LOCUS BC014840 2285 bp mRNA linear HUM 08-DEC-2006
DEFINITION Homo sapiens SMAD family member 2, mRNA (cDNA clone MGC:22139
IMAGE:4449540), complete cds.
ACCESSION BC014840
VERSION BC014840.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2285)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2285)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (01-OCT-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 28 Row: a Column: 9.
FEATURES Location/Qualifiers
source 1..2285
/db_xref="H-InvDB:HIT000036865"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22139 IMAGE:4449540"
/tissue_type="Kidney, hypernephroma"
/clone_lib="NIH_MGC_89"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2285
/gene="SMAD2"
/gene_synonym="hMAD-2"
/gene_synonym="hSMAD2"
/gene_synonym="JV18"
/gene_synonym="JV18-1"
/gene_synonym="MADR2"
/gene_synonym="MGC22139"
/gene_synonym="MGC34440"
/db_xref="GeneID:4087"
/db_xref="HGNC:HGNC:6768"
/db_xref="MIM:601366"
CDS 249..1652
/gene="SMAD2"
/gene_synonym="hMAD-2"
/gene_synonym="hSMAD2"
/gene_synonym="JV18"
/gene_synonym="JV18-1"
/gene_synonym="MADR2"
/gene_synonym="MGC22139"
/gene_synonym="MGC34440"
/codon_start=1
/product="SMAD family member 2"
/protein_id="AAH14840.1"
/db_xref="GeneID:4087"
/db_xref="HGNC:HGNC:6768"
/db_xref="MIM:601366"
/translation="MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKA
VKSLVKKLKKTGRLDELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLY
SFSEQTRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEV
CVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIP
ETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCS
IAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGR
GVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAA
LLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD
KVLTQMGSPSVRCSSMS"
BASE COUNT 697 a 479 c 508 g 601 t
ORIGIN
1 gcgcccgggc cgccggccgg gcccgggcct gggggcgggg cgggaagacg gcggccggga
61 gtgttttcag ttccgcctcc aatcgcccat tcccctcttc ccctcccagc cccctccatc
121 ccatcggaag aggaaggaac aaaaggtccc ggaccccccg gatctgacgg ggcgggacct
181 ggcgccacct tgcaggttcg atacaagagg ctgttttcct agcgtggctt gctgcctttg
241 gtaagaacat gtcgtccatc ttgccattca cgccgccagt tgtgaagaga ctgctgggat
301 ggaagaagtc agctggtggg tctggaggag caggcggagg agagcagaat gggcaggaag
361 aaaagtggtg tgagaaagca gtgaaaagtc tggtgaagaa gctaaagaaa acaggacgat
421 tagatgagct tgagaaagcc atcaccactc aaaactgtaa tactaaatgt gttaccatac
481 caagcacttg ctctgaaatt tggggactga gtacaccaaa tacgatagat cagtgggata
541 caacaggcct ttacagcttc tctgaacaaa ccaggtctct tgatggtcgt ctccaggtat
601 cccatcgaaa aggattgcca catgttatat attgccgatt atggcgctgg cctgatcttc
661 acagtcatca tgaactcaag gcaattgaaa actgcgaata tgcttttaat cttaaaaagg
721 atgaagtatg tgtaaaccct taccactatc agagagttga gacaccagtt ttgcctccag
781 tattagtgcc ccgacacacc gagatcctaa cagaacttcc gcctctggat gactatactc
841 actccattcc agaaaacact aacttcccag caggaattga gccacagagt aattatattc
901 cagaaacgcc acctcctgga tatatcagtg aagatggaga aacaagtgac caacagttga
961 atcaaagtat ggacacaggc tctccagcag aactatctcc tactactctt tcccctgtta
1021 atcatagctt ggatttacag ccagttactt actcagaacc tgcattttgg tgttcgatag
1081 catattatga attaaatcag agggttggag aaaccttcca tgcatcacag ccctcactca
1141 ctgtagatgg ctttacagac ccatcaaatt cagagaggtt ctgcttaggt ttactctcca
1201 atgttaaccg aaatgccacg gtagaaatga caagaaggca tataggaaga ggagtgcgct
1261 tatactacat aggtggggaa gtttttgctg agtgcctaag tgatagtgca atctttgtgc
1321 agagccccaa ttgtaatcag agatatggct ggcaccctgc aacagtgtgt aaaattccac
1381 caggctgtaa tctgaagatc ttcaacaacc aggaatttgc tgctcttctg gctcagtctg
1441 ttaatcaggg ttttgaagcc gtctatcagc taactagaat gtgcaccata agaatgagtt
1501 ttgtgaaagg gtggggagca gaataccgaa ggcagacggt aacaagtact ccttgctgga
1561 ttgaacttca tctgaatgga cctctacagt ggttggacaa agtattaact cagatgggat
1621 ccccttcagt gcgttgctca agcatgtcat aaagcttcac caatcaagtc ccatgaaaag
1681 acttaatgta acaactcttc tgtcatagca ttgtgtgtgg tccctatgga ctgtttacta
1741 tccaaaagtt caagagagaa aacagcactt gaggtctcat caattaaagc accttgtgga
1801 atctgtttcc tatatttgaa tattagatgg gaaaattagt gtctagaaat actctcccat
1861 taaagaggaa gagaagattt taaagactta atgatgtctt attgggcata aaactgagtg
1921 tcccaaaggt ttattaataa cagtagtagt tatgtgtaca ggtaatgtat catgatccag
1981 tatcacagta ttgtgctgtt tatatacatt tttagtttgc atagatgagg tgtgtgtgtg
2041 cgctgcttct tgatctaggc aaacctttat aaagttgcag tacctaatct gttattccca
2101 cttctctgtt atttttgtgt gtctttttta atatataata tatatcaaga ttttcaaatt
2161 atttagaagc agattttcct gtagaaaaac taatttttct gccttttacc aaaaataaac
2221 tcttggggga agaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2281 aaaaa
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