LOCUS BC012899 2327 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens sialidase 4, mRNA (cDNA clone MGC:18222
IMAGE:4156395), complete cds.
ACCESSION BC012899
VERSION BC012899.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2327)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2327)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (20-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: d Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 18152772.
FEATURES Location/Qualifiers
source 1..2327
/db_xref="H-InvDB:HIT000036023"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:18222 IMAGE:4156395"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2327
/gene="NEU4"
/gene_synonym="MGC18222"
/db_xref="GeneID:129807"
/db_xref="HGNC:HGNC:21328"
/db_xref="MIM:608527"
CDS 452..1942
/gene="NEU4"
/gene_synonym="MGC18222"
/codon_start=1
/product="sialidase 4"
/protein_id="AAH12899.2"
/db_xref="GeneID:129807"
/db_xref="HGNC:HGNC:21328"
/db_xref="MIM:608527"
/translation="MMSSAAFPRWLSMGVPRTPSRTVLFERERTGLTYRVPSLLPVPP
GPTLLAFVEQRLSPDDSHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPV
HDAGTGTVFLFFIAVLGHTPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIG
GAVQDWATFAVGPGHGVQLPSGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHG
RTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAE
RVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAV
DPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLY
SHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYSDLASIGPAPEGGLVFACL
YESGARTSYDEISFCTFSLREVLENVPASPKPPNLGDKPRGCCWPS"
BASE COUNT 343 a 784 c 795 g 405 t
ORIGIN
1 agcccagcga ggcctgtgct gcgaggggct gtgctgtgcc aggggaggcc ccgcacccgg
61 gaagcccaga ggagagtgtg cactcacgga gccctcctgg cagggccgcg tctctggagc
121 agcagacccg tgtccctctg ggaggtcaac tgcggcctca cagctgggcc tgtcccagca
181 cagcccttgt tggagggcgc acccccgtgt cctcagcacc ccagtgttga gtgcattgac
241 ctgcagaggg gagcctgtgc tggtcccggg cgtctgtgtg gctcctgggt gcccatctgc
301 acccctggcc ctgctctggg cttcagtgga gccgtgccac cgtgggagtg tccagggtcc
361 tgacgtagcc ctgagacgtg gccagctccc tggcctgctg cccgcacagt gggcccttgt
421 ctctgctctg ggtcaggcga ggcagccacc catgatgagc tctgcagcct tcccaaggtg
481 gctgagcatg ggggtccctc gtaccccttc acggacagtg ctcttcgagc gggagaggac
541 gggcctgacc taccgcgtgc cctcgctgct ccccgtgccc cccgggccca ccctgctggc
601 ctttgtggag cagcggctca gccctgacga ctcccacgcc caccgcctgg tgctgaggag
661 gggcacgctg gccgggggct ccgtgcggtg gggtgccctg cacgtgctgg ggacagcagc
721 cctggcggag caccggtcca tgaacccctg ccctgtgcac gatgctggca cgggcaccgt
781 cttcctcttc ttcatcgcgg tgctgggcca cacgcctgag gccgtgcaga tcgccacggg
841 aaggaacgcc gcgcgcctct gctgtgtggc cagccgtgac gccggcctct cgtggggcag
901 cgcccgggac ctcaccgagg aggccatcgg tggtgccgtg caggactggg ccacattcgc
961 tgtgggtccc ggccacggcg tgcagctgcc ctcaggccgc ctgctggtac ccgcctacac
1021 ctaccgcgtg gaccgccgag agtgttttgg caagatctgc cggaccagcc ctcactcctt
1081 cgccttctac agcgatgacc acggccgcac ctggcgctgt ggaggcctcg tgcccaacct
1141 gcgctcaggc gagtgccagc tggcggcggt ggacggtggg caggccggca gcttcctcta
1201 ctgcaatgcc cggagcccac tgggcagccg tgtgcaggcg ctcagcactg acgagggcac
1261 ctccttcctg cccgcagagc gcgtggcttc cctgcccgag actgcctggg gctgccaggg
1321 cagcatcgtg ggcttcccag cccccgcccc caacaggcca cgggatgaca gttggtcagt
1381 gggccccggg agtcccctcc agcctccact cctcggtcct ggagtccacg aacccccaga
1441 ggaggctgct gtagaccccc gtggaggcca ggtgcctggt gggcccttca gccgtctgca
1501 gcctcggggg gatggcccca ggcagcctgg ccccaggcct ggggtcagtg gggatgtggg
1561 gtcctggacc ctggcactcc ccatgccctt tgctgccccg ccccagagcc ccacgtggct
1621 gctgtactcc cacccagtgg ggcgcagggc tcggctacac atgggtatcc gcctgagcca
1681 gtccccgctg gacccgcgca gctggacaga gccctgggtg atctacgagg gccccagcgg
1741 ctactccgac ctggcgtcca tcgggccggc tcctgagggg ggcctggttt ttgcctgcct
1801 gtacgagagc ggggccagga cctcctatga tgagatttcc ttttgtacat tctccctgcg
1861 tgaggtcctg gagaacgtgc ccgccagccc caagccgccc aaccttgggg acaagcctcg
1921 ggggtgctgc tggccctcct gacaggcctt ctggccgtgc ccatgcccct tgggtgcctg
1981 gggcagaggg gtggaatacg ttggggtgcc ccacgatagc tgtggggggg gctcttagtg
2041 caagatcctg tggattagaa acaagttgct cctcagagct ctcaagcagg gactgctctt
2101 taggaagggg agcagcggct gggagtgagc agggcagggt gggggcaggg tgggggcacg
2161 aagtgggccc tgggtgaccc ccacagctcc cttccgaggc tgcagggcca ggcgcgggac
2221 cgcaggtagc ccagggtgtt gtgggtggca gcacttgttt actggctgct ttctggctcg
2281 aaataaagga atcgtgcttg tgaaaaaaaa aaaaaaaaaa aaaaaaa
//