LOCUS BC014897 2140 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens methylcrotonoyl-Coenzyme A carboxylase 2 (beta), mRNA
(cDNA clone MGC:10207 IMAGE:3910739), complete cds.
ACCESSION BC014897
VERSION BC014897.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2140)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2140)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 15 Row: h Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 14251210.
FEATURES Location/Qualifiers
source 1..2140
/db_xref="H-InvDB:HIT000036889_03"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10207 IMAGE:3910739"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_71"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2140
/gene="MCCC2"
/gene_synonym="MCCB"
/db_xref="GeneID:64087"
/db_xref="MIM:210210"
CDS 139..1128
/gene="MCCC2"
/gene_synonym="MCCB"
/codon_start=1
/product="MCCC2 protein"
/protein_id="AAH14897.1"
/db_xref="GeneID:64087"
/db_xref="MIM:210210"
/translation="MWAVLRLALRPCARASPAGPRAYHGDSVASLGTQPDLGSALYQE
NYKQMKALVNQLHERVEHIKLGGGEKARALHISRGKLLPRERIDNLIDPGSPFLELSQ
FAGYQLYDNEEVPGGGIITGIGRVSGVECMIIANDATVKGGAYYPVTVKKQLRAQEIA
MQNRLPCIYLVDSGGAYLPRQADVFPDRDHFGRTFYNQAIMSSKNIAQVKAATGEEVS
AEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKKLDVTIEPSEEPLFPA
DELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGIKPLEKHKT"
misc_feature 283..1101
/gene="MCCC2"
/gene_synonym="MCCB"
/note="COG4799; Region: COG4799, Acetyl-CoA carboxylase,
carboxyltransferase component (subunits alpha and beta)
[Lipid metabolism]"
/db_xref="CDD:COG4799"
BASE COUNT 611 a 447 c 526 g 556 t
ORIGIN
1 acaggcctga gaatcagaga agccttctct ggggctgcaa ggacctgagc tcagcttccg
61 ccccagccag ggaagcggca ggggaaagca ccggctccag gccagcgtgg gccgctctct
121 cgctcggtgc ccgccgccat gtgggccgtc ctgaggttag ccctgcggcc gtgtgcccgc
181 gcctctcccg ccgggccgcg cgcctatcac ggggactcgg tggcctcgct gggcacccag
241 ccggacttgg gctctgccct ctaccaggag aactacaagc agatgaaagc actagtaaat
301 cagctccatg aacgagtgga gcatataaaa ctaggaggtg gtgagaaagc ccgagcactt
361 cacatatcaa gaggaaaact attgcccaga gaaagaattg acaatctcat agacccaggg
421 tctccatttc tggaattatc ccagtttgca ggttaccagt tatatgacaa tgaggaggtg
481 ccaggaggtg gcattattac aggcattgga agagtatcag gagtagaatg catgattatt
541 gccaatgatg ccaccgtcaa aggaggtgcc tactacccag tgactgtgaa aaaacaatta
601 cgggcccaag aaattgccat gcaaaacagg ctcccctgca tctacttagt tgattcggga
661 ggagcatact tacctcgaca agcagatgtg tttccagatc gagaccactt tggccgtaca
721 ttctataatc aggcaattat gtcttctaaa aatattgcac aggttaaagc ggcaactggg
781 gaagaagtat ctgctgagga tcttggaggt gctgatcttc attgcagaaa gtctggagta
841 agtgaccact gggctttgga tgatcatcat gcccttcact taactaggaa ggttgtgagg
901 aatctaaatt atcagaagaa attggatgtc accattgaac cttctgaaga gcctttattt
961 cctgctgatg aattgtatgg aatagttggt gctaacctta agaggagctt tgatgtccga
1021 gaggtcattg ctagaatcgt ggatggaagc agattcactg agttcaaagc cttttatgga
1081 gacacattag ttacaggtat aaagcccttg gaaaagcaca agacataaat cttctttgaa
1141 ctttcttttg aggatttgct cgaatatttg ggtacccagt aggtatcgtt ggaaacaacg
1201 gagttctctt ttctgaatct gcaaaaaagg gtactcactt tgtccagtta tgctgccaaa
1261 gaaatattcc tctgctgttc cttcaaaaca ttactggatt tatggttggt agagagtatg
1321 aagctgaagg aattgccaag gatggtgcca agatggtggc cgctgtggcc tgtgcccaag
1381 tgcctaagat aaccctcatc attgggggct cctatggagc cggaaactat gggatgtgtg
1441 gcagagcgta tagcccaaga tttctctaca tttggccaaa tgctcgtatc tcagtgatgg
1501 gaggagagca ggcagccaat gtgttggcca cgataacaaa ggaccaaaga gcccgggaag
1561 gaaagcagtt ctccagtgct gatgaagcgg ctttaaaaga gcccatcatt aagaagtttg
1621 aagaggaagg aaacccttac tattccagcg caagggtatg ggatgatggg atcattgatc
1681 cagcagacac cagactggtc ttgggtctca gttttagtgc agccctcaac gcaccaatag
1741 agaagactga cttcggtatc ttcaggatgt aactggaata aaggatgttt tctgttggac
1801 atgtactgaa aattaacaca tgtagtagcc ttaaaatttt agacttctcg aacatgaggc
1861 tgttacagta atttttttaa cactgtgcat tgtacttttc taccttaaaa aaatcagtga
1921 ggatatttat ttaatgaaca tcaattcctt ttaaattttc ttagagaaat ttctctgtgg
1981 ctcagtttta ccacccataa agcggagaca gtaatttatg gttatccttt ctgacccaca
2041 aagtatgaaa agttctgtaa tctgtaaact cagttctgta atctgtatta ttgagatgat
2101 taatataaag ttgtattttc actgaaaaaa aaaaaaaaaa
//