LOCUS BC012041 3845 bp mRNA linear ROD 15-JUL-2006
DEFINITION Mus musculus poly (ADP-ribose) polymerase family, member 1, mRNA
(cDNA clone MGC:6498 IMAGE:2648390), complete cds.
ACCESSION BC012041
VERSION BC012041.1
KEYWORDS MGC.
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 3845)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3845)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Gilbert Smith, Ph.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 5 Row: p Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 20806108.
FEATURES Location/Qualifiers
source 1..3845
/organism="Mus musculus"
/mol_type="mRNA"
/strain="FVB/N"
/db_xref="taxon:10090"
/clone="MGC:6498 IMAGE:2648390"
/tissue_type="Mammary tumor. Metallothionien-TGF alpha
model. 10 month old virgin mouse. Taken by biopsy."
/clone_lib="NCI_CGAP_Mam1"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3845
/gene="Parp1"
/gene_synonym="PARP"
/gene_synonym="parp-1"
/gene_synonym="PPOL"
/gene_synonym="sPARP-1"
/db_xref="GeneID:11545"
/db_xref="MGI:MGI:1340806"
CDS 60..3104
/gene="Parp1"
/gene_synonym="PARP"
/gene_synonym="parp-1"
/gene_synonym="PPOL"
/gene_synonym="sPARP-1"
/codon_start=1
/product="poly (ADP-ribose) polymerase family, member 1"
/protein_id="AAH12041.1"
/db_xref="GeneID:11545"
/db_xref="MGI:MGI:1340806"
/translation="MAEASERLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMF
DGKVPHWYHFSCFWKVGHSIRQPDVEVDGFSELRWDDQQKVKKTAEAGGVAGKGQDGS
GGKAEKTLGDFLAEYAKSNRSMCKGCLEKIEKGQMRLSKKMVDPEKPQLGMIDRWYHP
TCFVKKRDELGFRPEYSASQLKGFSLLSAEDKEALKKQLPAIKNEGKRKGDEVDGTDE
VAKKKSKKGKDKDSSKLEKALKAQNELIWNIKDELKKACSTNDLKELLIFNQQQVPSG
ESAILDRVADGMAFGALLPCKECSGQLVFKSDAYYCTGDVTAWTKCMVKTQNPSRKEW
VTPKEFREISYLKKLKVKKQDRIFPPESSAPAPLALPLSVTSAPTAVNSSAPADKPLS
NMKILTLGKLSQNKDEAKAVIEKLGGKLTGSANKASLCISTKKEVEKMSKKMEEVKAA
NVRVVCEDFLQDVSASTKSLQELLSAHSLSSWGAEVKAEPGEVVAPKGKSAAPSKKSK
GAVKEEGVNKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGT
NSYYKLQLLEDDKESRYWIFRSWGRVGTVIGSNKLEQMPSKEDAVEHFMKLYEEKTGN
AWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVKPGTKSKLPKPVQELVGMIFDVESM
KKALVEYEIDLQKMPLGKLSRRQIQAAYSILSEVQQAVSQGSSESQILDLSNRFYTLI
PHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLK
TDIKVVDRDSEEAEVIRKYVKNTHATTHNAYDLEVIDIFKIEREGESQRYKPFRQLHN
RRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGD
PIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSASITLEGVEVPLG
TGIPSGVNDTCLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW"
BASE COUNT 1042 a 930 c 1080 g 793 t
ORIGIN
1 cacgttagcg gagcgcacca gcggcggcgt cgggctgccg ctgcagcacg agaaggagga
61 tggcggaggc ctcggagagg ctttatcgag tggagtacgc gaagagcggg cgcgcctctt
121 gcaagaaatg cagcgagagt attcccaagg actccctccg catggccatc atggtgcagt
181 cacccatgtt cgatgggaaa gtcccacact ggtaccactt ctcctgcttc tggaaggtgg
241 gccactccat ccggcagcct gatgttgagg tggatggctt ctctgagctg cgctgggatg
301 atcagcagaa ggtcaagaag acggccgagg ctggaggcgt ggcaggcaaa ggccaggatg
361 gaagtggcgg caaggcggag aagacattgg gtgacttttt agcggagtac gccaagtcca
421 acaggagcat gtgcaagggc tgcctggaga agatagagaa gggccagatg cgcctgtcca
481 agaagatggt ggatccagag aagccacagc tgggtatgat tgaccgctgg taccatccaa
541 cttgctttgt caagaagcgg gacgagctgg gcttccggcc tgagtacagt gccagtcagc
601 tcaagggctt tagcctcctc tctgcagaag acaaagaagc tctgaagaag cagctcccgg
661 ccatcaagaa tgaaggaaag agaaaaggtg acgaggtgga tggaacagat gaagtggcca
721 aaaagaaatc taagaaaggg aaggacaagg atagtagtaa gctggagaag gccctcaagg
781 ctcagaatga gctgatctgg aatatcaaag acgagctgaa gaaagcgtgt tccaccaacg
841 acctgaagga gctgctcatc ttcaaccagc agcaggtgcc gtcaggagag tcagcgatct
901 tggacagagt tgctgacggc atggcgtttg gggcccttct gccctgcaag gagtgttcag
961 gccagctggt ctttaagagc gacgcttatt actgtactgg ggatgtcact gcctggacca
1021 agtgcatggt caagacacag aatcctagcc gaaaggaatg ggtaactcca aaggaattcc
1081 gagaaatatc ctacctcaag aagttaaagg tcaaaaaaca ggaccgaata ttccctccag
1141 aaagcagcgc cccagcacca ctggcactgc ccctctctgt cacctcagca cccacagctg
1201 tgaactcctc tgctccagca gacaagcccc tgtctaacat gaagatcctg actcttggga
1261 agctctccca gaacaaggac gaagcaaaag ctgtgattga gaaactcgga ggcaagttga
1321 caggatctgc caacaaggcc tccttgtgta tcagcactaa aaaggaggtg gagaagatga
1381 gtaagaagat ggaggaagtg aaagcggcca acgttcgagt tgtgtgtgag gacttcctcc
1441 aggacgtgtc tgcctccact aaaagcctcc aagagctgct ctcggcccac agcttgtcct
1501 cgtggggggc tgaggtgaag gcagagcctg gtgaagtggt ggcccccaag gggaagtcag
1561 ctgcaccctc caagaagagc aagggtgctg tcaaggagga aggtgtcaac aaatctgaaa
1621 agaggatgaa attaactctg aagggaggag cagccgttga tcctgactct ggtctggaac
1681 actctgcaca cgtcctggag aaaggtggga aggtgttcag cgccacactt ggcctggtgg
1741 acattgtgaa agggacgaac tcctattaca aactgcagct tctggaggac gacaaggaga
1801 gcaggtactg gatcttccgg tcctggggcc gggtgggcac agttatcggc agtaacaaac
1861 ttgagcagat gccctccaaa gaggacgctg ttgagcactt catgaagctg tatgaagaga
1921 agactgggaa tgcctggcac tcgaaaaact tcacaaagta tcccaagaag ttctaccctc
1981 tggagattga ctatggccag gacgaagagg cagtaaagaa gctgacggtg aagcctggca
2041 ccaagtcgaa gctgccgaag ccagtgcagg agctcgtggg gatgatcttc gacgtggaga
2101 gcatgaaaaa ggccttggtg gagtacgaga ttgacctcca gaagatgccc ttggggaagc
2161 tgagcagaag gcagatccag gccgcctact ctatcctcag cgaggtccag caggcagtgt
2221 ctcaaggcag cagtgaatcc cagatcctag atctctccaa tcgcttctac actctgatcc
2281 cccatgactt tggaatgaag aagcccccac tcctgaacaa cgcagacagc gtgcaggcca
2341 aggtggagat gctagacaac ctcctggaca tcgaggtggc ctatagtctt ctcaggggtg
2401 gctctgacga cagcagcaag gatcccatcg acgtcaacta cgagaaactc aaaactgaca
2461 ttaaggtggt tgacagagat tctgaagagg ccgaggtcat caggaagtac gtgaagaaca
2521 ctcatgctac cacgcacaac gcctatgacc tggaagtgat cgatatcttc aagatagagc
2581 gcgaggggga gagccagcgc tacaagccct tcaggcagct tcacaaccgg aggctgctgt
2641 ggcacggctc caggaccacc aactttgctg gcatcctgtc gcagggtctg cggatagccc
2701 cacctgaagc gcctgtgaca ggctacatgt ttgggaaagg gatctacttt gccgacatgg
2761 tgtccaaaag tgcaaactac tgccacacat ctcagggaga cccgattggc ttaatactgc
2821 tgggagaggt tgcccttgga aacatgtatg aactcaagca tgcttcacat atcagcaagt
2881 tacccaaggg caagcacagt gtcaaaggtt tgggaaaaac cacccctgac ccttcggcca
2941 gcatcaccct ggagggtgta gaggttccac tgggaacagg gatcccatct ggtgtcaacg
3001 acacctgcct gctgtataat gagtacattg tctacgacat tgctcaggtg aatctcaaat
3061 acctgctgaa actcaagttc aattttaaga catccctgtg gtaaagtgcg aggggtgggc
3121 tgtgcccagc acccagggcc tagggggcaa ttctccctag tgcctctgca ccagacacca
3181 caaaacctca gccatgctgc cgccgaaggg tggccccctc accgaatctc cttaggaagg
3241 gttttataca gacaggttaa agggctctgg tttcaagtcc cttgtccatg ctgcactggg
3301 gcaggccggt tgtttgtggt ttgtcctacc agccacagct ccatagacag cagctggcag
3361 tagagcaaaa gttggggaga ggattttgtt gtttgcctag actagtcctg agggaagaaa
3421 caccacgtca cagtcacgat gtctgcctta ctggcttccc cagggaagga aaaatgtgct
3481 tcctcccttt tttcaagggt tcatctttgc tttaattttg gcaaaatgtt aagcatttat
3541 tttgagctaa aaataaaagt taatttcata ctatatagat tttctttttt atcttgtatg
3601 tccccctctt agtctgctga gcttttgttt tgcttggttt tcagtgatag acatgggata
3661 gccaaaagaa gggactacct gaaaccccta actggggcga ctgagcctgt agtgtggtca
3721 gttcaaagtt gcatttggga ttctatgtct tccaaattga accgtctgta atcagtacag
3781 ccacccaaag ggctatagtt ctcaattaaa atgcaaatgg atatctaaaa aaaaaaaaaa
3841 aaaaa
//