LOCUS BC012140 1496 bp mRNA linear HUM 04-OCT-2003
DEFINITION Homo sapiens Bernardinelli-Seip congenital lipodystrophy 2
(seipin), mRNA (cDNA clone MGC:20240 IMAGE:4564181), complete cds.
ACCESSION BC012140
VERSION BC012140.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1496)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1496)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 29 Row: g Column: 18.
FEATURES Location/Qualifiers
source 1..1496
/db_xref="H-InvDB:HIT000035688"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20240 IMAGE:4564181"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1496
/gene="BSCL2"
/gene_synonym="GNG3LG"
/gene_synonym="MGC4694"
/gene_synonym="SEIPIN"
/db_xref="GeneID:26580"
/db_xref="MIM:606158"
CDS 189..1385
/gene="BSCL2"
/gene_synonym="GNG3LG"
/gene_synonym="MGC4694"
/gene_synonym="SEIPIN"
/codon_start=1
/product="BSCL2 protein"
/protein_id="AAH12140.1"
/db_xref="GeneID:26580"
/db_xref="MIM:606158"
/translation="MVNDPPVPALLWAQEVGQVLAGRARRLLLQFGVLFCTILLLLWV
SVFLYGSFYYSYMPTVSHLSPVHFYYRTDCDSSTTSLCSFPVANVSLTKGGRDRVLMY
GQPYRVTLELELPESPVNQDLGMFLVTISCYTRGGRIISTSSRSVMLHYRSDLLQMLD
TLVFSSLLLFGFAEQKQLLEVELYADYRENSYVPTTGAIIEIHSKRIQLYGAYLRIHA
HFTGLRYLLYNFPMTCAFIGVASNFTFLSVIVLFSYMQWVWGGIWPRHRFSLQVNIRK
RDNSRKEVQRRISAHQPGPEGQEESTPQSDVTEDGESPEDPSGTEGQLSEEEKPDQQP
LSGEEELEPEASDGSGSWEDAALLTEANLPAPAPASASAPVLETLGSSEPAGGALRQR
PTCSSS"
BASE COUNT 306 a 451 c 394 g 345 t
ORIGIN
1 cacggttgcc cccagcgcgc gaggctggtg agtcggcagc cctgtggcag ccggcgggct
61 ggtttccatg gttgcacgat taggaaccac cagctgctgc atcccatggc caggggtggc
121 gtccaggtgg cagagcagct aggaacgcaa ggcctgaacc tggggccaga caccctgctc
181 tcccggccat ggtcaacgac cctccagtac ctgccttact gtgggcccag gaggtgggcc
241 aagtcttggc aggccgtgcc cgcaggctgc tgctgcagtt tggggtgctc ttctgcacca
301 tcctcctttt gctctgggtg tctgtcttcc tctatggctc cttctactat tcctatatgc
361 cgacagtcag ccacctcagc cctgtgcatt tctactacag gaccgactgt gattcctcca
421 ccacctcact ctgctccttc cctgttgcca atgtctcgct gactaagggt ggacgtgatc
481 gggtgctgat gtatggacag ccgtatcgtg ttaccttaga gcttgagctg ccagagtccc
541 ctgtgaatca agatttgggc atgttcttgg tcaccatttc ctgctacacc agaggtggcc
601 gaatcatctc cacttcttcg cgttcggtga tgctgcatta ccgctcagac ctgctccaga
661 tgctggacac actggtcttc tctagcctcc tgctatttgg ctttgcagag cagaagcagc
721 tgctggaggt ggaactctac gcagactata gagagaactc gtacgtgccg accactggag
781 cgatcattga gatccacagc aagcgcatcc agctgtatgg agcctacctc cgcatccacg
841 cgcacttcac tgggctcaga tacctgctat acaacttccc gatgacctgc gccttcatag
901 gtgttgccag caacttcacc ttcctcagcg tcatcgtgct cttcagctac atgcagtggg
961 tgtggggggg catctggccc cgacaccgct tctctttgca ggttaacatc cgaaaaagag
1021 acaattcccg gaaggaagtc caacgaagga tctctgctca tcagccaggg cctgaaggcc
1081 aggaggagtc aactccgcaa tcagatgtta cagaggatgg tgagagccct gaagatccct
1141 cagggacaga gggtcagctg tctgaggagg agaaaccaga tcagcagccc ctgagcggag
1201 aagaggagct agagcctgag gccagtgatg gttcaggctc ctgggaagat gcagctttgc
1261 tgacggaggc caacctgcct gctcctgctc ctgcttctgc ttctgcccct gtcctagaga
1321 ctctgggcag ctctgaacct gctgggggtg ctctccgaca gcgccccacc tgctctagtt
1381 cctgaagaaa aggggcagac tcctcacatt ccagcacttt cccacctgac tcctctcccc
1441 tcgtttttcc ttcaataaac tattttgtgt cagcttcaaa aaaaaaaaaa aaaaaa
//