LOCUS BC011558 2439 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens nuclear factor (erythroid-derived 2)-like 2, mRNA
(cDNA clone MGC:20033 IMAGE:4548874), complete cds.
ACCESSION BC011558
VERSION BC011558.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2439)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2439)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP/Gazdar
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 29 Row: a Column: 18
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 20149575.
FEATURES Location/Qualifiers
source 1..2439
/db_xref="H-InvDB:HIT000035288"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:20033 IMAGE:4548874"
/tissue_type="Lung, large cell carcinoma"
/clone_lib="NIH_MGC_18"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2439
/gene="NFE2L2"
/gene_synonym="NRF2"
/db_xref="GeneID:4780"
/db_xref="HGNC:HGNC:7782"
/db_xref="MIM:600492"
CDS 114..1931
/gene="NFE2L2"
/gene_synonym="NRF2"
/codon_start=1
/product="nuclear factor (erythroid-derived 2)-like 2"
/protein_id="AAH11558.1"
/db_xref="GeneID:4780"
/db_xref="HGNC:HGNC:7782"
/db_xref="MIM:600492"
/translation="MMDLELPPPGLPSQQDMDLIDILWRQDIDLGVSREVFDFSQRRK
EYELEKQKKLEKERQEQLQKEQEKAFFAQLQLDEETGEFLPIQPAQHIQSETSGSANY
SQVAHIPKSDALYFDDCMQLLAQTFPFVDDNEVSSATFQSLVPDIPGHIESPVFIATN
QAQSPETSVAQVAPVDLDGMQQDIEQVWEELLSIPELQCLNIENDKLVETTMVPSPEA
KLTEVDNYHFYSSIPSMEKEVGNCSPHFLNAFEDSFSSILSTEDPNQLTVNSLNSDAT
VNTDFGDEFYSAFIAEPSISNSMPSPATLSHSLSELLNGPIDVSDLSLCKAFNQNHPE
STAEFNDSDSGISLNTSPSVASPEHSVESSSYGDTLLGLSDSEVEELDSAPGSVKQNG
PKTPVHSSGDMVQPLSPSQGQSTHVHDAQCENTPEKELPVSPGHRKTPFTKDKHSSRL
EAHLTRDELRAKALHIPFPVEKIINLPVVDFNEMMSKEQFNEAQLALIRDIRRRGKNK
VAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGENDKSLHLLKKQLSTLYLEVFS
MLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDVKKN"
BASE COUNT 804 a 527 c 475 g 633 t
ORIGIN
1 gcagccgcca ccgccgccgc cgccgccacc agagccgccc tgtccgcgcc gcgcctcggc
61 agccggaaca gggccgccgt cggggagccc caacacacgg tccacagctc atcatgatgg
121 acttggagct gccgccgccg ggactcccgt cccagcagga catggatttg attgacatac
181 tttggaggca agatatagat cttggagtaa gtcgagaagt atttgacttc agtcagcgac
241 ggaaagagta tgagctggaa aaacagaaaa aacttgaaaa ggaaagacaa gaacaactcc
301 aaaaggagca agagaaagcc tttttcgctc agttacaact agatgaagag acaggtgaat
361 ttctcccaat tcagccagcc cagcacatcc agtcagaaac cagtggatct gccaactact
421 cccaggttgc ccacattccc aaatcagatg ctttgtactt tgatgactgc atgcagcttt
481 tggcgcagac attcccgttt gtagatgaca atgaggtttc ttcggctacg tttcagtcac
541 ttgttcctga tattcccggt cacatcgaga gcccagtctt cattgctact aatcaggctc
601 agtcacctga aacttctgtt gctcaggtag cccctgttga tttagacggt atgcaacagg
661 acattgagca agtttgggag gagctattat ccattcctga gttacagtgt cttaatattg
721 aaaatgacaa gctggttgag actaccatgg ttccaagtcc agaagccaaa ctgacagaag
781 ttgacaatta tcatttttac tcatctatac cctcaatgga aaaagaagta ggtaactgta
841 gtccacattt tcttaatgct tttgaggatt ccttcagcag catcctctcc acagaagacc
901 ccaaccagtt gacagtgaac tcattaaatt cagatgccac agtcaacaca gattttggtg
961 atgaatttta ttctgctttc atagctgagc ccagtatcag caacagcatg ccctcacctg
1021 ctactttaag ccattcactc tctgaacttc taaatgggcc cattgatgtt tctgatctat
1081 cactttgcaa agctttcaac caaaaccacc ctgaaagcac agcagaattc aatgattctg
1141 actccggcat ttcactaaac acaagtccca gtgtggcatc accagaacac tcagtggaat
1201 cttccagcta tggagacaca ctacttggcc tcagtgattc tgaagtggaa gagctagata
1261 gtgcccctgg aagtgtcaaa cagaatggtc ctaaaacacc agtacattct tctggggata
1321 tggtacaacc cttgtcacca tctcaggggc agagcactca cgtgcatgat gcccaatgtg
1381 agaacacacc agagaaagaa ttgcctgtaa gtcctggtca tcggaaaacc ccattcacaa
1441 aagacaaaca ttcaagccgc ttggaggctc atctcacaag agatgaactt agggcaaaag
1501 ctctccatat cccattccct gtagaaaaaa tcattaacct ccctgttgtt gacttcaacg
1561 aaatgatgtc caaagagcag ttcaatgaag ctcaacttgc attaattcgg gatatacgta
1621 ggaggggtaa gaataaagtg gctgctcaga attgcagaaa aagaaaactg gaaaatatag
1681 tagaactaga gcaagattta gatcatttga aagatgaaaa agaaaaattg ctcaaagaaa
1741 aaggagaaaa tgacaaaagc cttcacctac tgaaaaaaca actcagcacc ttatatctcg
1801 aagttttcag catgctacgt gatgaagatg gaaaacctta ttctcctagt gaatactccc
1861 tgcagcaaac aagagatggc aatgttttcc ttgttcccaa aagtaagaag ccagatgtta
1921 agaaaaacta gatttaggag gatttgacct tttctgagct agtttttttg tactattata
1981 ctaaaagctc ctactgtgat gtgaaatgct catactttat aagtaattct atgcaaaatc
2041 atagccaaaa ctagtataga aaataatacg aaactttaaa aagcattgga gtgtcagtat
2101 gttgaatcag tagtttcact ttaactgtaa acaatttctt aggacaccat ttgggctagt
2161 ttctgtgtaa gtgtaaatac tacaaaaact tatttatact gttcttatgt catttgttat
2221 attcatagat ttatatgatg atatgacatc tggctaaaaa gaaattattg caaaactaac
2281 cactatgtac ttttttataa atactgtatg gacaaaaaat ggcatttttt atattaaatt
2341 gtttagctct ggcaaaaaaa aaaaatttta agagctggta ctaataaagg attattatga
2401 ctgttaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
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