LOCUS BC012844 2431 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens prion protein, mRNA (cDNA clone MGC:8899
IMAGE:3863784), complete cds.
ACCESSION BC012844
VERSION BC012844.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2431)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2431)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (20-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 21 Row: i Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 34335269.
FEATURES Location/Qualifiers
source 1..2431
/db_xref="H-InvDB:HIT000035991"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8899 IMAGE:3863784"
/tissue_type="Ovary, adenocarcinoma"
/clone_lib="NIH_MGC_66"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2431
/gene="PRNP"
/gene_synonym="ASCR"
/gene_synonym="CD230"
/gene_synonym="prion"
/gene_synonym="PrP"
/gene_synonym="PrP27-30"
/gene_synonym="PrP33-35C"
/gene_synonym="PrPc"
/db_xref="GeneID:5621"
/db_xref="HGNC:HGNC:9449"
/db_xref="MIM:176640"
CDS 48..809
/gene="PRNP"
/gene_synonym="ASCR"
/gene_synonym="CD230"
/gene_synonym="prion"
/gene_synonym="PrP"
/gene_synonym="PrP27-30"
/gene_synonym="PrP33-35C"
/gene_synonym="PrPc"
/codon_start=1
/product="prion protein"
/protein_id="AAH12844.1"
/db_xref="GeneID:5621"
/db_xref="HGNC:HGNC:9449"
/db_xref="MIM:176640"
/translation="MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSP
GGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKP
SKPKTNMKHMAGAAAAGAVVGGLGGYVLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQ
VYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQY
ERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG"
BASE COUNT 680 a 500 c 578 g 673 t
ORIGIN
1 cgcggcgccg cgagcttctc ctctcctcac gaccgagagc agtcattatg gcgaaccttg
61 gctgctggat gctggttctc tttgtggcca catggagtga cctgggcctc tgcaagaagc
121 gcccgaagcc tggaggatgg aacactgggg gcagccgata cccggggcag ggcagccctg
181 gaggcaaccg ctacccacct cagggcggtg gtggctgggg gcagcctcat ggtggtggct
241 gggggcagcc tcatggtggt ggctgggggc agccccatgg tggtggctgg ggacagcctc
301 atggtggtgg ctggggtcaa ggaggtggca cccacagtca gtggaacaag ccgagtaagc
361 caaaaaccaa catgaagcac atggctggtg ctgcagcagc tggggcagtg gtggggggcc
421 ttggcggcta cgtgctggga agtgccatga gcaggcccat catacatttc ggcagtgact
481 atgaggaccg ttactatcgt gaaaacatgc accgttaccc caaccaagtg tactacaggc
541 ccatggatga gtacagcaac cagaacaact ttgtgcacga ctgcgtcaat atcacaatca
601 agcagcacac ggtcaccaca accaccaagg gggagaactt caccgagacc gacgttaaga
661 tgatggagcg cgtggttgag cagatgtgta tcacccagta cgagagggaa tctcaggcct
721 attaccagag aggatcgagc atggtcctct tctcctctcc acctgtgatc ctcctgatct
781 ctttcctcat cttcctgata gtgggatgag gaaggtcttc ctgttttcac catctttcta
841 atctttttcc agcttgaggg aggcggtatc cacctgcagc ccttttagtg gtggtgtctc
901 actctttctt ctctctttgt cccggatagg ctaatcaata cccttggcac tgatgggcac
961 tggaaaacat agagtagacc tgagatgctg gtcaagcccc ctttgattga gttcatcatg
1021 agccgttgct aatgccaggc cagtaaaagt ataacagcaa ataaccattg gttaatctgg
1081 acttattttt ggacttagtg caacaggttg aggctaaaac aaatctcaga acagtctgaa
1141 atacctttgc ctggatacct ctggctcctt cagcagctag agctcagtat actaatgccc
1201 tatcttagta gagatttcat agctatttag agatattttc cattttaaga aaacccgaca
1261 acatttctgc caggtttgtt aggaggccac atgatactta ttcaaaaaaa tcctagagat
1321 tcttagctct tgggatgcag gctcagcccg ctggagcatg agctctgtgt gtaccgagaa
1381 ctggggtgat gttttacttt tcacagtatg ggctacacag cagctgttca acaagagtaa
1441 atattgtcac aacactgaac ctctggctag aggacatatt cacagtgaac ataactgtaa
1501 catatatgaa aggcttctgg gacttgaaat caaatgtttg ggaatggtgc ccttggaggc
1561 aacctcccat tttagatgtt taaaggaccc tatatgtggc attcctttct ttaaactata
1621 ggtaattaag gcagctgaaa agtaaattgc cttctagaca ctgaaggcaa atctcctttg
1681 tccatttacc tggaaaccag aatgattttg acatacagga gagctgcagt tgtgaaagca
1741 ccatcatcat agaggatgat gtaattaaaa aatggtcagt gtgcaaagaa aagaactgct
1801 tgcatttctt tatttctgtc tcataattgt caaaaaccag aattaggtca agttcatagt
1861 ttctgtaatt ggcttttgaa tcaaagaata gggagacaat ctaaaaaata tcttaggttg
1921 gagatgacag aaatatgatt gatttgaagt ggaaaaagaa attctgttaa tgttaattaa
1981 agtaaaatta ttccctgaat tgtttgatat tgtcacctag cagatatgta ttacttttct
2041 gcaatgttat tattggcttg cactttgtga gtattctatg taaaaatata tatgtatata
2101 aaatatatat tgcataggac agacttagga gttttgttta gagcagttaa catctgaagt
2161 gtctaatgca ttaacttttg taaggtactg aatacttaat atgtgggaaa cccttttgcg
2221 tggtccttag gcttacaatg tgcactgaat cgtttcatgt aagaatccaa agtggacacc
2281 attaacaggt ctttgaaata tgcatgtact ttatattttc tatatttgta actttgcatg
2341 ttcttgtttt gttatataaa aaaattgtaa atgtttaata tctgactgaa attaaacgag
2401 cgaagatgag caccacaaaa aaaaaaaaaa a
//