LOCUS BC012584 1897 bp mRNA linear HUM 04-OCT-2003
DEFINITION Homo sapiens chaperonin containing TCP1, subunit 8 (theta), mRNA
(cDNA clone MGC:13491 IMAGE:4133182), complete cds.
ACCESSION BC012584
VERSION BC012584.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1897)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1897)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (15-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 19 Row: g Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 6005726.
FEATURES Location/Qualifiers
source 1..1897
/db_xref="H-InvDB:HIT000050565"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:13491 IMAGE:4133182"
/tissue_type="Bone marrow, chronic myelogenous leukemia"
/clone_lib="NIH_MGC_54"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1897
/gene="CCT8"
/gene_synonym="Cctq"
/gene_synonym="D21S246"
/gene_synonym="KIAA0002"
/db_xref="GeneID:10694"
CDS 228..1721
/gene="CCT8"
/gene_synonym="Cctq"
/gene_synonym="D21S246"
/gene_synonym="KIAA0002"
/codon_start=1
/product="CCT8 protein"
/protein_id="AAH12584.1"
/db_xref="GeneID:10694"
/translation="MNKMVINHLEKLFVTNDAATILRELEVQHPAAKMIVMASHMQEQ
EVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYEIACRKAHEILPNLVCCSAKN
LRDIDEVSSLLRTSIMSKQYGNEVFLAKLIAQACVSIFPDSGHFNVDNIRVCKILGSG
ISSSSVLHGMVFKKETEGDVTSVKDAKIAVYSCPFDGMITETKGTVLIKTAEELMNFS
KGEENLMDAQVKAIADTGANVVVTGGKVADMALHYANKYNIMLVRLNSKWDLRRLCKT
VGATALPRLTPPVLEEMGHCDSVYLSEVGDTQVVVFKHEKEDGAISTIVLRGSTDNLM
DDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAKQITSYGETCPGLEQYAIKKFAE
AFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLDIEAEVPAVKDMLEAGILDTY
LGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKDWDDDQND"
misc_feature 228..1655
/gene="CCT8"
/gene_synonym="Cctq"
/gene_synonym="D21S246"
/gene_synonym="KIAA0002"
/note="cpn60_TCP1; Region: TCP-1/cpn60 chaperonin family.
This family includes members from the HSP60 chaperone
family and the TCP-1 (T-complex protein) family"
/db_xref="CDD:pfam00118"
BASE COUNT 597 a 330 c 447 g 523 t
ORIGIN
1 gggggcggtc ttccgagcgg tcgcgtgaac tgcttcctgc aggctggcca tggcgcttca
61 cgttcccaag gctccgggct ttgcccagat gctcaaggag ggagcgaaag taagggctga
121 aggaaaggaa tgagcacttt tcaggattag aagaggctgt gtatagaaac atacaagctt
181 gcaaggagct tgcccaaacc actcgtacag catatggacc aaatggaatg aacaaaatgg
241 ttatcaacca cttggagaag ttgtttgtga caaacgatgc agcaactatt ttaagagaac
301 tagaagtaca gcatcctgct gcaaaaatga ttgtaatggc ttctcatatg caagagcaag
361 aagttggaga tggcacaaac tttgttctgg tatttgctgg agctctcctg gaattagctg
421 aagaacttct gaggattggc ctgtcagttt cagaggtcat agaaggttat gaaatagcct
481 gcagaaaagc tcatgagatt cttcctaatt tggtatgttg ttctgcaaaa aaccttcgag
541 atattgatga agtctcatct ctacttcgta cctccataat gagtaaacaa tatggtaatg
601 aagtatttct ggccaagctt attgctcagg catgcgtatc tatttttcct gattccggcc
661 atttcaatgt tgataacatc agagtttgta aaattctggg ctctggtatc agttcctctt
721 cagtattgca tggcatggtt tttaagaagg aaaccgaagg tgatgtaaca tctgtcaaag
781 atgcaaaaat agcagtgtac tcttgtcctt ttgatggcat gataacagaa actaagggaa
841 cagtgttgat aaagactgct gaagaattga tgaattttag taagggagaa gaaaacctca
901 tggatgcaca agtcaaagct attgctgata ctggtgcaaa tgtcgtagta acaggtggca
961 aagtggcaga catggctctt cattatgcaa ataaatataa tatcatgtta gtgaggctaa
1021 actcaaaatg ggatctccga agactttgta aaactgttgg tgctacagct cttcctagat
1081 tgacacctcc tgtccttgaa gaaatgggac actgtgacag tgtttacctc tcagaagttg
1141 gagatactca ggtggtggtt tttaagcatg aaaaggaaga tggcgccatt tctaccatag
1201 tacttcgagg ctctacagac aatctgatgg atgacataga aagggcagta gacgatggtg
1261 ttaatacttt caaagttctt acaagggata aacgtcttgt acccggaggt ggagcaacag
1321 aaattgaatt agccaaacag atcacatcat atggagagac atgtcctgga cttgaacagt
1381 atgctattaa gaagtttgct gaggcatttg aagctattcc ccgcgcactg gcagaaaact
1441 ctggagttaa ggccaatgaa gtaatctcta aactttatgc agtacatcaa gaaggaaata
1501 aaaacgttgg attagatatt gaggctgaag tccctgctgt aaaggacatg ctggaagctg
1561 gtattctaga tacttacctg ggaaaatatt gggctatcaa actcgctact aatgctgcag
1621 tcactgtact tagagtggat cagatcatca tggcaaaacc agctggtggg cccaagcctc
1681 caagtgggaa gaaagactgg gatgatgacc aaaatgattg aaattggctt aatttttact
1741 gtaggtgaag gctgtatttg tagtagtact caagaatcac ctgatgtttt cttattctcc
1801 ttaaattaag agttattttg tgtttgtatt cttggctgga tgttataata aacatattgt
1861 tactgtcaaa aaaaaaaaaa aaaaaaaaaa aaaaaaa
//