LOCUS BC011750 1498 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens eukaryotic translation initiation factor 2B, subunit 2
beta, 39kDa, mRNA (cDNA clone MGC:19714 IMAGE:3534548), complete
cds.
ACCESSION BC011750
VERSION BC011750.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1498)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1498)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 19, 2003 this sequence version replaced BC011750.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 27 Row: d Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: Similarity but not
identity to protein.
FEATURES Location/Qualifiers
source 1..1498
/db_xref="H-InvDB:HIT000035423"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:19714 IMAGE:3534548"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1498
/gene="EIF2B2"
/gene_synonym="EIF-2Bbeta"
/gene_synonym="EIF2B"
/db_xref="GeneID:8892"
/db_xref="HGNC:HGNC:3258"
/db_xref="MIM:606454"
CDS 24..1079
/gene="EIF2B2"
/gene_synonym="EIF-2Bbeta"
/gene_synonym="EIF2B"
/codon_start=1
/product="eukaryotic translation initiation factor 2B,
subunit 2 beta, 39kDa"
/protein_id="AAH11750.1"
/db_xref="GeneID:8892"
/db_xref="HGNC:HGNC:3258"
/db_xref="MIM:606454"
/translation="MPGSAAKGSELSERIESFVETLKRGGGPRSSEEMARETLGLLRQ
IITDHRWSNAGELMELIRREGRRMTAAQPSETTVGNMVRRVLKIIREEYGRLHGRSDE
SDQQESLHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIH
SNEVIMTIGFSRTVEAFLKEAARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMT
DAAIFAVMSRVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSP
QFPNEEDSFHKFVAPEEVLPFTEGDILEKVSVHCPVFDYVPPELITLFISNIGGNAPS
YIYRLMSELYHPDDHVL"
BASE COUNT 395 a 366 c 389 g 348 t
ORIGIN
1 ggctgaaggc agctacctta aagatgccgg gatccgcagc gaagggctcg gagttgtcag
61 agaggatcga gagcttcgtg gagaccctga agcggggtgg tgggccgcgc agctccgagg
121 aaatggctcg ggagacccta gggttgctgc gccagatcat cacggaccac cgctggagca
181 acgcggggga gctgatggag ctgatccgca gagagggcag gaggatgacg gccgctcagc
241 cctccgagac caccgtgggc aacatggtgc ggagagtgct caagattatc cgggaggagt
301 atggcagact ccatggacgc agcgacgaga gtgatcagca ggagtccctg cacaaactgt
361 tgacatccgg aggcctaaac gaggatttca gcttccatta tgcccaactc cagtccaaca
421 tcattgaggc gattaatgag ctgctagtgg agctggaagg gacaatggag aacattgcag
481 cccaggctct ggagcacatt cactccaatg aggtgatcat gaccattggc ttctcccgaa
541 cagtagaggc cttcctcaaa gaggctgccc gaaagaggaa attccatgtc attgtagcag
601 agtgtgctcc tttctgccag ggtcatgaaa tggctgtgaa tttgtccaaa gcaggtattg
661 agacaactgt catgactgat gctgccattt ttgccgttat gtcaagagtc aacaaggtga
721 tcattggcac gaagaccatc ctggccaatg gggccctgag agctgtgaca ggaactcaca
781 ctctggcact ggcagcaaaa caccattcca ccccactcat cgtctgtgca cctatgttca
841 aactttctcc acagttcccc aatgaagaag actcatttca taagtttgtg gctcctgaag
901 aagtcctgcc attcacagaa ggggacattc tggagaaggt cagcgtgcat tgccctgtgt
961 ttgactacgt tcccccagag ctcattaccc tctttatctc caacattggt gggaatgcac
1021 cttcctacat ctaccgcctg atgagtgaac tctaccatcc tgatgatcat gttttatgac
1081 cgaccacacg tgtcctaagc agattgctta ggcagataca gaatgaagag gagacttgag
1141 tgttgctgct gaagcacatc cttgcaatgt gggagtgcac aggagtccac ctaaaaaaaa
1201 aatccttgat actgttgcct gcctttttag tcaccccgta acaagggcac acatccagga
1261 ctgtgtcttg cctttcagat cttaacagag cagcagggct taacttgttg attttggagc
1321 ctcttagtga cctggttgcg tctgtgtcag gaacttaaac tttctggttc agtagtgtgt
1381 taaacataac actgaatacc ttactgggat acagattttt gctcagaaat ggctatgaca
1441 ctttttctag gctctaccaa taaaagccac ttgaaggttc aaaaaaaaaa aaaaaaaa
//