LOCUS BC014239 2352 bp mRNA linear HUM 16-SEP-2003
DEFINITION Homo sapiens protein tyrosine phosphatase, receptor type, C, mRNA
(cDNA clone IMAGE:4565766), partial cds.
ACCESSION BC014239
VERSION BC014239.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2352)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2352)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (10-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC014239.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis Staudt
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 30 Row: j Column: 12
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 18641346.
FEATURES Location/Qualifiers
source 1..2352
/db_xref="H-InvDB:HIT000088335"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4565766"
/tissue_type="Primary B-Cells from Tonsils"
/clone_lib="NIH_MGC_48"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..>2352
/gene="PTPRC"
/gene_synonym="B220"
/gene_synonym="CD45"
/gene_synonym="GP180"
/gene_synonym="LCA"
/gene_synonym="LY5"
/gene_synonym="T200"
/db_xref="GeneID:5788"
/db_xref="MIM:151460"
CDS 84..>2352
/gene="PTPRC"
/gene_synonym="B220"
/gene_synonym="CD45"
/gene_synonym="GP180"
/gene_synonym="LCA"
/gene_synonym="LY5"
/gene_synonym="T200"
/codon_start=1
/product="PTPRC protein"
/protein_id="AAH14239.1"
/db_xref="GeneID:5788"
/db_xref="MIM:151460"
/translation="MYLWLKLLAFGFAFLDTEVFVTGQSPTPSPTGLTTAKMPSVPLS
SDPLPTHTTAFSPASTFERENDFSETTTSLSPDNTSTQVSPDSLDNASAFNTTGVSSV
QTPHLPTHADSQTPSAGTDTQTFSGSAANAKLNPTPGSNAISDAYLNASETTTLSPSG
SAVISTTTIATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNN
EVHNLTECKNASVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWK
NIETFTCDTQNITYRFQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKI
IKTDFGSPGEPQIIFCRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLI
KYDLQNLKPYTKYVLSLHAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNS
MHVKCRPPRDRNGPHERYHLEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHN
GDYPGEPFILHHSTSYNSKALIAFLAFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQ
ELVERDDEKQLMNVEPIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARK
PFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDET
VDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCP
DYIIQKLNIVNKKKKK"
misc_feature 1107..1319
/gene="PTPRC"
/gene_synonym="B220"
/gene_synonym="CD45"
/gene_synonym="GP180"
/gene_synonym="LCA"
/gene_synonym="LY5"
/gene_synonym="T200"
/note="FN3; Region: Fibronectin type 3 domain"
/db_xref="CDD:smart00060"
misc_feature 1395..1628
/gene="PTPRC"
/gene_synonym="B220"
/gene_synonym="CD45"
/gene_synonym="GP180"
/gene_synonym="LCA"
/gene_synonym="LY5"
/gene_synonym="T200"
/note="fn3; Region: Fibronectin type III domain"
/db_xref="CDD:pfam00041"
misc_feature 1887..2336
/gene="PTPRC"
/gene_synonym="B220"
/gene_synonym="CD45"
/gene_synonym="GP180"
/gene_synonym="LCA"
/gene_synonym="LY5"
/gene_synonym="T200"
/note="PTPc; Region: Protein tyrosine phosphatase,
catalytic domain"
/db_xref="CDD:smart00194"
BASE COUNT 785 a 486 c 444 g 637 t
ORIGIN
1 aattgttcct cgtctgataa gacaacagtg gagaaaggac gcatgctgtt tcttagggac
61 acggctgact tccagatatg accatgtatt tgtggcttaa actcttggca tttggctttg
121 cctttctgga cacagaagta tttgtgacag ggcaaagccc aacaccttcc cccactggat
181 tgactacagc aaagatgccc agtgttccac tttcaagtga ccccttacct actcacacca
241 ctgcattctc acccgcaagc acctttgaaa gagaaaatga cttctcagag accacaactt
301 ctcttagtcc agacaatact tccacccaag tatccccgga ctctttggat aatgctagtg
361 cttttaatac cacaggtgtt tcatcagtac agacgcctca ccttcccacg cacgcagact
421 cgcagacgcc ctctgctgga actgacacgc agacattcag cggctccgcc gccaatgcaa
481 aactcaaccc taccccaggc agcaatgcta tctcagatgc ctaccttaat gcctctgaaa
541 caaccactct gagcccttct ggaagcgctg tcatttcaac cacaacaata gctactactc
601 catctaagcc aacatgtgat gaaaaatatg caaacatcac tgtggattac ttatataaca
661 aggaaactaa attatttaca gcaaagctaa atgttaatga gaatgtggaa tgtggaaaca
721 atacttgcac aaacaatgag gtgcataacc ttacagaatg taaaaatgcg tctgtttcca
781 tatctcataa ttcatgtact gctcctgata agacattaat attagatgtg ccaccagggg
841 ttgaaaagtt tcagttacat gattgtacac aagttgaaaa agcagatact actatttgtt
901 taaaatggaa aaatattgaa acctttactt gtgatacaca gaatattacc tacagatttc
961 agtgtggtaa tatgatattt gataataaag aaattaaatt agaaaacctt gaacccgaac
1021 atgagtataa gtgtgactca gaaatactct ataataacca caagtttact aacgcaagta
1081 aaattattaa aacagatttt gggagtccag gagagcctca gattattttt tgtagaagtg
1141 aagctgcaca tcaaggagta attacctgga atccccctca aagatcattt cataatttta
1201 ccctctgtta tataaaagag acagaaaaag attgcctcaa tctggataaa aacctgatca
1261 aatatgattt gcaaaattta aaaccttata cgaaatatgt tttatcatta catgcctaca
1321 tcattgcaaa agtgcaacgt aatggaagtg ctgcaatgtg tcatttcaca actaaaagtg
1381 ctcctccaag ccaggtctgg aacatgactg tctccatgac atcagataat agtatgcatg
1441 tcaagtgtag gcctcccagg gaccgtaatg gcccccatga acgttaccat ttggaagttg
1501 aagctggaaa tactctggtt agaaatgagt cgcataagaa ttgcgatttc cgtgtaaaag
1561 atcttcaata ttcaacagac tacactttta aggcctattt tcacaatgga gactatcctg
1621 gagaaccctt tattttacat cattcaacat cttataattc taaggcactg atagcatttc
1681 tggcatttct gattattgtg acatcaatag ccctgcttgt tgttctctac aaaatctatg
1741 atctacataa gaaaagatcc tgcaatttag atgaacagca ggagcttgtt gaaagggatg
1801 atgaaaaaca actgatgaat gtggagccaa tccatgcaga tattttgttg gaaacttata
1861 agaggaagat tgctgatgaa ggaagacttt ttctggctga atttcagagc atcccgcggg
1921 tgttcagcaa gtttcctata aaggaagctc gaaagccctt taaccagaat aaaaaccgtt
1981 atgttgacat tcttccttat gattataacc gtgttgaact ctctgagata aacggagatg
2041 cagggtcaaa ctacataaat gccagctata ttgatggttt caaagaaccc aggaaataca
2101 ttgctgcaca aggtcccagg gatgaaactg ttgatgattt ctggaggatg atttgggaac
2161 agaaagccac agttattgtc atggtcactc gatgtgaaga aggaaacagg aacaagtgtg
2221 cagaatactg gccgtcaatg gaagagggca ctcgggcttt tggagatgtt gttgtaaaga
2281 tcaaccagca caaaagatgt ccagattaca tcattcagaa attgaacatt gtaaataaaa
2341 aaaaaaaaaa aa
//