg tggacaagat tgtgtgccgg gagctacggg accctgggtc cttcctcctt
2161 atctacctga atgagtttca cagtgctgta ggggcctaca cgttccaggc cagtggccag
2221 gccttgtgcc gtggctgggt ggacaccatt tacaatgccc agaaccagct gcaacagctg
2281 cgtgcacagg agcccccagg cagtcagcag cccctgcaga gcctggaaga ggaggaggat
2341 gagcaggagg aggaagagga ggaggaggag gaggaggagg aaggcgagga cagtggcact
2401 tcagctgcca gctcccctac catcatgcgg aaaagcagcg gcagccccga ctctcagcac
2461 tgtgcctcag atggctccac ggagaccctg gccatggttg tggtagagcc tggggacacg
2521 ctgtcctccc ccgagttcga cagcggtcct ttcagctccc agtctgatga gacctctctc
2581 agcaccactg cctcatctgc cacgcccacc agtgagctgc tgcccctggg tccggtggac
2641 ggccgctcct gctccatgga ctctgcctac ggcaccctct ccccaacctc cttacaagac
2701 tttgtggccc caggcccaat ggcagagcta gtgcctcggg ccccagagtc cccacgagtt
2761 ccttcccctc caccctcgcc ccgtctccgc cgccgcaccc ctgtccagct gttgagctgc
2821 ccgccccacc tgctcaagtc taagtccgag gccagcctcc tccagctgct ggcaggggct
2881 ggcacccatg ggacaccctc tgcccccagc cgcagcctgt cagagctctg cctggctgtt
2941 ccagccccag cacaggaagc tgaccctggc ccagctctac cgaatcagga ccaccctgct
3001 gcttaactcc acgctcactg cctcggaggt ctgagcagag ggaggccccc aagagtgcca
3061 ttgaccaaga gacagcagac agcctgcctc ctggggcgtg ccggcacctg cttcagctac
3121 tgcctcctgt atgcatgagc cggatgctgg gcaggatccc tgcctacgcc cgggcccgat
3181 ttgcgctttg ccggactgga tggagtggag gaggcccagg ccacagtacc accccacctg
3241 cccaggcagc ccctcgtcac ctactccccg aagttaccag ctcagctcga gtcttcaggg
3301 ctgggctcct aggctgccca tcctacttct accctcactg gcctccagtg ggattcactc
3361 ctgccctgcc cccaccttcc cagtcccaca ggccacccct ggcttgggct gggttctgtg
3421 aagttacgta tttattgagc ttttggttct tttataaaga cttgtctaga caaaaaaaaa
3481 aaaaaa
//