LOCUS BC014092 2747 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens aconitase 2, mitochondrial, mRNA (cDNA clone MGC:20605
IMAGE:4328775), complete cds.
ACCESSION BC014092
VERSION BC014092.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2747)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2747)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC014092.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 28 Row: n Column: 24
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 46411160.
FEATURES Location/Qualifiers
source 1..2747
/db_xref="H-InvDB:HIT000036514"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20605 IMAGE:4328775"
/tissue_type="Uterus, leiomyosarcoma"
/clone_lib="NIH_MGC_46"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2747
/gene="ACO2"
/gene_synonym="aconitase"
/gene_synonym="ACONM"
/gene_synonym="MGC20605"
/gene_synonym="MGC33908"
/db_xref="GeneID:50"
/db_xref="HGNC:HGNC:118"
/db_xref="MIM:100850"
CDS 23..2365
/gene="ACO2"
/gene_synonym="aconitase"
/gene_synonym="ACONM"
/gene_synonym="MGC20605"
/gene_synonym="MGC33908"
/codon_start=1
/product="aconitase 2, mitochondrial"
/protein_id="AAH14092.1"
/db_xref="GeneID:50"
/db_xref="HGNC:HGNC:118"
/db_xref="MIM:100850"
/translation="MAPYSLLVTRLQKALGVRQYHVASVLCQRAKVAMSHFEPNEYIH
YDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPASQEIERGKSYLRLRPDRVAMQDAT
AQMAMLQFISSGLSKVAVPSTIHCDHLIEAQVGGEKDLRRAKDINQEVYNFLATAGAK
YGVGFWKPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMA
GIPWELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSIS
CTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGREDIANLADEFKDHLVPDPGCHY
DQLIEINLSELKPHINGPFTPDLAHPVAEVGKVAEKEGWPLDIRVGLIGSCTNSSYED
MGRSAAVAKQALAHGLKCKSQFTITPGSEQIRATIERDGYAQILRDLGGIVLANACGP
CIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFN
PETDYLTGTDGKKFRLEAPDADELPKGEFDPGQDTYQHPPKDSSGQHVDVSPTSQRLQ
LLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINI
ENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLG
GRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPVDKLTIQGLKDFTPGKPLKC
IIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ"
BASE COUNT 662 a 778 c 754 g 553 t
ORIGIN
1 ctcatctttg tcagtgcaca aaatggcgcc ctacagccta ctggtgactc ggctgcagaa
61 agctctgggt gtgcggcagt accatgtggc ctcagtcctg tgccaacggg ccaaggtggc
121 gatgagccac tttgagccca acgagtacat ccattatgac ctgctagaga agaacattaa
181 cattgttcgc aaacgactga accggccgct gaccctctcg gagaagattg tgtatggaca
241 cctggatgac cccgccagcc aggaaattga gcgaggcaag tcgtacctgc ggctgcggcc
301 ggaccgtgtg gccatgcagg atgcgacggc ccagatggcc atgctccagt tcatcagcag
361 cgggctgtcc aaggtggctg tgccatccac catccactgt gaccatctga ttgaagccca
421 ggttgggggc gagaaagacc tgcgccgggc caaggacatc aaccaggaag tttataattt
481 cctggcaact gcaggtgcca aatatggcgt gggcttctgg aagcctggat ctggaatcat
541 tcaccagatt attctggaaa actatgcgta ccctggtgtt cttctgattg gcactgactc
601 ccacaccccc aatggtggcg gccttggggg catctgcatt ggagttgggg gtgccgatgc
661 tgtggatgtc atggctggga tcccctggga gctgaagtgc cccaaggtga ttggcgtgaa
721 gctgacgggc tctctctccg gttggtcctc acccaaagat gtgatcctga aggtggcagg
781 catcctcacg gtgaaaggtg gcacaggtgc aatcgtggaa taccacgggc ctggtgtaga
841 ctccatctcc tgcactggca tggcgacaat ctgcaacatg ggtgcagaaa ttggggccac
901 cacttccgtg ttcccttaca accacaggat gaagaagtac ctgagcaaga ccggccggga
961 agacattgcc aatctagctg atgaattcaa ggatcacttg gtgcctgacc ctggctgcca
1021 ttatgaccaa ctaattgaaa ttaacctcag tgagctgaag ccacacatca atgggccctt
1081 cacccctgac ctggctcacc ctgtggcaga agtgggcaag gtggcagaga aggaaggatg
1141 gcctctggac atccgagtgg gtctaattgg tagctgcacc aattcaagct atgaagatat
1201 ggggcgctca gcagctgtgg ccaagcaggc actggcccat ggcctcaagt gcaagtccca
1261 gttcaccatc actccaggtt ccgagcagat ccgcgccacc attgagcggg acggctatgc
1321 acagatcttg agggatctgg gtggcattgt cctggccaat gcttgtggcc cctgcattgg
1381 ccagtgggac aggaaggaca tcaagaaggg ggagaagaac acaatcgtca cctcctacaa
1441 caggaacttc acgggccgca acgacgcaaa ccccgagacc catgcctttg tcacgtcccc
1501 agagattgtc acagccctgg ccattgcggg aaccctcaag ttcaacccag agaccgacta
1561 cctgacgggc acggatggca agaagttcag gctggaggct ccggatgcag atgagcttcc
1621 caaaggggag tttgacccag ggcaggacac ctaccagcac ccacccaagg acagcagcgg
1681 gcagcatgtg gacgtgagcc ccaccagcca gcgcctgcag ctcctggagc cttttgacaa
1741 gtgggatggc aaggacctgg aggacctgca gatcctcatc aaggtcaaag ggaagtgtac
1801 cactgaccac atctcagctg ctggcccctg gctcaagttc cgtgggcact tggataacat
1861 ctccaacaac ctgctcattg gtgccatcaa cattgaaaac ggcaaggcca actccgtgcg
1921 caatgccgtc actcaggagt ttggccccgt ccctgacact gcccgctact acaagaaaca
1981 tggcatcagg tgggtggtga tcggagacga gaactacggc gagggctcga gccgggagca
2041 tgcagctctg gagcctcgcc accttggggg ccgggccatc atcaccaaga gctttgccag
2101 gatccacgag accaacctga agaaacaggg cctgctgcct ctgaccttcg ctgacccggc
2161 tgactacaac aagattcacc ctgtggacaa gctgaccatt cagggcctga aggacttcac
2221 ccctggcaag cccctgaagt gcatcatcaa gcaccccaac gggacccagg agaccatcct
2281 cctgaaccac accttcaacg agacgcagat tgagtggttc cgcgctggca gtgccctcaa
2341 cagaatgaag gaactgcaac agtgagggca gtgcctcccc gccccgccgc tggcgtcaag
2401 ttcagctcca cgtgtgccat cagtggatcc gatccgtcca gccatggctt cctattccaa
2461 gatggtgtga ccagacatgc ttcctgctcc ccgcttagcc cacggagtga ctgtggttgt
2521 ggtggggggg ttcttaaaat aactttttag cccccgtctt cctattttga gtttggttca
2581 gatcttaagc agctccatgc aactgtattt atttttgatg acaagactcc catctaaagt
2641 ttttctcctg cctgatcatt tcattggtgg ctgaaggatt ctagagaacc ttttgttctt
2701 gcaaggaaaa caagaatcca aaaccagaaa aaaaaaaaaa aaaaaaa
//