LOCUS BC012566 1331 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens nucleophosmin (nucleolar phosphoprotein B23,
numatrin), mRNA (cDNA clone MGC:13433 IMAGE:4097025), complete cds.
ACCESSION BC012566
VERSION BC012566.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1331)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1331)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: CLONTECH Laboratories, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 19 Row: e Column: 16.
FEATURES Location/Qualifiers
source 1..1331
/db_xref="H-InvDB:HIT000035875"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:13433 IMAGE:4097025"
/tissue_type="Bone marrow, chronic myelogenous leukemia"
/clone_lib="NIH_MGC_54"
/lab_host="DH10B"
/note="Vector: pDNR-LIB"
gene 1..1331
/gene="NPM1"
/gene_synonym="B23"
/gene_synonym="NPM"
/db_xref="GeneID:4869"
/db_xref="HGNC:HGNC:7910"
/db_xref="MIM:164040"
CDS 101..985
/gene="NPM1"
/gene_synonym="B23"
/gene_synonym="NPM"
/codon_start=1
/product="nucleophosmin (nucleolar phosphoprotein B23,
numatrin)"
/protein_id="AAH12566.1"
/db_xref="GeneID:4869"
/db_xref="HGNC:HGNC:7910"
/db_xref="MIM:164040"
/translation="MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSL
RTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRL
KCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAA
DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSS
TPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCF
RMTDQEAIQDFWQWRKSL"
BASE COUNT 452 a 224 c 315 g 340 t
ORIGIN
1 ggggccctgg tgtgattccg tcctgcgcgg ttgttctctg gagcagcgtt cttttatctc
61 cgtccgcctt ctctcctacc taagtgcgtg ccgccacccg atggaagatt cgatggacat
121 ggacatgagc cccctgaggc cccagaacta tcttttcggt tgtgaactaa aggccgacaa
181 agattatcac tttaaggtgg ataatgatga aaatgagcac cagttatctt taagaacggt
241 cagtttaggg gctggtgcaa aggatgagtt gcacattgtt gaagcagagg caatgaatta
301 cgaaggcagt ccaattaaag taacactggc aactttgaaa atgtctgtac agccaacggt
361 ttcccttggg ggctttgaaa taacaccacc agtggtctta aggttgaagt gtggttcagg
421 gccagtgcat attagtggac agcacttagt agctgtggag gaagatgcag agtcagaaga
481 tgaagaggag gaggatgtga aactcttaag tatatctgga aagcggtctg cccctggagg
541 tggtagcaag gttccacaga aaaaagtaaa acttgctgct gatgaagatg atgacgatga
601 tgatgaagag gatgatgatg aagatgatga tgatgatgat tttgatgatg aggaagctga
661 agaaaaagcg ccagtgaaga aatctatacg agatactcca gccaaaaatg cacaaaagtc
721 aaatcagaat ggaaaagact caaaaccatc atcaacacca agatcaaaag gacaagaatc
781 cttcaagaaa caggaaaaaa ctcctaaaac accaaaagga cctagttctg tagaagacat
841 taaagcaaaa atgcaagcaa gtatagaaaa aggtggttct cttcccaaag tggaagccaa
901 attcatcaat tatgtgaaga attgcttccg gatgactgac caagaggcta ttcaagattt
961 ctggcagtgg aggaagtctc tttaagaaaa tagtttaaac aatttgttaa aaaattttcc
1021 gtcttatttc atttctgtaa cagttgatat ctggctgtcc tttttataat gcagagtgag
1081 aactttccct accgtgtttg ataaatgttg tccaggttct attgccaaga atgtgttgtc
1141 caaaatgccg tttagttttt aaagatggaa ctccaccctt tgcttggttt taagtatgta
1201 tggaatgtta tgataggaca tagtagtagc ggtggtcaga catggaaatg gtggggagac
1261 aaaaatatac atgtgaaata aaactcagta ttttaataaa ataaaaaaaa aaaaaaaaaa
1321 aaaaaaaaaa a
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