LOCUS BC012105 2496 bp mRNA linear HUM 04-OCT-2003
DEFINITION Homo sapiens nuclear VCP-like, mRNA (cDNA clone MGC:20090
IMAGE:4636004), complete cds.
ACCESSION BC012105
VERSION BC012105.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2496)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2496)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 29 Row: j Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4505482.
FEATURES Location/Qualifiers
source 1..2496
/db_xref="H-InvDB:HIT000035662"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20090 IMAGE:4636004"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2496
/gene="NVL"
/db_xref="GeneID:4931"
/db_xref="MIM:602426"
CDS 241..2220
/gene="NVL"
/codon_start=1
/product="NVL protein"
/protein_id="AAH12105.1"
/db_xref="GeneID:4931"
/db_xref="MIM:602426"
/translation="MEDYPDPQDSKDSSLLESDMKRKGKLKNKGSKRKKEDLQEVDGE
IEAVLQKKAKARGLEFQISNVKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPR
GVLLHGPPGCGKTLLAHAIAGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNA
PCIIFIDEIDAITPKREVASKDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDS
LDPALRRAGRFDREICLGIPDEASRERILQTLCRKLRLPQAFDFCHLAHLTPGFVGAD
LMALCREAAMCAVNRVLMKLQEQQKKNPEMEDLPSKGVQEERLGTEPTSETQDELQRL
LGLLRDQDPLSEEQMQGLCIELNDFIVALSSVQPSAKREGFVTVPNVTWADIGALEDI
REELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAVANESGLNFISVK
GPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRETGASVRVVNQL
LTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPADRLAILKTITK
NGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQKSGNEKGEL
KVSHKHFEEAFKKVRSSISKKDQIMYERLQESLSR"
misc_feature 493..2169
/gene="NVL"
/note="SpoVK; Region: ATPases of the AAA+ class
[Posttranslational modification, protein turnover,
chaperones]"
/db_xref="CDD:COG0464"
BASE COUNT 770 a 514 c 618 g 594 t
ORIGIN
1 cccagacctg cagggttcgt ggataataaa ctcaagcagc gagtcatcca gtatagacta
61 tggtcgaaga aaaagaaatg cttttaggat tcaggtagaa aaagtattta gcataattag
121 tagtgagaag gaacttaaga atttaacaga attagaagat gaacatttgg caaaaagggc
181 aagacaaggt gaagaggata atgaaggtat actgaaagct attctgatga tgattcaagt
241 atggaagact acccagatcc acaggattca aaagattctt ctcttttgga gagtgatatg
301 aaacggaaag gcaagctaaa gaataaagga agcaaaagga agaaagaaga tcttcaggaa
361 gtagatggag aaattgaagc tgtcctacaa aagaaagcta aagccagggg gttagaattc
421 cagatctcca acgtgaagtt tgaagatgtg ggaggcaatg atatgacatt aaaagaggtc
481 tgcaagatgc tcatacacat gcgtcacccg gaggtgtacc accacctggg cgtcgtgccc
541 cctcgtggag ttctccttca tggaccacca ggctgtggga agacattact tgcacatgca
601 attgctgggg aacttgacct gccaattttg aaagtggctg ctccagagat tgtgtctgga
661 gtatccggag agtctgagca gaagctgaga gaactatttg agcaagctgt gtcaaatgca
721 ccatgtatca ttttcattga tgaaattgat gctattaccc ccaaaagaga agtggcttca
781 aaagatatgg aacgaagaat tgtagcccaa ctcctaacct gcatggatga tctgaataat
841 gtggctgcta cagcccgggt cctagttatt ggagctacta atcgaccaga ctcgttagac
901 cctgctttga gacgtgcggg aaggttcgac cgagaaatat gcctaggtat cccagatgaa
961 gcatccaggg aaagaatact tcaaacattg tgcagaaaac tgaggcttcc tcaagctttt
1021 gatttctgtc acttagcaca cctaactcca ggctttgttg gtgctgatct catggcactg
1081 tgccgagagg cagcaatgtg tgcagtcaat agagtcttaa tgaagctaca ggaacagcag
1141 aagaaaaatc ctgaaatgga agatttgcca tctaaaggag tccaggagga aaggctggga
1201 actgagccca cttctgaaac acaggatgaa ttacaaaggc tgctggggtt gctaagagac
1261 caagatcccc tctcagagga gcagatgcaa ggactgtgca ttgaactgaa tgatttcatt
1321 gttgctctat cctcagtcca accctctgcc aaaagggaag gctttgtcac tgtccctaat
1381 gtgacatggg cagatattgg tgccctggaa gacattagag aggagctcac catggcaata
1441 ttggcaccag tacgcaaccc agaccagttc aaagctcttg gattggtgac tccagctggg
1501 gtcctccttg ctggtcctcc tggctgtggg aagactctgc tggcgaaggc tgttgcaaat
1561 gagtccggac taaattttat atctgtcaag ggccccgaat tactaaacat gtatgttggt
1621 gagagtgaac gtgctgtgcg acaagttttt caacgagcca agaactcagc accctgtgtg
1681 atattctttg atgaagtgga tgctttatgt cctcgaagat cagaccgaga gacaggggca
1741 agtgtccgag tggtgaatca gctacttaca gagatggatg gtctggaagc acgccagcag
1801 gtttttatta tggcagccac taacaggcca gatataattg accctgcaat cctgcgcccg
1861 ggccgcctgg acaaaacact gtttgtgggt ttaccgcccc ctgcagatcg ccttgccatc
1921 ttaaaaacta tcacaaaaaa tggtaccaaa ccaccactgg atgcagatgt aaatttggaa
1981 gcaattgctg gtgaccttcg ctgtgattgc tatacgggcg cagatctctc tgctttggta
2041 cgagaagctt ctatctgtgc cctgagacag gaaatggcaa gacagaagag tggaaatgaa
2101 aaaggtgaac tcaaggttag tcataagcat tttgaagaag ctttcaagaa agtaagatca
2161 tctatatcaa aaaaggatca aatcatgtat gaacgtttgc aggagtccct cagccggtga
2221 tgtctccagc agccggctta gaggagctag cccatcaagc cggcagagaa tcccccacac
2281 gctctgaagg acccactttc agctggacac aggcgcggcc tcatgtaaac attttatttt
2341 caaatgaatg aggccaagct gaagctgaag ctgaagattc ttcccatctg gccagccttg
2401 tgtgaaaatg ccttcttcct ctttaagaaa aaggacaatt tttaaactgc tgaaataaaa
2461 tgactgttac atttttcaaa aaaaaaaaaa aaaaaa
//