LOCUS BC011606 2174 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens S-adenosylhomocysteine hydrolase, mRNA (cDNA clone
MGC:2319 IMAGE:3139231), complete cds.
ACCESSION BC011606
VERSION BC011606.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2174)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2174)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC011606.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 4 Row: o Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 9951914.
FEATURES Location/Qualifiers
source 1..2174
/db_xref="H-InvDB:HIT000035325"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2319 IMAGE:3139231"
/tissue_type="Placenta, choriocarcinoma"
/clone_lib="NIH_MGC_21"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2174
/gene="AHCY"
/gene_synonym="SAHH"
/db_xref="GeneID:191"
/db_xref="HGNC:HGNC:343"
/db_xref="MIM:180960"
CDS 75..1373
/gene="AHCY"
/gene_synonym="SAHH"
/codon_start=1
/product="S-adenosylhomocysteine hydrolase"
/protein_id="AAH11606.1"
/db_xref="GeneID:191"
/db_xref="HGNC:HGNC:343"
/db_xref="MIM:180960"
/translation="MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKP
LKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAW
KGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTG
VHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVV
AGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTT
GCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGR
RIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDE
AVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY"
BASE COUNT 522 a 580 c 604 g 468 t
ORIGIN
1 gctgcccgcc cagttcctgt tcccagactg aggcccagcc cccttcgccc gtttccatca
61 cgagtgccgc cagcatgtct gacaaactgc cctacaaagt cgccgacatc ggcctggctg
121 cctggggacg caaggccctg gacattgctg agaacgagat gccgggcctg atgcgtatgc
181 gggagcggta ctcggcctcc aagccactga agggcgcccg catcgctggc tgcctgcaca
241 tgaccgtgga gacggccgtc ctcattgaga ccctcgtcac cctgggtgct gaggtgcagt
301 ggtccagctg caacatcttc tccacccagg accatgcggc ggctgccatt gccaaggctg
361 gcattccggt gtatgcctgg aagggcgaaa cggacgagga gtacctgtgg tgcattgagc
421 agaccctgta cttcaaggac gggcccctca acatgattct ggacgacggg ggcgacctca
481 ccaacctcat ccacaccaag tacccgcagc ttctgccagg catccgaggc atctctgagg
541 agaccacgac tggggtccac aacctctaca agatgatggc caatgggatc ctcaaggtgc
601 ctgccatcaa tgtcaatgac tccgtcacca agagcaagtt tgacaacctc tatggctgcc
661 gggagtccct catagatggc atcaagcggg ccacagatgt gatgattgcc ggcaaggtag
721 cggtggtagc aggctatggt gatgtgggca agggctgtgc ccaggccctg cggggtttcg
781 gagcccgcgt catcatcacc gagattgacc ccatcaacgc actgcaggct gccatggagg
841 gctatgaggt gaccaccatg gatgaggcct gtcaggaggg caacatcttt gtcaccacca
901 caggctgtat tgacatcatc cttggccggc actttgagca gatgaaggat gatgccattg
961 tgtgtaacat tggacacttt gacgtggaga tcgatgtcaa gtggctcaac gagaacgccg
1021 tggagaaggt gaacatcaag ccgcaggtgg accggtatcg gttgaagaat gggcgccgca
1081 tcatcctgct ggccgagggt cggctggtca acctgggttg tgccatgggc caccccagct
1141 tcgtgatgag taactccttc accaaccagg tgatggcgca gatcgagctg tggacccatc
1201 cagacaagta ccccgttggg gttcatttcc tgcccaagaa gctggatgag gcagtggctg
1261 aagcccacct gggcaagctg aatgtgaagt tgaccaagct aactgagaag caagcccagt
1321 acctgggcat gtcctgtgat ggccccttca agccggatca ctaccgctac tgagagccag
1381 gtctgcgttt caccctccag ctgctgtcct tgcccaggcc ccacctctcc tccctaagag
1441 ctaatggcac caactttgtg attggtttgt cagtgtcccc catcgactct ctggggctga
1501 tcacttagtt tttggcctct gctgcagccg tcatactgtt ccaaatgtgg cagcgggaac
1561 agagtaccct cttcaagccc cggtcatgat ggaggtccca gccacaggga accatgagct
1621 cagtggtctt ggaacagctc actaagtcag tccttcctta gcctggaagt cagtagtgga
1681 gtcacaaagc ccatgtgttt tgccatctag gccttcacct ggtctgtgga cttatacctg
1741 tgtgcttggt ttacaggtcc agtggttctt cagcccatga cagatgagaa ggggctatat
1801 tgaagggcaa agaggaactg ttgtttgaat tttcctgaga gcctggctta gtgctgggcc
1861 ttctcttaaa cctcattaca atgaggttag tacttttagt ccctgtttta caggggttag
1921 aatagactgt taaggggcaa ctgagaaaga acagagaagt gacagctagg ggttgagagg
1981 ggccagaaaa acatgaatgc aggcagattt cgtgaaatct gccaccactt tataaccaga
2041 tggttccttt ctcaaccctg ggtcaaaaag agaataattt ggcctataat gttaaaagaa
2101 agcaggaagg tgggtaaata aaaatcttgg tgcctggaaa aaaaaaaaaa aaaaaaaaaa
2161 aaaaaaaaaa aaaa
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