LOCUS BC014277 2533 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens TIMP metallopeptidase inhibitor 3, mRNA (cDNA clone
MGC:11079 IMAGE:3689386), complete cds.
ACCESSION BC014277
VERSION BC014277.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2533)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2533)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC014277.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 14 Row: e Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 21536431.
FEATURES Location/Qualifiers
source 1..2533
/db_xref="H-InvDB:HIT000036620"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:11079 IMAGE:3689386"
/tissue_type="Pancreas, adenocarcinoma"
/clone_lib="NIH_MGC_39"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2533
/gene="TIMP3"
/gene_synonym="HSMRK222"
/gene_synonym="K222"
/gene_synonym="K222TA2"
/db_xref="GeneID:7078"
/db_xref="HGNC:HGNC:11822"
/db_xref="MIM:188826"
CDS 244..879
/gene="TIMP3"
/gene_synonym="HSMRK222"
/gene_synonym="K222"
/gene_synonym="K222TA2"
/codon_start=1
/product="TIMP metallopeptidase inhibitor 3"
/protein_id="AAH14277.1"
/db_xref="GeneID:7078"
/db_xref="HGNC:HGNC:11822"
/db_xref="MIM:188826"
/translation="MTPWLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRA
KVVGKKLVKEGPFGTLVYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVNKYQY
LLTGRVYDGKMYTGLCNFVERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSK
NECLWTDMLSNFGYPGYQSKHYACIRQKGGYCSWYRGWAPPDKSIINATDP"
BASE COUNT 618 a 673 c 605 g 637 t
ORIGIN
1 gctcctccag ctcctgctcc ttcgccggga ggccgcccgc cgagtcctgc gccagcgccg
61 aggcagcctc gctgcgcccc atcccgtccc gccgggcact cggagggcag cgcgccggag
121 gccaaggttg ccccgcacgg cccggcgggc gagcgagctc gggctgcagc agccccgccg
181 gcggcgcgca cggcaacttt ggagaggcga gcagcagccc cggcagcggc ggcagcagcg
241 gcaatgaccc cttggctcgg gctcatcgtg ctcctgggca gctggagcct gggggactgg
301 ggcgccgagg cgtgcacatg ctcgcccagc cacccccagg acgccttctg caactccgac
361 atcgtgatcc gggccaaggt ggtggggaag aagctggtaa aggaggggcc cttcggcacg
421 ctggtctaca ccatcaagca gatgaagatg taccgaggct tcaccaagat gccccatgtg
481 cagtacatcc atacggaagc ttccgagagt ctctgtggcc ttaagctgga ggtcaacaag
541 taccagtacc tgctgacagg tcgcgtctat gatggcaaga tgtacacggg gctgtgcaac
601 ttcgtggaga ggtgggacca gctcaccctc tcccagcgca aggggctgaa ctatcggtat
661 cacctgggtt gtaactgcaa gatcaagtcc tgctactacc tgccttgctt tgtgacttcc
721 aagaacgagt gtctctggac cgacatgctc tccaatttcg gttaccctgg ctaccagtcc
781 aaacactacg cctgcatccg gcagaagggc ggctactgca gctggtaccg aggatgggcc
841 cccccggata aaagcatcat caatgccaca gacccctgag cgccagaccc tgccccacct
901 cacttccctc ccttcccgct gagcttccct tggacactaa ctcttcccag atgatgacaa
961 tgaaattagt gcctgttttc ttgcaaattt agcacttgga acatttaaag aaaggtctat
1021 gctgtcatat ggggtttatt gggaactatc ctcctggccc caccctgccc cttctttttg
1081 gttttgacat cattcatttc cacctgggaa tttctggtgc catgccagaa agaatgagga
1141 acctgtattc ctcttcttcg tgataatata atctctattt ttttaggaaa acaaaaatga
1201 aaaactactc catttgagga ttgtaattcc cacccctctt gcttcttccc cacctcacca
1261 tctcccagac cctcttccct ttgcccttct cctccaatac ataaaggaca cagacaagga
1321 acttgctgaa aggccaacca tttcaggatc agtcaaaggc agcaagcaga tagactcaag
1381 gtgtgtgaaa gatgttatac accaggagct gccactgcat gtcccaacca gactgtgtct
1441 gtctgtgtct gcatgtaaga gtgagggagg gaaggaagga actacaagag agtcggagat
1501 gatgcagcac acacacaatt ccccagccca gtgatgcttg tgttgaccag atgttcctga
1561 gtctggagca agcacccagg ccagaataac agagctttct tagttggtga agacttaaac
1621 atctgcctga ggtcaggagg caatttgcct gccttgtaca aaagctcagg tgaaagactg
1681 agatgaatgt ctttcctctc cctgcctccc accagacttc ctcctggaaa acgctttggt
1741 agatttggcc aggagctttc ttttatgtaa attggataaa tacacacacc atacactatc
1801 cacagatata gccaagtaga tttgggtaga ggatactatt tccagaatag tgtttagctc
1861 acctaggggg atatgtttgt atacacattt gcatataccc acatggggac ataagctaat
1921 ttttttacag gacacagaat tctgttcaat gctgttaaat atgccaatag tttaatctct
1981 tctattttgt tgtcgttgct tgtttgaaga aaatcatgac attccaagtt gacatttttt
2041 tttcatttta attaaaattt gaaattctga acaccgtcag caccctctct tccctatcat
2101 gggtcatctg acccctgtcc gtctccttgt ccctgcttca tgtttggggg cctttcttta
2161 actgccttcc tggcttagct cagatggcag atgagagtgt agtcaagggc ctgggcacag
2221 gagggagagc tgcagagtgt cctgcctgcc ttggctggag ggacacctct cctgggtgtg
2281 gagacagctt ggttcccttt ccctagctcc ctggtgggtg aatgccacct cctgagatcc
2341 tcacctcttg gaattaaaat tgttggtcac tggggaaagc ctgagtttgc aaccagttgt
2401 agggtttctg ttgtgttttt tttttttttt ttgaaataaa actataatat aaattctcct
2461 attaaataaa attattttaa gttttagtgt caaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2521 aaaaaaaaaa aaa
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