LOCUS BC012049 2799 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cytochrome P450, family 1, subfamily B, polypeptide 1,
mRNA (cDNA clone MGC:19842 IMAGE:4662252), complete cds.
ACCESSION BC012049
VERSION BC012049.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2799)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2799)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-AUG-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 29 Row: p Column: 7
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13325059.
FEATURES Location/Qualifiers
source 1..2799
/db_xref="H-InvDB:HIT000035618"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:19842 IMAGE:4662252"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_18"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2799
/gene="CYP1B1"
/gene_synonym="CP1B"
/db_xref="GeneID:1545"
/db_xref="HGNC:HGNC:2597"
/db_xref="MIM:601771"
CDS 357..1988
/gene="CYP1B1"
/gene_synonym="CP1B"
/codon_start=1
/product="cytochrome P450, family 1, subfamily B,
polypeptide 1"
/protein_id="AAH12049.1"
/db_xref="GeneID:1545"
/db_xref="HGNC:HGNC:2597"
/db_xref="MIM:601771"
/translation="MGTSLSPNDPWPLNPLSIQQTTLLLLLSVLATVHVGQRLLRQRR
RQLRSAPPGPFAWPLIGNAAAVGQAAHLSFARLARRYGDVFQIRLGSCPIVVLNGERA
IHQALVQQGSAFADRPAFASFRVVSGGRSMAFGHYSEHWKVQRRAAHSMMRNFFTRQP
RSRQVLEGHVLSEARELVALLVRGSADGAFLDPRPLTVVAVANVMSAVCFGCRYSHDD
PEFRELLSHNEEFGRTVGAGSLVDVMPWLQYFPNPVRTVFREFEQLNRNFSNFILDKF
LRHCESLRPGAAPRDMMDAFILSAEKKAAGDSHGGGARLDLENVPATITDIFGASQDT
LSTALQWLLLLFTRYPDVQTRVQAELDQVVGRDRLPCMGDQPNLPYVLAFLYEAMRFS
SFVPVTIPHATTANTSVLGYHIPKDTVVFVNQWSVNHDPVKWPNPENFDPARFLDKDG
LINKDLTSRVMIFSVGKRRCIGEELSKMQLFLFISILAHQCDFRANPNEPAKMNFSYG
LTIKPKSFKVNVTLRESMELLDSAVQNLQAKETCQ"
BASE COUNT 641 a 772 c 740 g 646 t
ORIGIN
1 gggagcgagc gcttctgcga ctccagttgt gagagccgca agggcatggg aattgacgcc
61 actcaccgac ccccagtctc aatctcaacg ctgtgaggaa acctcgactt tgccaggtcc
121 ccaagggcag cggggctcgg cgagcgaggc acccttctcc gtccccatcc caatccaagc
181 gctcctggca ctgacgacgc caagagactc gagtgggagt taaagcttcc agtgagggca
241 gcaggtgtcc aggccgggcc tgcgggttcc tgttgacgtc ttgccctagg caaaggtccc
301 agttccttct cggagccggc tgtcccgcgc cactggaaac cgcacctccc cgcagcatgg
361 gcaccagcct cagcccgaac gacccttggc cgctaaaccc gctgtccatc cagcagacca
421 cgctcctgct actcctgtcg gtgctggcca ctgtgcatgt gggccagcgg ctgctgaggc
481 aacggaggcg gcagctccgg tccgcgcccc cgggcccgtt tgcgtggcca ctgatcggaa
541 acgcggcggc ggtgggccag gcggctcacc tctcgttcgc tcgcctggcg cggcgctacg
601 gcgacgtttt ccagatccgc ctgggcagct gccccatagt ggtgctgaat ggcgagcgcg
661 ccatccacca ggccctggtg cagcagggct cggccttcgc cgaccggccg gccttcgcct
721 ccttccgtgt ggtgtccggc ggccgcagca tggctttcgg ccactactcg gagcactgga
781 aggtgcagcg gcgcgcagcc cacagcatga tgcgcaactt cttcacgcgc cagccgcgca
841 gccgccaagt cctcgagggc cacgtgctga gcgaggcgcg cgagctggtg gcgctgctgg
901 tgcgcggcag cgcggacggc gccttcctcg acccgaggcc gctgaccgtc gtggccgtgg
961 ccaacgtcat gagtgccgtg tgtttcggct gccgctacag ccacgacgac cccgagttcc
1021 gtgagctgct cagccacaac gaagagttcg ggcgcacggt gggcgcgggc agcctggtgg
1081 acgtgatgcc ctggctgcag tacttcccca acccggtgcg caccgttttc cgcgaattcg
1141 agcagctcaa ccgcaacttc agcaacttca tcctggacaa gttcttgagg cactgcgaaa
1201 gccttcggcc cggggccgcc ccccgcgaca tgatggacgc ctttatcctc tctgcggaaa
1261 agaaggcggc cggggactcg cacggtggtg gcgcgcggct ggatttggag aacgtaccgg
1321 ccactatcac tgacatcttc ggcgccagcc aggacaccct gtccaccgcg ctgcagtggc
1381 tgctcctcct cttcaccagg tatcctgatg tgcagactcg agtgcaggca gaattggatc
1441 aggtcgtggg gagggaccgt ctgccttgta tgggtgacca gcccaacctg ccctatgtcc
1501 tggccttcct ttatgaagcc atgcgcttct ccagctttgt gcctgtcact attcctcatg
1561 ccaccactgc caacacctct gtcttgggct accacattcc caaggacact gtggtttttg
1621 tcaaccagtg gtctgtgaat catgacccag tgaagtggcc taacccggag aactttgatc
1681 cagctcgatt cttggacaag gatggcctca tcaacaagga cctgaccagc agagtgatga
1741 ttttttcagt gggcaaaagg cggtgcattg gcgaagaact ttctaagatg cagctttttc
1801 tcttcatctc catcctggct caccagtgcg atttcagggc caacccaaat gagcctgcga
1861 aaatgaattt cagttatggt ctaaccatta aacccaagtc atttaaagtc aatgtcactc
1921 tcagagagtc catggagctc cttgatagtg ctgtccaaaa tttacaagcc aaggaaactt
1981 gccaataaga agcaagaggc aagctgaaat tttagaaata ttcacatctt cggagatgag
2041 gagtaaaatt cagttttttt ccagttcctc ttttgtgctg cttctcaatt agcgtttaag
2101 gtgagcataa atcaactgtc catcaggtga ggtgtgctcc atacccagcg gttcttcatg
2161 agtagtgggc tatgcaggag cttctgggag atttttttga gtcaaagact taaagggccc
2221 aatgaattat tatatacata ctgcatcttg gttatttctg aaggtagcat tctttggagt
2281 taaaatgcac atatagacac atacacccaa acacttacac caaactactg aatgaagcag
2341 tattttggta accaggccat ttttggtggg aatccaagat tggtctccca tatgcagaaa
2401 tagacaaaaa gtatattaaa caaagtttca gagtatattg ttgaagagac agagacaagt
2461 aatttcagtg taaagtgtgt gattgaaggt gataagggaa aagataaaga ccagaaattc
2521 ccttttcacc ttttcaggaa aataacttag actctagtat ttatgggtgg atttatcctt
2581 ttgccttctg gtatacttcc ttacttttaa ggataaatca taaagtcagt tgctcaaaaa
2641 gaaatcaata gttgaattag tgagtatagt ggggttccat gagttatcat gaattttaaa
2701 gtatgcatta ttaaattgta aaactccaag gtgatgttgt acctcttttg cttgccaaag
2761 tacagaattt gaattatcag caaaaaaaaa aaaaaaaaa
//