LOCUS BC012337 2868 bp mRNA linear HUM 09-MAY-2005
DEFINITION Homo sapiens hexokinase domain containing 1, mRNA (cDNA clone
IMAGE:4563921), partial cds.
ACCESSION BC012337
VERSION BC012337.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2868)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2868)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 29 Row: g Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33342275.
FEATURES Location/Qualifiers
source 1..2868
/db_xref="H-InvDB:HIT000087827"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4563921"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2868
/gene="HKDC1"
/gene_synonym="FLJ22761"
/gene_synonym="FLJ37767"
/db_xref="GeneID:80201"
CDS <1..2036
/gene="HKDC1"
/gene_synonym="FLJ22761"
/gene_synonym="FLJ37767"
/codon_start=3
/product="HKDC1 protein"
/protein_id="AAH12337.1"
/db_xref="GeneID:80201"
/translation="DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLG
SLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAM
EKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLREN
KKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTA
VASRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYV
CGLPDGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELF
DHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDV
VDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMR
NIEMVEGGEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMY
LGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQL
GLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLY
KLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGAALITAVAKRLQQAQKEN"
BASE COUNT 710 a 654 c 865 g 639 t
ORIGIN
1 aggacatgag caacattgac ctggtggagg gcgacgaggg caggatgtgc atcaacacag
61 agtggggggc cttcggggac gacggggccc tggaggacat tcgcactgag ttcgacaggg
121 agctggacct cggctctctc aacccaggaa agcaactgtt cgagaagatg atcagtggcc
181 tgtacctggg ggagcttgtc aggcttatct tgctgaagat ggccaaggct ggcctcctgt
241 ttggtggtga gaaatcttct gctctccaca ctaagggcaa gatcgaaaca cggcacgtgg
301 ctgccatgga gaagtataaa gaaggccttg ctaatacaag agagatcctg gtggacctgg
361 gtctggaacc gtctgaggct gactgcattg ccgtccagca tgtctgtacc atcgtctcct
421 tccgctcggc caatctctgt gcagcagctc tggcggccat cctgacacgc ctccgggaga
481 acaagaaggt ggaacggctc cggaccacag tgggcatgga cggcaccctc tacaagatac
541 accctcagta cccaaaacgc ctgcacaagg tggtgaggaa actggtccca agctgtgatg
601 tccgcttcct cctgtcagag agtggcagca ccaagggggc cgccatggtg accgcggtgg
661 cctcccgcgt gcaggcccag cggaagcaga tcgacagggt gctggctttg ttccagctga
721 cccgagagca gctcgtggac gtgcaggcca agatgcgggc tgagctggag tatgggctga
781 agaagaagag ccacgggctg gccacggtca ggatgctgcc cacctacgtc tgcgggctgc
841 cggacggcac agagaaagga aagtttctcg ccctggatct tgggggaacc aacttccggg
901 tcctcctggt gaagatcaga agtggacgga ggtcagtgcg aatgtacaac aagatcttcg
961 ccatccccct ggagatcatg cagggcactg gtgaggagct ctttgatcac attgtgcagt
1021 gcatcgccga cttcctggac tacatgggcc tcaagggagc ctccctacct ttgggcttca
1081 cattctcatt tccctgcagg cagatgagca ttgacaaggg aacactcata gggtggacca
1141 aaggtttcaa ggccactgac tgtgaagggg aggacgtggt ggacatgctc agggaagcca
1201 tcaagaggag aaacgagttt gacctggaca ttgttgcagt cgtgaatgat acagtgggga
1261 ccatgatgac ctgtggctat gaagatccta attgtgagat tggcctgatt gcaggaacag
1321 gcagcaacat gtgctacatg gaggacatga ggaacatcga gatggtggag gggggtgaag
1381 ggaagatgtg catcaataca gagtggggag gatttggaga caatggctgc atagatgaca
1441 tccggacccg atacgacacg gaggtggatg aggggtcctt gaatcctggc aagcagagat
1501 acgagaaaat gaccagtggg atgtacttgg gggagattgt gcggcagatc ctgatcgacc
1561 tgaccaagca gggtctcctc ttccgagggc agatttcaga gcgtctccgg accaggggca
1621 tcttcgaaac caagttcctg tcccagatcg aaagcgatcg gctggccctt ctccaggtca
1681 ggaggattct gcagcagctg ggcctggaca gcacgtgtga ggacagcatc gtggtgaagg
1741 aggtgtgcgg agccgtgtcc cggcgggcgg cccagctctg cggtgctggc ctggccgcta
1801 tagtggaaaa aaggagagaa gaccaggggc tagagcacct gaggatcact gtgggtgtgg
1861 acggcaccct gtacaagctg caccctcact tttctagaat attgcaggaa actgtgaagg
1921 aactagcccc tcgatgtgat gtgacattca tgctgtcaga agatggcagt ggaaaagggg
1981 cagcactgat cactgctgtg gccaagaggt tacagcaggc acagaaggag aactaggaac
2041 ccctgggatt ggacctgatg catcttggat actgaacagc ttttcctctg gcagatcagt
2101 tggtcagaga ccaatgggca ccctcctggc tgacctcacc ttctggatgg ccgaaagaga
2161 accccaggtt ctcgggtact cttagtatct tgtactggat ttgcagtgac attacatgac
2221 atctctattt ggtatatttg ggccaaaatg ggccaactta tgaaatcaaa gtgtctgtcc
2281 tgagagatcc cctttcaaca cattgttcag gtgaggcttg agctgtcaat tctctatggc
2341 tttcagtctt gtggctgcgg gacttggaaa tatatagaat ctgcccatgt ggctggcagg
2401 ctgtttcccc attgggatgc ttaagccatc tcttataggg gattggaccc tgtacttgtg
2461 gatgaacatt ggagagcaag aggaactcac gttatgaact agggggatct catctaactt
2521 gtccttaact tgccatgttg acttcaaacc tgttaagaga acaaagactt tgaagtatcc
2581 agccccaggg tgcagagagg ttgattgcca gggagcactg caggaatcat tgcatgctta
2641 aagcgagtta tgtcagcacc ctgtaggatt ttgttcctta ttaagtgtgt gccatgtggt
2701 ggggtgctgt ctggggcatc tgtttttcat tttgcctgtg gtttgtgttg caggtgttga
2761 tagttgtttt aaggattgtt aggtatagga aatccagtaa attaataaaa aaattttgat
2821 tttccaataa actttgcaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//