LOCUS BC013590 2651 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens eukaryotic translation initiation factor 2B, subunit 5
epsilon, 82kDa, mRNA (cDNA clone MGC:9947 IMAGE:3876105), complete
cds.
ACCESSION BC013590
VERSION BC013590.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2651)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2651)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-SEP-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 14 Row: a Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33667022.
FEATURES Location/Qualifiers
source 1..2651
/db_xref="H-InvDB:HIT000036296"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9947 IMAGE:3876105"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_68"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2651
/gene="EIF2B5"
/gene_synonym="CACH"
/gene_synonym="CLE"
/gene_synonym="EIF-2B"
/gene_synonym="EIF2Bepsilon"
/gene_synonym="LVWM"
/db_xref="GeneID:8893"
/db_xref="HGNC:HGNC:3261"
/db_xref="MIM:603945"
CDS 51..2216
/gene="EIF2B5"
/gene_synonym="CACH"
/gene_synonym="CLE"
/gene_synonym="EIF-2B"
/gene_synonym="EIF2Bepsilon"
/gene_synonym="LVWM"
/codon_start=1
/product="eukaryotic translation initiation factor 2B,
subunit 5 epsilon, 82kDa"
/protein_id="AAH13590.1"
/db_xref="GeneID:8893"
/db_xref="HGNC:HGNC:3261"
/db_xref="MIM:603945"
/translation="MAAPVVAPPGVVVSRANKRSGAGPGGSGGGGARGAEEEPPPPLQ
AVLVADSFDRRFFPISKDQPRVLLPLANVALIDYTLEFLTATGVQETFVFCCWKAAQI
KEHLLKSKWCRPTSLNVVRIITSELYRSLGDVLRDVDAKALVRSDFLLVYGDVISNIN
ITRALEEHRLRRKLEKNVSVMTMIFKESSPSHPTRCHEDNVVVAVDSTTNRVLHFQKT
QGLRRFAFPLSLFQGSSDGVEVRYDLLDCHISICSPQVAQLFTDNFDYQTRDDFVRGL
LVNEEILGNQIHMHVTAKEYGARVSNLHMYSAVCADVIRRWVYPLTPEANFTDSTTQS
CTHSRHNIYRGPEVSLGHGSILEENVLLGSGTVIGSNCFITNSVIGPGCHIGDNVVLD
QTYLWQGVRVAAGAQIHQSLLCDNAEVKERVTLKPRSVLTSQVVVGPNITLPEGSVIS
LHPPDAEEDEDDGEFSDDSGADQEKDKVKMKGYNPAEVGAAGKGYLWKAAGMNMEEEE
ELQQNLWGLKINMEEESESESEQSMDSEEPDSRGGSPQMDDIKVFQNEVLGTLQRGKE
ENISCDNLVLEINSLKYAYNVSLKEVMQVLSHVVLEFPLQQMDSPLDSSRYCALLLPL
LKAWSPVFRNYIKRAADHLEALAAIEDFFLEHEALGISMAKVLMAFYQLEILAEETIL
SWFSQRDTTDKGQQLRKNQQLQRFIQWLKEAEEESSEDD"
BASE COUNT 705 a 623 c 737 g 586 t
ORIGIN
1 tgcgtgcggt ggcagcttcc ttgcggaagt ggtgaccgtg agagaagaag atggcggccc
61 ctgtagtggc gccgcctggt gtggtggtta gtcgggctaa caagcgcagc ggcgcggggc
121 cgggaggcag cggtggcggg ggagccagag gggcggagga ggaaccgccg ccgcccctac
181 aagcagttct ggtggccgat agcttcgatc gccgcttctt ccccatctcc aaggaccagc
241 ctcgggtcct cttgcccctg gccaatgtgg cattaattga ctacactctg gaattcctga
301 ctgccacagg tgtacaggaa acatttgtct tttgttgctg gaaagctgct caaatcaaag
361 aacatttact gaagtcaaag tggtgccgcc ctacatctct caatgtggtt cgaataatta
421 catcagagct ctatcgatca ctgggagatg tcctccgtga tgttgatgcc aaggctttgg
481 tgcgctctga ctttcttctg gtgtatgggg atgtcatctc aaacatcaat atcaccagag
541 cccttgagga acacaggttg agacggaagc tagaaaaaaa tgtttctgtg atgacgatga
601 tcttcaagga gtcatccccc agccacccaa ctcgttgcca cgaagacaat gtggtagtgg
661 ctgtggatag taccacaaac agggttctcc attttcagaa gacccagggt ctccggcgtt
721 ttgcatttcc tctgagcctg tttcagggca gtagtgatgg agtggaggtt cgatatgatt
781 tactggattg tcatatcagc atctgttctc ctcaggtggc acaactcttt acagacaact
841 ttgactacca aactcgagat gactttgtgc gaggtctctt agtgaatgag gagatcctag
901 ggaaccagat ccacatgcac gtaacagcta aggaatatgg tgcccgtgtc tccaacctac
961 acatgtactc agctgtctgt gctgacgtca tccgccgatg ggtctaccct ctcaccccag
1021 aggcgaactt cactgacagc accacccaga gctgcactca ttcccggcac aacatctacc
1081 gagggcctga ggtcagcctg ggccatggca gcatcctaga ggaaaatgtg ctcctgggct
1141 ctggcactgt cattggcagc aattgcttta tcaccaacag tgtcattggc cccggctgcc
1201 acattggtga taacgtggtg ctggaccaga cctacctgtg gcagggtgtt cgagtggcgg
1261 ctggagcaca gatccatcag tctctgcttt gtgacaatgc tgaggtcaag gaacgagtga
1321 cactgaaacc acgctctgtc ctcacttccc aggtggtcgt gggcccaaat atcacgctgc
1381 ctgagggctc ggtgatctct ttgcaccctc cagatgcaga ggaagatgaa gatgatggcg
1441 agttcagtga tgattctggg gctgaccaag aaaaggacaa agtgaagatg aaaggttaca
1501 atccagcaga agtaggagct gctggcaagg gctacctctg gaaagctgca ggcatgaaca
1561 tggaggaaga ggaggaactg cagcagaatc tgtggggact caagatcaac atggaagaag
1621 agagtgaaag tgaaagtgag caaagtatgg attctgagga gccggacagc cggggaggct
1681 cccctcagat ggatgacatc aaagtgttcc agaatgaagt tttaggaaca ctacagcggg
1741 gcaaagagga gaacatttct tgtgacaatc tcgtcctgga aatcaactct ctcaagtatg
1801 cctataacgt aagtctaaag gaggtgatgc aggtactgag ccacgtggtc ctggagttcc
1861 ccctgcaaca gatggattcc ccgcttgact caagccgcta ctgtgccctg ctgcttcctc
1921 tgctaaaggc ctggagccct gtttttagga actacataaa gcgcgcagcc gaccatttgg
1981 aagcgttagc agccattgag gacttcttcc tagagcatga agctcttggt atttccatgg
2041 ccaaggtact gatggctttc taccagctgg agatcctggc tgaggaaaca attctgagct
2101 ggttcagcca aagagataca actgacaagg gccagcagtt gcgcaagaat caacagctgc
2161 agaggttcat ccagtggcta aaagaggcag aagaggagtc atctgaagat gactgaagtc
2221 acactgcctg ctcctttggg tgtgattgag tgccctcctg gctcctgggc tgggacaagt
2281 gaggaactag ctgcagaggg atgagtgacc accatccagg ctgagactga aaggagcaga
2341 ggctggaact acagtattct ttcccctgct agcaaccatg tgcctcccat cctgactgtg
2401 gagttgggat gtggaagtgg ggctggaaca aagcttctgc ctagggagga gctaagcagg
2461 cccggcagtt ggaggaaggc cagaggaaca gctttgtgct ccggctttcc ctcagggaac
2521 agcagagagc agttggctct ttctgctgct tgtatatgtt aatattaaaa gagagtggtg
2581 taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
2641 aaaaaaaaaa a
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