LOCUS BC010451 3072 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens CDC42 effector protein (Rho GTPase binding) 4, mRNA
(cDNA clone MGC:17125 IMAGE:4181539), complete cds.
ACCESSION BC010451
VERSION BC010451.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3072)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3072)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: k Column: 16
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 48375181.
FEATURES Location/Qualifiers
source 1..3072
/db_xref="H-InvDB:HIT000034952"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17125 IMAGE:4181539"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..3072
/gene="CDC42EP4"
/gene_synonym="BORG4"
/gene_synonym="CEP4"
/gene_synonym="KAIA1777"
/gene_synonym="MGC17125"
/gene_synonym="MGC3740"
/db_xref="GeneID:23580"
/db_xref="HGNC:HGNC:17147"
/db_xref="MIM:605468"
CDS 201..1271
/gene="CDC42EP4"
/gene_synonym="BORG4"
/gene_synonym="CEP4"
/gene_synonym="KAIA1777"
/gene_synonym="MGC17125"
/gene_synonym="MGC3740"
/codon_start=1
/product="CDC42 effector protein (Rho GTPase binding) 4"
/protein_id="AAH10451.1"
/db_xref="GeneID:23580"
/db_xref="HGNC:HGNC:17147"
/db_xref="MIM:605468"
/translation="MLILKQLVSSSVHSKRRSRADLTAEMISAPLGDFRHTMHVGRAG
DAFGDTSFLNSKAGEPDGESLDEQPSSSSSKRSLLSRKFRGSKRSQSVTRGEREQRDM
LGSLRDSALFVKNAMSLPQLNEKEAAEKGTSKLPKSLSSSPVKKANDGEGGDEEAGTE
EAVPRRNGAAGPHSPDPLLDEQAFGDLTDLPVVPKATYGLKHAESIMSFHIDLGPSML
GDVLSIMDKEEWDPEEGEGGYHGDEGAAGTITQAPPYAVAAPPLARQEGKAGPDLPSL
PSHALEDEGWAAAAPSPGSARSMGSHTTRDSSSLSSCTSGILEERSPAFRGPDRARAA
VSRQPDKEFSFMDEEEEDEIRV"
BASE COUNT 632 a 921 c 868 g 651 t
ORIGIN
1 ctgacagggg ccgccagccc ctccgccgcg cggagcccac gaaggggaca gcgcagccgg
61 cccagagctc gggtctccgg ggaccgagcc ttatgatctc ctcattgcgt ccccctctgc
121 ccactggact tggacttcag atctgacccc agacctgccg gctacctcgg gagggcccac
181 ctccccgccc atccagcaag atgctaatcc tcaagcaact ggtgtccagc tcggtgcact
241 ccaagcgccg ttcccgagcg gacctcacgg ccgagatgat cagcgccccg ctgggcgact
301 tccgccacac catgcacgtt ggccgggccg gagacgcctt tggggacacc tccttcctca
361 atagcaaggc tggcgagccc gacggcgagt ccttggacga acagccctct tcttcatctt
421 ccaaacgcag tctcctgtcc aggaagttcc ggggcagcaa gcggtcacag tcggtgacca
481 ggggggagcg ggagcagcgt gacatgctgg gctccctgcg ggactcggcc ctgtttgtca
541 agaatgccat gtccctgccc cagctcaatg agaaggaggc cgcggagaag ggcaccagta
601 agctgcccaa gagcctgtca tccagccccg tgaagaaggc caatgacggg gagggcggcg
661 atgaggaggc gggcacggag gaggcagtgc cccgtcggaa tggggccgcg ggtccacatt
721 cccctgaccc cctcctcgat gagcaggcct ttggggatct gacagatctg cctgtcgtgc
781 ccaaggccac gtacgggctg aagcatgcgg agtccatcat gtccttccac atcgacctgg
841 ggccctccat gctgggtgac gtcctcagca tcatggacaa ggaggagtgg gaccccgagg
901 agggggaggg tggttaccat ggcgatgagg gcgccgctgg caccatcacc caggctcccc
961 cgtacgccgt ggcggcccct cccctggcaa ggcaggaagg caaggctggc ccagacttgc
1021 cctccctccc ctcccatgct ctggaggatg aggggtgggc agcagcggcc cccagccccg
1081 gctcagcccg cagcatgggc agccacacca cacgggacag cagctccctc tccagctgca
1141 cctcaggcat cctggaggag cgcagccctg ccttccgggg gccggacagg gcccgggctg
1201 ctgtctcaag acagccagac aaggagttct ccttcatgga tgaggaggag gaggatgaaa
1261 tccgtgtgtg aggcggacag tgggtggcca ccgggagctc ttggctgcat cttctccctg
1321 cccccacccc actatgacct ttgaccctac ggcgcagggg cagccaggac ccttgattca
1381 gaccatggac cctggacctt gtagatgagg gacactggcc tggccctcgg gtcttcggag
1441 gacgtagggg gctggcatgg gtgccgactg gctgcctgac ttcatcatgc tccctgcact
1501 taggctgcgt gggacaaggg ctgtgttgtc acagcaggaa taggttttcc tctgttggcc
1561 tccctttcct ccaccctggc ctcaaatgga tgccagatgc caaccccagt tctggccacg
1621 tacagccagc gggtcagccc agaggcagcc tcagctccag ggctaaggac tctcggctcc
1681 cattttctct gctggcgttt ctgctgtgcc cagcagtggc tgctggggaa gcagctgcag
1741 caggagggag acggtcttgc ctctcagccc ctccctgccc caccccagct cctgccctgg
1801 aaatctggag ccccttggag ctgagctgga cggggggcca gctgcgagca tgtgcactaa
1861 acgcagccct ttccagggga agagaacagg atggagaatg gaaggaaagc cccccaggct
1921 tcgtgaattg caagaaggga cccttccagg atgacactag gaacagggct agggcactcg
1981 ctcagtccct aggggcttgt ttgttcttta ttattgtgtt taaatcctta tagagcaata
2041 tcaggatggt gttaataggt ctgcctcaga atgagaatca atccttttag aaaaccttta
2101 tactaagcct cctcttcaaa attcacagtg gcgattagcg gactggagtc tggtggcgat
2161 tagcggactg gagtctgggg acatccgtgg caaagacacc agctcaactt tagtgcttcc
2221 caactttatt tagaatgaca tggggtgggt gtctggtgtg tgtgttttcc ctacgcacct
2281 cccatagcta ttaacaactg aggaaggcca gtgcagaata tttttggaga acgatttttt
2341 ttttaaataa tatatcattc ctatgggggg aaagcctttt ttttcttttt ggctgagtta
2401 ttccctccct cccctcaata ccctcagtac tgactacttc cctttctttt ctcaggcctc
2461 cccccaccga cttttgaggc cagggttggc cagatttagc aaaaccaaaa cagagtgctg
2521 agttaaacgc aaatttcagg taaacaaaag ataattttct agcattaata tgccccacgc
2581 aatatttgga acacttatgt gaaaaatgat ttgtttttct gaaattcacg tttctctctg
2641 agtcctgtaa ctgtccccga ggggattgag cagaagctcg ggtatgagcc ctgaggttga
2701 ctgccggtta tttttctgtc ctgggaacag cctgacccac ctccctgtct ccatgtagcc
2761 agtgagggga gggggagaca cagaaccaac cacagccagg ggcgtcccca tggtgactgt
2821 ggcccggccc ctcctctctt gcctgactct cctctcttgc ctgactctag acactaactt
2881 agttccaggt tcggtgccct gttggtgctc ctgtttccaa tagcttaggt cccatggtgg
2941 gggaggaacc tcaggggcta tgcagccccc gccagctgcc ctcgaatccc gtccaggcca
3001 attccagatt ctaaactgat ttttttcatg atattgtcaa aacagtgagg aaacattaaa
3061 aaaaaaaaaa aa
//