LOCUS BC014107 1613 bp mRNA linear HUM 08-OCT-2003
DEFINITION Homo sapiens aarF domain containing kinase 2, mRNA (cDNA clone
MGC:20727 IMAGE:4138734), complete cds.
ACCESSION BC014107
VERSION BC014107.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1613)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1613)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (10-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 20, 2003 this sequence version replaced BC014107.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 30 Row: c Column: 5
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 16418352.
FEATURES Location/Qualifiers
source 1..1613
/db_xref="H-InvDB:HIT000036523"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20727 IMAGE:4138734"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1613
/gene="ADCK2"
/gene_synonym="AARF"
/gene_synonym="MGC20727"
/db_xref="GeneID:90956"
CDS 176..1399
/gene="ADCK2"
/gene_synonym="AARF"
/gene_synonym="MGC20727"
/codon_start=1
/product="ADCK2 protein"
/protein_id="AAH14107.1"
/db_xref="GeneID:90956"
/translation="MVAPWRVSVRVCLSHLRCFELRQGLSLLRPSECPRDARLCWLLL
GTLPKVVSLCGDVGEGAPDVLSRRRVRCSGAAGAGPAESLPRAGPLGGVFLHLRLWLR
AGALLVKFFPLLLLYPLTYLAPSVSTLWLHLLLKATETSGPTYIKLGQWASTRRDLFS
EAFCAQFSKLHVRVTPHPWTHTERFLRQAFGDDWGSILSFENREPVGSGCVAQVYKAY
ANTAFLETDSVQRLGRASCLPPFSHTGAVGGLRELFGYLGNGRKPPENLADQSFLERL
LLPKADLVGSNAGVSRAQVPGHQPEATNLISVAVKVLHPGLLAQVHMDLLLMKIGSRV
LGVLPGIKWLSLPEIVEEFEKLMVQQIDLRYEAQNLEHFQVNFRNVKAVKFPTPKSLS
YGSWDVLKLGHQFQM"
misc_feature 575..826
/gene="ADCK2"
/gene_synonym="AARF"
/gene_synonym="MGC20727"
/note="Region: Predicted unusual protein kinase [General
function prediction only]"
/db_xref="CDD:COG0661"
misc_feature 1037..1339
/gene="ADCK2"
/gene_synonym="AARF"
/gene_synonym="MGC20727"
/note="ABC1; Region: ABC1 family. This family includes
ABC1 from yeast and AarF from E. coli. These proteins have
a nuclear or mitochondrial subcellular location in
eukaryotes. The exact molecular functions of these
proteins is not clear, however yeast ABC1 suppresses a
cytochrome b mRNA translation defect and is essential for
the electron transfer in the bc 1 complex and E. coli AarF
is required for ubiquinone production. It has been
suggested that members of the ABC1 family are novel
chaperonins. These proteins are unrelated to the ABC
transporter proteins"
/db_xref="CDD:pfam03109"
BASE COUNT 299 a 477 c 493 g 344 t
ORIGIN
1 gcgggcctcc ggcctgaggc ccggcgaggt gctggaggga gcggggcgcg gatccggccc
61 agatgggcag ctccgtccgc ggggtcaggg ccgggcttcg gcttcaccgc agcctcgcct
121 gagcgggcgc ctctgaagtg gagggcgggc cgcctgggcc gcgggcctcg ggaggatggt
181 ggcgccctgg cgcgtctccg tcagggtttg cctgtcgcac ctgaggtgct tcgagctcag
241 acagggactc agcctcctga ggccctccga gtgccctcgc gatgccaggc tctgctggct
301 tctgctgggc actttgccca aggtcgtctc cctgtgcggg gacgtgggtg agggggcccc
361 tgacgttctg agtcggcgaa gggtccgctg cagcggggcg gctggcgcgg ggcccgcgga
421 gagcctcccc cgagcgggac ctctgggcgg cgtcttcctg catctccgcc tctggcttcg
481 cgccggcgct ctgttggtga aattcttccc cctcctactc ctctaccccc tcacctacct
541 ggctcccagc gtctccaccc tctggctcca cctgcttctg aaagccaccg agacctcagg
601 cccaacctac atcaaactgg gccagtgggc cagcacccgg cgcgatctgt tttcggaggc
661 tttctgtgcc caattttcca agctgcatgt ccgagtgacg ccccacccgt ggactcacac
721 tgagcgcttc cttcggcagg cttttgggga tgactggggg agcatcctct cttttgagaa
781 ccgggaacct gtgggctcag gctgcgtggc ccaggtgtac aaagcatacg ccaacactgc
841 cttcctggag actgacagcg tccagagact tggcagggcc tcctgtctgc cgcccttctc
901 acatactggg gcagtcggtg ggctgagaga gctctttgga taccttggaa atggccggaa
961 acctccagaa aatctcgcag accagtcgtt tctagaaagg ctgctcctcc ctaaagctga
1021 cctggttgga tcaaatgcag gggtgtctcg ggctcaggtc cctggccacc aacctgaggc
1081 caccaacctc atctccgtgg cagtgaaagt gttgcaccct ggcctgctcg ctcaggtgca
1141 tatggacctg ctgctgatga agattggcag ccgagtcctg ggagttttgc caggcatcaa
1201 gtggcttagc ttgcctgaga ttgtggagga atttgagaag ctgatggtcc aacagattga
1261 cctgcgttac gaagctcaga atctagaaca cttccaggtc aacttccgga atgtgaaagc
1321 cgtcaagttc cccactccca agagcctctc ctatggcagc tgggacgttt taaaattggg
1381 acaccaattt caaatgtaac cctccagtgg tggaaggcac accatggctt cctctgcttg
1441 gtttgagggt ctgttcaaaa gctttgggcc aattagggag taaaaggagg gaaggggcct
1501 atccattcca ttgtggaagc tgggccaggt gccagggaca ctctccttca gggaaaatgt
1561 tatgtggagg aggacgaata aatttatttt gttttaaaaa aaaaaaaaaa aaa
//