LOCUS BC014327 1462 bp mRNA linear HUM 02-DEC-2006
DEFINITION Homo sapiens hydroxysteroid (17-beta) dehydrogenase 11, mRNA (cDNA
clone MGC:22858 IMAGE:3961721), complete cds.
ACCESSION BC014327
VERSION BC014327.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1462)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1462)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 31 Row: j Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..1462
/db_xref="H-InvDB:HIT000036643"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:22858 IMAGE:3961721"
/tissue_type="Bladder, carcinoma"
/clone_lib="NIH_MGC_53"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1462
/gene="HSD17B11"
/gene_synonym="DHRS8"
/gene_synonym="PAN1B"
/gene_synonym="RETSDR2"
/db_xref="GeneID:51170"
/db_xref="HGNC:HGNC:22960"
CDS 100..1002
/gene="HSD17B11"
/gene_synonym="DHRS8"
/gene_synonym="PAN1B"
/gene_synonym="RETSDR2"
/codon_start=1
/product="hydroxysteroid (17-beta) dehydrogenase 11"
/protein_id="AAH14327.1"
/db_xref="GeneID:51170"
/db_xref="HGNC:HGNC:22960"
/translation="MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGA
GHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYS
SAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMT
KNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCP
NFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPER
FLAVLKRKISVKFDAVIGYKMKAQ"
BASE COUNT 466 a 261 c 285 g 450 t
ORIGIN
1 ggggactctt tctggtgtta gatcgagcta ccctctaaaa gcagtttaga gtggtaaaaa
61 aaaaaaaaaa cacaccaaac gctcgcagcc acaaaaggga tgaaatttct tctggacatc
121 ctcctgcttc tcccgttact gatcgtctgc tccctagagt ccttcgtgaa gctttttatt
181 cctaagagga gaaaatcagt caccggcgaa atcgtgctga ttacaggagc tgggcatgga
241 attgggagac tgactgccta tgaatttgct aaacttaaaa gcaagctggt tctctgggat
301 ataaataagc atggactgga ggaaacagct gccaaatgca agggactggg tgccaaggtt
361 catacctttg tggtagactg cagcaaccga gaagatattt acagctctgc aaagaaggtg
421 aaggcagaaa ttggagatgt tagtatttta gtaaataatg ctggtgtagt ctatacatca
481 gatttgtttg ctacacaaga tcctcagatt gaaaagactt ttgaagttaa tgtacttgca
541 catttctgga ctacaaaggc atttcttcct gcaatgacga agaataacca tggccatatt
601 gtcactgtgg cttcggcagc tggacatgtc tcggtcccct tcttactggc ttactgttca
661 agcaagtttg ctgctgttgg atttcataaa actttgacag atgaactggc tgccttacaa
721 ataactggag tcaaaacaac atgtctgtgt cctaatttcg taaacactgg cttcatcaaa
781 aatccaagta caagtttggg acccactctg gaacctgagg aagtggtaaa caggctgatg
841 catgggattc tgactgagca gaagatgatt tttattccat cttctatagc ttttttaaca
901 acattggaaa ggatccttcc tgagcgtttc ctggcagttt taaaacgaaa aatcagtgtt
961 aagtttgatg cagttattgg atataaaatg aaagcgcaat aagcacctag ttttctgaaa
1021 actgatttac caggtttagg ttgatgtcat ctaatagtgc cagaatttta atgtttgaac
1081 ttctgttttt tctaattatc cccatttctt caatatcatt tttgaggctt tggcagtctt
1141 catttactac cacttgttct ttagccaaaa gctgattaca tatgatataa acagagaaat
1201 acctttagag gtgactttaa ggaaaatgaa gaaaaagaac caaaatgact ttattaaaat
1261 aatttccaag attatttgtg gctcacctga aggctttgca aaatttgtac cataaccgtt
1321 tatttaacat atatttttat ttttgattgc acttaaattt tgtataattt gtgtttcttt
1381 ttctgttcta cataaaatca gaaacttcaa gctctctaaa taaaatgaag gactgtaaaa
1441 aaaaaaaaaa aaaaaaaaaa aa
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