LOCUS BC010574 3445 bp mRNA linear HUM 11-AUG-2006
DEFINITION Homo sapiens glutamate receptor, ionotropic, AMPA 2, mRNA (cDNA
clone MGC:17079 IMAGE:4215347), complete cds.
ACCESSION BC010574
VERSION BC010574.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3445)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3445)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: o Column: 9
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4758479.
FEATURES Location/Qualifiers
source 1..3445
/db_xref="H-InvDB:HIT000035004"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17079 IMAGE:4215347"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3445
/gene="GRIA2"
/gene_synonym="GLURB"
/gene_synonym="HBGR2"
/db_xref="GeneID:2891"
/db_xref="HGNC:HGNC:4572"
/db_xref="MIM:138247"
CDS 280..2931
/gene="GRIA2"
/gene_synonym="GLURB"
/gene_synonym="HBGR2"
/codon_start=1
/product="GRIA2 protein"
/protein_id="AAH10574.1"
/db_xref="GeneID:2891"
/db_xref="HGNC:HGNC:4572"
/db_xref="MIM:138247"
/translation="MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAF
RVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITS
FCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLVEYYQWDKFAYLYDSDRGLST
LQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVND
IVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIER
WSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANP
AVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEV
DKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLA
AEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREE
VIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSR
FSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMRRGCDISPRSLSGRIVGG
VWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTLDSGSTKEFFRR
SKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQRKPCD
TMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGG
GDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKVAKNAQNIN
PSSSQNSQNFATYKEGYNVYGIESVKI"
BASE COUNT 1010 a 668 c 847 g 920 t
ORIGIN
1 ccgagacact gggaccacag cggcagctcc gctgaaaact gcattcagcc agtcctccgg
61 acttctggag cggggacagg gcgcagggca tcagcagcca ccagcaggac ctgggaaata
121 gggattcttc tgcctccact tcaggtttta gcagcttggt gctaaattgc tgtctcaaaa
181 tgcagaggat ctaatttgca gaggaaaaca gccaaagaag gaagaggagg aaaaggaaaa
241 aaaaaggggt atattgtgga tgctctactt ttcttggaaa tgcaaaagat tatgcatatt
301 tctgtcctcc tttctcctgt tttatgggga ctgatttttg gtgtctcttc taacagcata
361 cagatagggg ggctatttcc taggggcgcc gatcaagaat acagtgcatt tcgagtaggg
421 atggttcagt tttccacttc ggagttcaga ctgacacccc acatcgacaa tttggaggtg
481 gcaaacagct tcgcagtcac taatgctttc tgctcccagt tttcgagagg agtctatgct
541 atttttggat tttatgacaa gaagtctgta aataccatca catcattttg cggaacactc
601 cacgtctcct tcatcactcc cagcttccca acagatggca cacatccatt tgtcattcag
661 atgagacccg acctcaaagg agctctcctt agcttagttg aatactatca atgggacaag
721 tttgcatacc tctatgacag tgacagaggc ttatcaacac tgcaagctgt gctggattct
781 gctgctgaaa agaaatggca agtgactgct atcaatgtgg gaaacattaa caatgacaag
841 aaagatgaga tgtaccgatc actttttcaa gatctggagt taaaaaagga acggcgtgta
901 attctggact gtgaaaggga taaagtaaac gacattgtag accaggttat taccattgga
961 aaacatgtta aagggtacca ctacatcatt gcaaatctgg gatttactga tggagaccta
1021 ttaaaaatcc agtttggagg tgcaaatgtc tctggatttc agatagtgga ctatgatgat
1081 tcgttggtat ctaaatttat agaaagatgg tcaacactgg aagaaaaaga ataccctgga
1141 gctcacacaa caacaattaa gtatacttct gctctgacct atgatgccgt tcaagtgatg
1201 actgaagcct tccgcaacct aaggaagcaa agaattgaaa tctcccgaag ggggaatgca
1261 ggagactgtc tggcaaaccc agcagtgccc tggggacaag gtgtagaaat agaaagggcc
1321 ctcaaacagg ttcaggttga aggtctctca ggaaatataa agtttgacca gaatggaaaa
1381 agaataaact atacaattaa catcatggag ctcaaaacta atgggccccg gaagattggc
1441 tactggagtg aagtggacaa aatggttgtt acccttactg agctcccttc tggaaatgac
1501 acctctgggc ttgagaataa gactgttgtt gtcaccacaa ttttggaatc tccgtatgtt
1561 atgatgaaga aaaatcatga aatgcttgaa ggcaatgagc gctatgaggg ctactgtgtt
1621 gacctggctg cagaaatcgc caaacattgt gggttcaagt acaagttgac aattgttggt
1681 gatggcaagt atggggccag ggatgcagac acgaaaattt ggaatgggat ggttggagaa
1741 cttgtatatg ggaaagctga tattgcaatt gctccattaa ctattaccct tgtgagagaa
1801 gaggtgattg acttctcaaa gcccttcatg agcctcggga tatctatcat gatcaagaag
1861 cctcagaagt ccaaaccagg agtgttttcc tttcttgatc ctttagccta tgagatctgg
1921 atgtgcattg tttttgccta cattggggtc agtgtagttt tattcctggt cagcagattt
1981 agcccctacg agtggcacac tgaggagttt gaagatggaa gagaaacaca aagtagtgaa
2041 tcaactaatg aatttgggat ttttaatagt ctctggtttt ccttgggtgc ctttatgcgg
2101 cgaggatgcg atatttcgcc aagatccctc tctgggcgca ttgttggagg tgtgtggtgg
2161 ttctttaccc tgatcataat ctcctcctac acggctaact tagctgcctt cctgactgta
2221 gagaggatgg tgtctcccat cgaaagtgct gaggatcttt ctaagcaaac agaaattgct
2281 tatggaacat tagactctgg ctccactaaa gagtttttca ggagatctaa aattgcagtg
2341 tttgataaaa tgtggaccta catgcggagt gcggagccct ctgtgtttgt gaggactacg
2401 gccgaagggg tggctagagt gcggaagtcc aaagggaaat atgcctactt gttggagtcc
2461 acgatgaacg agtacattga gcaaaggaag ccttgcgaca ccatgaaagt tggtggaaac
2521 ctggattcca aaggctatgg catcgcaaca cctaaaggat cctcattaag aaatgcggtt
2581 aacctcgcag tactaaaact gaatgaacaa ggcctgttgg acaaattgaa aaacaaatgg
2641 tggtacgaca aaggagagtg cggcagcggg ggaggtgatt ccaaggaaaa gaccagtgcc
2701 ctcagtctga gcaacgttgc tggagtattc tacatccttg tcgggggcct tggtttggca
2761 atgctggtgg ctttgattga gttctgttac aagtcaaggg ccgaggcgaa acgaatgaag
2821 gtggcaaaga atgcacagaa tattaaccct tcttcctcgc agaattcaca gaattttgca
2881 acttataagg aaggttacaa cgtatatggc atcgaaagtg ttaaaattta ggggatgacc
2941 ttgaatgatg ccatgaggaa caaggcaagg ctgtcaatta caggaagtac tggagaaaat
3001 ggacgtgtta tgactccaga atttcccaaa gcagtgcatg ctgtccctta cgtgagtcct
3061 ggcatgggaa tgaatgtcag tgtgactgat ctctcgtgat tgataagaac cttttgagtg
3121 ccttacacaa tggttttctt gtgtgtttat tgtcaaagtg gtgagaggca tccagtatct
3181 tgaagacttt tctttcagcc aagaattctt aaatatgtgg agttcatctt gaattgtaag
3241 gaatgattaa ttaaaacaca acatcttttt ctactcgagt tacagacaaa gcgtggtgga
3301 catgcacagc taacatggaa gtactataat ttacctgaag tctttgtaca gacaacaaac
3361 ctgtttctgc agccactatt gttagtctct tgattcataa tgacttaagc acacttgaca
3421 tcaactgcat caagatgtga catgt
//