LOCUS BC013868 2502 bp mRNA linear HUM 04-NOV-2003
DEFINITION Homo sapiens potassium channel tetramerisation domain containing 3,
mRNA (cDNA clone IMAGE:3842456), partial cds.
ACCESSION BC013868
VERSION BC013868.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2502)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2502)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (07-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC013868.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 14 Row: c Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 27545449.
FEATURES Location/Qualifiers
source 1..2502
/db_xref="H-InvDB:HIT000088214"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3842456"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..>2502
/gene="KCTD3"
/gene_synonym="NY-REN-45"
/db_xref="GeneID:51133"
CDS 295..>2502
/gene="KCTD3"
/gene_synonym="NY-REN-45"
/codon_start=1
/product="KCTD3 protein"
/protein_id="AAH13868.1"
/db_xref="GeneID:51133"
/translation="MAGGHCGSVPAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFF
SSLLSGRISTLRDETGAIFIDRDPAAFAPILNFLRTKELDLRGVSINVLRHEAEFYGI
TPLVRRLLLCEELERSSCGSVLFHGYLPPPGIPSRKINNTVRSADSRNGLNSTEGEAR
GNGTQPVLSGTGEETVRLGFPVDPRKVLIVAGHHNWIVAAYAHFAVCYRIKESSGWQQ
VFTSPYLDWTIERVALNAKVVGGPHGDKDKMVAVASESSIILWSVQDGGSGSEIGVFS
LGVPVDALFFIGNQLVATSHTGKVGVWNAVTQHWQVQDVVPITSYDTAGSFLLLGCNN
GSIYYIDMQKFPLRMKDNDLLVTELYHDPSNDAITALSVYLTPKTSVSGNWIEIAYGT
SSGAVRVIVQHPETVGSGPQLFQTFTVHRSPVTKIMLSEKHLVSVCADNNHVRTWTVT
RFRGMISTQPGSTPLASFKILSLEETESHGSYSSGNDIGPFGERDDQQVFIQKVVPIT
NKLFVRLSSTGKRICEIQAVDCTTISSFTVRECEGSSRMGSRPRRYLFTGHTNGSIQM
WDLTTAMDMVNKSEDKDVGGPTEEELLKLLDQCDLSTSRCATPNISPATSVVQHSHLR
ESNSSLQLQHHDTTHEAATYGSMRPYRESPLLARARRTESFHSYRDFQTINLNRNVER
AVPENGNLGPIQAEVKGATGECNISERKSPGVEIKKKKKKKKKKKKKKKKKKKK"
misc_feature 349..612
/gene="KCTD3"
/gene_synonym="NY-REN-45"
/note="K_tetra; Region: K+ channel tetramerisation domain.
The N-terminal, cytoplasmic tetramerisation domain (T1) of
voltage-gated K+ channels encodes molecular determinants
for subfamily-specific assembly of alpha-subunits into
functional tetrameric channels. It is distantly related to
the BTB/POZ domain pfam00651"
/db_xref="CDD:pfam02214"
BASE COUNT 717 a 540 c 651 g 594 t
ORIGIN
1 gtcggtggca gcggagcacg gagaagaggc ccgggcggcc cggcggcctg gaggccgcga
61 aaggtggagg ccgggccgcc cttgtgcacc gcaggattga cccgggaagg ggcagaagct
121 agcgagcccc gcccggccgc cgggaaggtg ggggaagccc cgtgcacccc ccgccctccg
181 gccgccgccg ccccgctggc cctgcagccg tcgccgctgc ctcgggctac agccccgggc
241 tcggcggtcc cggctgggga aggagggcgg cgagcgcgtc cggagccgcc ggagatggcg
301 ggagggcact gcggcagcgt ccccgcggcg gcggccggca gcggcgagat cgtccaactg
361 aacgtagggg ggaccagatt tagtacctca agacaaactc ttatgtggat tccagattct
421 tttttttcca gtttgctgag tgggagaatt tcaacacttc gagatgaaac tggtgctata
481 tttattgata gagatccagc agcatttgca cccattttaa attttcttcg gacaaaagaa
541 ctagacttaa ggggagtgag tattaatgtt ctcaggcatg aagcagaatt ttacgggatc
601 actccattag taagaaggct tctcttatgt gaagaattgg agcgttcctc ttgtggcagt
661 gtcctttttc atggttactt gcccccacca ggtattccta gtcgtaaaat aaacaacaca
721 gtcagatctg ctgattctag gaatggtcta aattctacag aaggtgaagc ccggggaaat
781 ggtacacagc ctgttctctc tggaacggga gaagaaactg ttaggctagg atttcctgtg
841 gatccacgaa aggtgctaat agtagctggc catcacaact ggattgtagc tgcatatgcc
901 cattttgctg tgtgttacag aatcaaagaa tcttcaggat ggcagcaagt gtttacgagc
961 ccatatttgg attggactat cgaacgagta gctttaaatg caaaggtggt tggagggcca
1021 catggagaca aagacaaaat ggttgctgtt gcctcagaga gtagcatcat cttgtggagt
1081 gttcaggatg ggggaagtgg aagtgaaatt ggagtgttca gcctgggtgt tcctgtagat
1141 gctctcttct ttattggtaa ccagttggtg gccacgagtc atacagggaa agtgggagtg
1201 tggaatgctg tcactcagca ctggcaggtt caagatgttg ttcctataac tagttatgac
1261 actgctggat cattccttct gcttggatgt aacaatggat caatatatta catagatatg
1321 cagaagttcc ccttgcgaat gaaagataat gatcttcttg taactgaact gtatcatgat
1381 ccttcaaatg atgctattac tgctctgagt gtttacctca cacccaaaac aagtgtcagt
1441 ggtaactgga tcgagatcgc ctatggtacg agctctggag cagtacgagt gattgtacaa
1501 cacccagaga cagttgggtc aggtcctcag ctttttcaga ctttcacagt tcaccgaagt
1561 cccgtaacaa aaatcatgct atcagagaag catcttgtat cagtctgtgc agataataat
1621 catgtccgga cgtggacagt aacacgattc agaggaatga tctctactca gccaggttct
1681 actcctttag cgtcattcaa gatactatcc ctggaggaga cagaaagtca tggtagctat
1741 tcctctggaa atgacatagg accttttgga gagcgagacg atcaacaggt gtttatccag
1801 aaagttgttc ccatcaccaa caaactattt gtaagactct catcgactgg aaaaagaata
1861 tgtgagatcc aggctgttga ctgtactaca atatcctcat ttacagtgag ggaatgtgag
1921 ggatccagta ggatgggctc aagaccaagg cgctacttgt tcacaggcca tacaaatggc
1981 agtattcaaa tgtgggatct gaccactgct atggatatgg ttaacaaaag tgaagataag
2041 gatgtaggtg gtccaaccga agaagagcta ctcaaattac tcgatcaatg tgatttgagc
2101 acatctcgct gtgctactcc taacatcagt ccagcaactt ccgtagttca gcatagccac
2161 ttacgagaat caaattctag ccttcagctt cagcaccatg ataccaccca tgaagcagct
2221 acttacggtt ccatgaggcc ttacagagaa agtcctttat tagcaagggc aagaaggact
2281 gagagctttc acagttatag ggacttccag actattaatt tgaacagaaa tgtagaaaga
2341 gctgtccctg aaaatggtaa cttgggtcca atacaagctg aagtgaaagg ggcaacaggg
2401 gaatgtaata tatctgagag aaagtctcct ggagtagaaa taaaaaaaaa aaaaaaaaaa
2461 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//