LOCUS BC013200 2182 bp mRNA linear HUM 01-SEP-2006
DEFINITION Homo sapiens lymphocyte-specific protein tyrosine kinase, mRNA
(cDNA clone MGC:17196 IMAGE:4341278), complete cds.
ACCESSION BC013200
VERSION BC013200.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2182)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2182)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (27-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 26 Row: j Column: 21
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 20428651.
FEATURES Location/Qualifiers
source 1..2182
/db_xref="H-InvDB:HIT000036178"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17196 IMAGE:4341278"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2182
/gene="LCK"
/gene_synonym="p56lck"
/gene_synonym="pp58lck"
/gene_synonym="YT16"
/db_xref="GeneID:3932"
/db_xref="HGNC:HGNC:6524"
/db_xref="MIM:153390"
CDS 101..1720
/gene="LCK"
/gene_synonym="p56lck"
/gene_synonym="pp58lck"
/gene_synonym="YT16"
/codon_start=1
/product="LCK protein"
/protein_id="AAH13200.1"
/db_xref="GeneID:3932"
/db_xref="HGNC:HGNC:6524"
/db_xref="MIM:153390"
/translation="MGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGSEV
RDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQS
LTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTA
GSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCT
RLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLK
QGSMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENDTLLDSQLEEKGL
GASPWGNLGQQLLLLPTGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIH
RDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWK
ERPEDRPTFDYLRSVLEDFFTATEGQYQPQP"
BASE COUNT 495 a 611 c 616 g 460 t
ORIGIN
1 gagggctcag agggagcacc ggtttggagc tgggaccccc tattttagct tttctgtggc
61 tggtgaatgg ggatcccagg atctcacaat ctcagggacc atgggctgtg gctgcagctc
121 acacccggaa gatgactgga tggaaaacat cgatgtgtgt gagaactgcc attatcccat
181 agtcccactg gatggcaagg gcacgctgct catccgaaat ggctctgagg tgcgggaccc
241 actggttacc tacgaaggct ccaatccgcc ggcttcccca ctgcaagaca acctggttat
301 cgctctgcac agctatgagc cctctcacga cggagatctg ggctttgaga agggggaaca
361 gctccgcatc ctggagcaga gcggcgagtg gtggaaggcg cagtccctga ccacgggcca
421 ggaaggcttc atccccttca attttgtggc caaagcgaac agcctggagc ccgaaccctg
481 gttcttcaag aacctgagcc gcaaggacgc ggagcggcag ctcctggcgc ccgggaacac
541 tcacggctcc ttcctcatcc gggagagcga gagcaccgcg ggatcgtttt cactgtcggt
601 ccgggacttc gaccagaacc agggagaggt ggtgaaacat tacaagatcc gtaatctgga
661 caacggtggc ttctacatct cccctcgaat cacttttccc ggcctgcatg aactggtccg
721 ccattacacc aatgcttcag atgggctgtg cacacggttg agccgcccct gccagaccca
781 gaagccccag aagccgtggt gggaggacga gtgggaggtt cccagggaga cgctgaagct
841 ggtggagcgg ctgggggctg gacagttcgg ggaggtgtgg atggggtact acaacgggca
901 cacgaaggtg gcggtgaaga gcctgaagca gggcagcatg tccccggacg ccttcctggc
961 cgaggccaac ctcatgaagc agctgcaaca ccagcggctg gttcggctct acgctgtggt
1021 cacccaggag cccatctaca tcatcactga atacatggag aatgacacac ttctagactc
1081 ccagttggag gagaaaggtc tgggggcctc cccctggggc aacttgggcc agcaactctt
1141 gcttctgccc acagggagtc tagtggattt tctcaagacc ccttcaggca tcaagttgac
1201 catcaacaaa ctcctggaca tggcagccca aattgcagaa ggcatggcat tcattgaaga
1261 gcggaattat attcatcgtg accttcgggc tgccaacatt ctggtgtctg acaccctgag
1321 ctgcaagatt gcagactttg gcctagcacg cctcattgag gacaacgagt acacagccag
1381 ggagggggcc aagtttccca ttaagtggac agcgccagaa gccattaact acgggacatt
1441 caccatcaag tcagatgtgt ggtcttttgg gatcctgctg acggaaattg tcacccacgg
1501 ccgcatccct tacccaggga tgaccaaccc ggaggtgatt cagaacctgg agcgaggcta
1561 ccgcatggtg cgccctgaca actgtccaga ggagctgtac caactcatga ggctgtgctg
1621 gaaggagcgc ccagaggacc ggcccacctt tgactacctg cgcagtgtgc tggaggactt
1681 cttcacggcc acagagggcc agtaccagcc tcagccttga gaggccttga gaggccctgg
1741 ggttctcccc ctttctctcc agcctgactt ggggagatgg agttcttgtg ccatagtcac
1801 atggcctatg cacatatgga ctctgcacat gaatcccacc cacatgtgac acatatgcac
1861 cttgtgtctg tacacgtgtc ctgtagttgc gtggactctg cacatgtctt gtacatgtgt
1921 agcctgtgca tgtatgtctt ggacactgta caaggtaccc ctttctggct ctcccatttc
1981 ctgagaccac agagagaggg gagaagcctg ggattgacag aagcttctgc ccacctactt
2041 ttctttcctc agatcatcca gaagttcctc aagggccagg actttatcta atacctctgt
2101 gtgctcctcc ttggtgcctg gcctggcaca catcaggagt tcaataaatg tctgttgatg
2161 actgttaaaa aaaaaaaaaa aa
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