LOCUS BC012619 1654 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens reticulon 4, mRNA (cDNA clone IMAGE:4082756), complete
cds.
ACCESSION BC012619
VERSION BC012619.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1654)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1654)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 19 Row: d Column: 8
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 47519489
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1654
/db_xref="H-InvDB:HIT000035906"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4082756"
/tissue_type="Brain, glioblastoma"
/clone_lib="NIH_MGC_57"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1654
/gene="RTN4"
/gene_synonym="ASY"
/gene_synonym="Nbla00271"
/gene_synonym="Nbla10545"
/gene_synonym="NI220/250"
/gene_synonym="NOGO"
/gene_synonym="NOGO-A"
/gene_synonym="NSP"
/gene_synonym="NSP-CL"
/gene_synonym="RTN-X"
/gene_synonym="RTN4-A"
/gene_synonym="RTN4-B1"
/gene_synonym="RTN4-B2"
/gene_synonym="RTN4-C"
/db_xref="GeneID:57142"
/db_xref="HGNC:HGNC:14085"
/db_xref="MIM:604475"
CDS 156..1277
/gene="RTN4"
/gene_synonym="ASY"
/gene_synonym="Nbla00271"
/gene_synonym="Nbla10545"
/gene_synonym="NI220/250"
/gene_synonym="NOGO"
/gene_synonym="NOGO-A"
/gene_synonym="NSP"
/gene_synonym="NSP-CL"
/gene_synonym="RTN-X"
/gene_synonym="RTN4-A"
/gene_synonym="RTN4-B1"
/gene_synonym="RTN4-B2"
/gene_synonym="RTN4-C"
/codon_start=1
/product="reticulon 4"
/protein_id="AAH12619.1"
/db_xref="GeneID:57142"
/db_xref="HGNC:HGNC:14085"
/db_xref="MIM:604475"
/translation="MEDLDQSPLVSSSDSPPRPQPAFKYQFVREPEDEEEEEEEEEED
EDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRGPLPAAPPVAP
ERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPPPPASVSPQAEPVWT
PPAPAPAAPPSTPAAPKRRGSSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIV
SVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSA
LGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPV
IYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGLKRKAE"
BASE COUNT 371 a 466 c 437 g 380 t
ORIGIN
1 ggggattgtt ccgggagccg tcaccacagt aggtccctcg gctcagtcgg cccagcccct
61 ctcagtcctc cccaaccccc acaaccgccc gcggctctga gacgcggccc cggcggcggc
121 ggcagcagct gcagcatcat ctccaccctc cagccatgga agacctggac cagtctcctc
181 tggtctcgtc ctcggacagc ccaccccggc cgcagcccgc gttcaagtac cagttcgtga
241 gggagcccga ggacgaggag gaagaagagg aggaggaaga ggaggacgag gacgaagacc
301 tggaggagct ggaggtgctg gagcggaagc ccgccgccgg gctgtccgcg gccccagtgc
361 ccaccgcccc tgccgccggc gcgcccctga tggacttcgg aaatgacttc gtgccgccgg
421 cgccccgggg acccctgccg gccgctcccc ccgtcgcccc ggagcggcag ccgtcttggg
481 acccgagccc ggtgtcgtcg accgtgcccg cgccatcccc gctgtctgct gccgcagtct
541 cgccctccaa gctccctgag gacgacgagc ctccggcccg gcctccccct cctcccccgg
601 ccagcgtgag cccccaggca gagcccgtgt ggaccccgcc agccccggct cccgccgcgc
661 ccccctccac cccggccgcg cccaagcgca ggggctcctc gggctcagtg gttgttgacc
721 tcctgtactg gagagacatt aagaagactg gagtggtgtt tggtgccagc ctattcctgc
781 tgctttcatt gacagtattc agcattgtga gcgtaacagc ctacattgcc ttggccctgc
841 tctctgtgac catcagcttt aggatataca agggtgtgat ccaagctatc cagaaatcag
901 atgaaggcca cccattcagg gcatatctgg aatctgaagt tgctatatct gaggagttgg
961 ttcagaagta cagtaattct gctcttggtc atgtgaactg cacgataaag gaactcaggc
1021 gcctcttctt agttgatgat ttagttgatt ctctgaagtt tgcagtgttg atgtgggtat
1081 ttacctatgt tggtgccttg tttaatggtc tgacactact gattttggct ctcatttcac
1141 tcttcagtgt tcctgttatt tatgaacggc atcaggcaca gatagatcat tatctaggac
1201 ttgcaaataa gaatgttaaa gatgctatgg ctaaaatcca agcaaaaatc cctggattga
1261 agcgcaaagc tgaatgaaaa cgcccaaaat aattagtagg agttcatctt taaaggggat
1321 attcatttga ttatacgggg gagggtcagg gaagaacgaa ccttgacgtt gcagtgcagt
1381 ttcacagatc gttgttagat ctttattttt agccatgcac tgttgtgagg aaaaattacc
1441 tgtcttgact gccatgtgtt catcatctta agtattgtaa gctgctatgt atggatttaa
1501 accgtaatca tatctttttc ctatctaatc tatctgaggc actggtggaa taaaaaacct
1561 gtatatttta ctttgttgca gatagtcttg ccgcatcttg gcaagttgca gagatggtgg
1621 agcgaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
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