LOCUS BC013145 3157 bp mRNA linear HUM 04-OCT-2003
DEFINITION Homo sapiens TBC1 domain family, member 5, mRNA (cDNA clone
MGC:21104 IMAGE:4510019), complete cds.
ACCESSION BC013145
VERSION BC013145.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3157)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3157)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (27-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 28 Row: h Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 7661997.
FEATURES Location/Qualifiers
source 1..3157
/db_xref="H-InvDB:HIT000036148"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:21104 IMAGE:4510019"
/tissue_type="Testis, embryonal carcinoma"
/clone_lib="NIH_MGC_92"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3157
/gene="TBC1D5"
/gene_synonym="KIAA0210"
/db_xref="GeneID:9779"
CDS 178..2565
/gene="TBC1D5"
/gene_synonym="KIAA0210"
/codon_start=1
/product="TBC1D5 protein"
/protein_id="AAH13145.1"
/db_xref="GeneID:9779"
/translation="MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSS
TLDSEGTFNSYRKEWEELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDK
SQWISRIEELRAWYSNIKEIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELR
SMIEQDVKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLH
CDHQAFLHASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGK
ETLMTPIPFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRW
VRLLFGREFPLQDLLVVWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCLGLL
MHYPFIGDVHSLILKALFLRDPKRNPRPVTYQFHPNLDYYKARGADLMNKSRTNAKGA
PLNINKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTSAEAPSHHL
QQQQQQQRLMKSESMPVQLNKGLSSKNISSSPSVESLPGGREFTGSPPSSATKKDSFF
SNISRSRSHSKTMGRKESEEELEAQISFLQGQLNDLDAMCKYCAKVMDTHLVNIQDVI
LQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQLEAEENEQITIADNHYCSSGQGQ
GRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISKDDDGSSARGSFSGQAQPLRT
LRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDDSSKDSGFTIVSPLDI"
misc_feature 412..1329
/gene="TBC1D5"
/gene_synonym="KIAA0210"
/note="TBC; Region: Domain in Tre-2, BUB2p, and Cdc16p.
Probable Rab-GAPs. Widespread domain present in Gyp6 and
Gyp7, thereby giving rise to the notion that it performs a
GTP-activator activity on Rab-like GTPases"
/db_xref="CDD:smart00164"
BASE COUNT 934 a 759 c 685 g 779 t
ORIGIN
1 agcccttctg cgccacagag atggggtctc actctgtcat ccaggctgga atatagtggc
61 acaatcatag cccattgtag cctccatctc aaggactcag gggatcctcc cttctaggcc
121 tcccaagtag ctgggattac aggtagttac ttttggtgac gctgtccagt tcccacaatg
181 tatcattcct tatctgaaac tagacatcct ctgcagccag aagaacaaga agtaggcatt
241 gaccccttgt ccagttactc taacaagtct ggaggagatt caaataaaaa tggaagaaga
301 acaagttcta ctttagactc tgaagggact tttaattcct ataggaaaga atgggaagaa
361 ctatttgtaa acaacaatta cttggcaaca ataaggcaga aggggattaa tgggcagctg
421 agaagcagca ggttccgcag catttgctgg aagctatttc tttgtgttct tcctcaagac
481 aaaagtcaat ggataagtag aattgaagaa ttaagagcat ggtatagcaa cattaaagaa
541 atacatatta ccaacccgag gaaggttgtt ggccaacaag atttgatgat caataatcct
601 ctttcacagg atgaagggag tctttggaac aaattcttcc aagataaaga acttcgatca
661 atgattgaac aagatgtcaa aagaacgttt cctgaaatgc agtttttcca gcaagaaaat
721 gtgagaaaaa ttcttacaga tgttcttttc tgttatgcca gagaaaacga gcagttgctt
781 tataaacagg gcatgcacga actgttagca cctatagtct ttgtccttca ctgtgaccac
841 caagcttttc tacatgccag tgagtctgca cagcccagtg aggaaatgaa aactgtcttg
901 aaccctgagt atctggaaca tgatgcctat gcagtgttct cacaacttat ggaaactgct
961 gaaccttggt tttcaacttt tgagcatgat ggtcagaagg ggaaagaaac actgatgact
1021 cccattccct ttgctagacc acaagattta gggccaacaa ttgctattgt tactaaagtc
1081 aaccagatcc aggatcatct actgaagaag catgatattg agctttacat gcacttgaac
1141 agactagaaa ttgcaccaca gatatatggg ttaaggtggg tgcggctgct atttggacga
1201 gagttccccc tgcaggacct tctggtggtc tgggatgcct tgtttgcaga cggcctcagc
1261 ctgggtttag tagattatat cttcgtagcc atgttacttt acatccgaga tgctttgatc
1321 tctagtaact accagacctg tctcggcctt ctgatgcatt acccattcat cggggatgta
1381 cactcactga ttcttaaggc tctgttcctt agagatccaa agagaaatcc aagaccagtg
1441 acttatcaat tccatccaaa tttagattat tacaaagcac gaggagcaga cctcatgaat
1501 aaaagccgga ccaatgccaa aggtgctccc ctgaatataa ataaggtctc taatagcctg
1561 attaattttg gaagaaagtt gatttcccca gcaatggctc caggcagtgc aggtggccct
1621 gtacctggag gcaacagcag tagctcctcc tctgttgtaa ttcctaccag gacctcagca
1681 gaggccccaa gccatcactt gcaacagcaa cagcagcagc agaggctgat gaaatcagaa
1741 agcatgcctg tgcaattgaa caaagggcta agttctaaaa acatcagttc atctccaagc
1801 gttgagagtt tgcctggagg aagagaattc actggctctc caccttcatc tgctactaaa
1861 aaagattcct tttttagcaa catctcacgt tctcgctcac acagcaaaac tatgggcaga
1921 aaagaatctg aagaagaatt agaagcccaa atttccttcc ttcaagggca gttgaatgac
1981 ctggatgcca tgtgcaaata ctgtgcaaag gtgatggaca ctcatcttgt aaatattcaa
2041 gatgtgatat tacaagaaaa tttggaaaaa gaagatcaaa ttctggtttc cctggcagga
2101 ttaaaacaga tcaaagacat tctaaaaggt tccctgcgtt ttaaccagag ccagctagag
2161 gccgaagaga acgaacagat caccattgcg gacaaccact actgctccag cggccagggc
2221 cagggccgag gccaaggcca gagcgttcaa atgtcagggg ccattaaaca ggcctcttca
2281 gaaacgccag ggtgcactga tagagggaat tccgatgact tcatcctgat ttccaaagat
2341 gatgatggga gcagtgccag gggctccttc tccggccagg cccagcctct tcgcaccctc
2401 agaagcacct ctgggaaaag ccaggcccca gtctgctccc cactggtgtt ctcagatcca
2461 ctgatgggcc cagcctcagc ttcctccagc aaccccagct ccagtcctga tgacgacagc
2521 agcaaggact ctggcttcac cattgtgagt cccctggaca tctgaccaca gtgcccagtc
2581 ctgccccaca gggatctagc cacccttcag tggccccaag gccagactga ggctcatcca
2641 gtggagaacc ttcttaaacc actgcttcct tcccggcatg cattttgcat tggtccagcc
2701 ctttgaaacc ccttagagag aagcatatat ggccacaaag cacagaggct taggtttgcc
2761 acatgcagac agggctttct gggcccttac ctaatcccca cccgactctt gctctgagtt
2821 agagctgagt tacgtaccca gtatcacact cacagttaga aaagaccgaa tcacaattta
2881 gaatcacttt tcctctgtcc ccttctcccc agctaagaat gtgtggcacc tccatcagtt
2941 atacttagaa ggagcagaaa tagttatttt cgtatcttct atccctcaaa gcatcagaca
3001 tgggaaaatt ggtttatacc aagaaagctt cctctgtgga aatctgtctc agcctacttt
3061 attcctgcat tgggaagcca tatcgcagag ctaaatgcaa tagaatgaac cagaactagt
3121 ggattccagg gctgggggaa aaaaaaaaaa aaaaaaa
//