LOCUS BC014485 2556 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens heat shock protein 90kDa alpha (cytosolic), class B
member 1, mRNA (cDNA clone MGC:23206 IMAGE:4870198), complete cds.
ACCESSION BC014485
VERSION BC014485.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2556)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2556)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 34 Row: l Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..2556
/db_xref="H-InvDB:HIT000036733"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:23206 IMAGE:4870198"
/tissue_type="Skin, melanotic melanoma, high MDR."
/clone_lib="NIH_MGC_49"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2556
/gene="HSP90AB1"
/gene_synonym="D6S182"
/gene_synonym="HSP90-BETA"
/gene_synonym="HSP90B"
/db_xref="GeneID:3326"
/db_xref="HGNC:HGNC:5258"
/db_xref="MIM:140572"
CDS 80..2254
/gene="HSP90AB1"
/gene_synonym="D6S182"
/gene_synonym="HSP90-BETA"
/gene_synonym="HSP90B"
/codon_start=1
/product="heat shock protein 90kDa alpha (cytosolic),
class B member 1"
/protein_id="AAH14485.1"
/db_xref="GeneID:3326"
/db_xref="HGNC:HGNC:5258"
/db_xref="MIM:140572"
/translation="MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELI
SNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNL
GTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESS
AGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLE
KEREKEISDDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKY
IDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF
IPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISR
EMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRR
LSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGF
EVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKL
MKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKK
HLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYR
MIKLGLGIDEDEVAAEEPNAAVPDEIPPLEGDEDASRMEEVD"
BASE COUNT 735 a 545 c 652 g 624 t
ORIGIN
1 gcgcagtgtt gggactgtct gggtatcgga aagcaagcct acgttgctca ctattacgta
61 taatcctttt cttttcaaga tgcctgagga agtgcaccat ggagaggagg aggtggagac
121 ttttgccttt caggcagaaa ttgcccaact catgtccctc atcatcaata ccttctattc
181 caacaaggag attttccttc gggagttgat ctctaatgct tctgatgcct tggacaagat
241 tcgctatgag agcctgacag acccttcgaa gttggacagt ggtaaagagc tgaaaattga
301 catcatcccc aaccctcagg aacgtaccct gactttggta gacacaggca ttggcatgac
361 caaagctgat ctcataaata atttgggaac cattgccaag tctggtacta aagcattcat
421 ggaggctctt caggctggtg cagacatctc catgattggg cagtttggtg ttggctttta
481 ttctgcctac ttggtggcag agaaagtggt tgtgatcaca aagcacaacg atgatgaaca
541 gtatgcttgg gagtcttctg ctggaggttc cttcactgtg cgtgctgacc atggtgagcc
601 cattggcagg ggtaccaaag tgatcctcca tcttaaagaa gatcagacag agtacctaga
661 agagaggcgg gtcaaagaag tagtgaagaa gcattctcag ttcataggct atcccatcac
721 cctttatttg gagaaggaac gagagaagga aattagtgat gatgaggcag aggaagagaa
781 aggtgagaaa gaagaggaag ataaagatga tgaagaaaag cccaagatcg aagatgtggg
841 ttcagatgag gaggatgaca gcggtaagga taagaagaag aaaactaaga agatcaaaga
901 gaaatacatt gatcaggaag aactaaacaa gaccaagcct atttggacca gaaaccctga
961 tgacatcacc caagaggagt atggagaatt ctacaagagc ctcactaatg actgggaaga
1021 ccacttggca gtcaagcact tttctgtaga aggtcagttg gaattcaggg cattgctatt
1081 tattcctcgt cgggctccct ttgacctttt tgagaacaag aagaaaaaga acaacatcaa
1141 actctatgtc cgccgtgtgt tcatcatgga cagctgtgat gagttgatac cagagtatct
1201 caattttatc cgtggtgtgg ttgactctga ggatctgccc ctgaacatct cccgagaaat
1261 gctccagcag agcaaaatct tgaaagtcat tcgcaaaaac attgttaaga agtgccttga
1321 gctcttctct gagctggcag aagacaagga gaattacaag aaattctatg aggcattctc
1381 taaaaatctc aagcttggaa tccacgaaga ctccactaac cgccgccgcc tgtctgagct
1441 gctgcgctat catacctccc agtctggaga tgagatgaca tctctgtcag agtatgtttc
1501 tcgcatgaag gagacacaga agtccatcta ttacatcact ggtgagagca aagagcaggt
1561 ggccaactca gcttttgtgg agcgagtgcg gaaacggggc ttcgaggtgg tatatatgac
1621 cgagcccatt gacgagtact gtgtgcagca gctcaaggaa tttgatggga agagcctggt
1681 ctcagttacc aaggagggtc tggagctgcc tgaggatgag gaggagaaga agaagatgga
1741 agagagcaag gcaaagtttg agaacctctg caagctcatg aaagaaatct tagataagaa
1801 ggttgagaag gtgacaatct ccaatagact tgtgtcttca ccttgctgca ttgtgaccag
1861 cacctacggc tggacagcca atatggagcg gatcatgaaa gcccaggcac ttcgggacaa
1921 ctccaccatg ggctatatga tggccaaaaa gcacctggag atcaaccctg accaccccat
1981 tgtggagacg ctgcggcaga aggctgaggc cgacaagaat gataaggcag ttaaggacct
2041 ggtggtgctg ctgtttgaaa ccgccctgct atcttctggc ttttcccttg aggatcccca
2101 gacccactcc aaccgcatct atcgcatgat caagctaggt ctaggtattg atgaagatga
2161 agtggcagca gaggaaccca atgctgcagt tcctgatgag atcccccctc tcgagggcga
2221 tgaggatgcg tctcgcatgg aagaagtcga ttaggttagg agttcatagt tggaaaactt
2281 gtgcccttgt atagtgtccc catgggctcc cactgcagcc tcgagtgccc ctgtcccacc
2341 tggctccccc tgctggtgtc tagtgttttt ttccctctcc tgtccttgtg ttgaaggcag
2401 taaactaagg gtgtcaagcc ccattccctc tctactcttg acagcaggat tggatgttgt
2461 gtattgtggt ttattttatt ttcttcattt tgttctgaaa ttaaagtatg caaaataaag
2521 aatatgccgt ttttatacaa aaaaaaaaaa aaaaaa
//