LOCUS BC010423 2680 bp mRNA linear HUM 24-FEB-2004
DEFINITION Homo sapiens poliovirus receptor-related 4, mRNA (cDNA clone
MGC:15117 IMAGE:3610849), complete cds.
ACCESSION BC010423
VERSION BC010423.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2680)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2680)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (10-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steve Jones, Sarah Barber, Mabel Brown-John, Yaron Butterfield,
Andy Chan, Steve S. Chand, William Chow, Alison Cloutier, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Amara Masson, Mike R. Mayo, Josh Moran, Ryan Morin,
Teika Olson, Diana Palmquist, Anca Petrescu, Anna Liisa Prahbu,
Parvaneh Saeedi, JR Santos, Angelique Schnerch, Ursula Skalska,
Duane Smailus, Jeff Stott, Miranda Tsai, George Yang, Jacquie
Schein, Asim Siddiqui, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 23 Row: p Column: 22
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 16716338.
FEATURES Location/Qualifiers
source 1..2680
/db_xref="H-InvDB:HIT000034932"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15117 IMAGE:3610849"
/tissue_type="Pancreas, adenocarcinoma"
/clone_lib="NIH_MGC_39"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2680
/gene="PVRL4"
/gene_synonym="LNIR"
/gene_synonym="nectin-4"
/gene_synonym="PRR4"
/db_xref="GeneID:81607"
CDS 248..1780
/gene="PVRL4"
/gene_synonym="LNIR"
/gene_synonym="nectin-4"
/gene_synonym="PRR4"
/codon_start=1
/product="PVRL4 protein"
/protein_id="AAH10423.1"
/db_xref="GeneID:81607"
/translation="MPLSLGAEMWGPEAWLLLLLLLASFTGRCPAGELETSDVVTVVL
GQDAKLPCFYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPP
PPRNPLDGSVLLRNAVQADEGEYECRVSTFPAGSFQARLRLRVLVPPLPSLNPGPALE
EGQGLTLAASCTAEGSPAPSVTWDTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNG
QPLTCVVSHPGLLQDQRITHILHVSFLAEASVRGLEDQNLWHIGREGAMLKCLSEGQP
PPSYNWTRLDGPLPSGVRVDGDTLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLD
PQEDSGKQVDLVSASVVVVGVIAALLFCLLVVVVVLMSRYHRRKAQQMTQKYEEELTL
TRENSIRRLHSHHTDPRSQPEESVGLRAEGHPDSLKDNSSCSVMSEEPEGRSYSTLTT
VREIETQTELLSPGSGRAEEEEDQDEGIKQAMNHFVQENGTLRAKPTGNGIYINGRGH
LV"
misc_feature 365..661
/gene="PVRL4"
/gene_synonym="LNIR"
/gene_synonym="nectin-4"
/gene_synonym="PRR4"
/note="IGv; Region: Immunoglobulin domain variable region
(v) subfamily"
/db_xref="CDD:cd00099"
misc_feature 1013..1237
/gene="PVRL4"
/gene_synonym="LNIR"
/gene_synonym="nectin-4"
/gene_synonym="PRR4"
/note="IGcam; Region: Immunoglobulin domain cell adhesion
molecule (cam) subfamily"
/db_xref="CDD:cd00931"
BASE COUNT 533 a 734 c 815 g 598 t
ORIGIN
1 cacagcgtgg gaagcagctc tgggggagct cggagctccc gatcacggct tcttgggggt
61 agctacggct gggtgtgtag aacggggccg gggctggggc tgggtcccct agtggagacc
121 caagtgcgag aggcaagaac tctgcagctt cctgccttct gggtcagttc cttattcaag
181 tctgcagccg gctcccaggg agatctcggt ggaacttcag aaacgctggg cagtctgcct
241 ttcaaccatg cccctgtccc tgggagccga gatgtggggg cctgaggcct ggctgctgct
301 gctgctactg ctggcatcat ttacaggccg gtgccccgcg ggtgagctgg agacctcaga
361 cgtggtaact gtggtgctgg gccaggacgc aaaactgccc tgcttctacc gaggggactc
421 cggcgagcaa gtggggcaag tggcatgggc tcgggtggac gcgggcgaag gcgcccagga
481 actagcgcta ctgcactcca aatacgggct tcatgtgagc ccggcttacg agggccgcgt
541 ggagcagccg ccgcccccac gcaaccccct ggacggctca gtgctcctgc gcaacgcagt
601 gcaggcggat gagggcgagt acgagtgccg ggtcagcacc ttccccgccg gcagcttcca
661 ggcgcggctg cggctccgag tgctggtgcc tcccctgccc tcactgaatc ctggtccagc
721 actagaagag ggccagggcc tgaccctggc agcctcctgc acagctgagg gcagcccagc
781 ccccagcgtg acctgggaca cggaggtcaa aggcacaacg tccagccgtt ccttcaagca
841 ctcccgctct gctgccgtca cctcagagtt ccacttggtg cctagccgca gcatgaatgg
901 gcagccactg acttgtgtgg tgtcccatcc tggcctgctc caggaccaaa ggatcaccca
961 catcctccac gtgtccttcc ttgctgaggc ctctgtgagg ggccttgaag accaaaatct
1021 gtggcacatt ggcagagaag gagctatgct caagtgcctg agtgaagggc agccccctcc
1081 ctcatacaac tggacacggc tggatgggcc tctgcccagt ggggtacgag tggatgggga
1141 cactttgggc tttcccccac tgaccactga gcacagcggc atctacgtct gccatgtcag
1201 caatgagttc tcctcaaggg attctcaggt cactgtggat gttcttgacc cccaggaaga
1261 ctctgggaag caggtggacc tagtgtcagc ctcggtggtg gtggtgggtg tgatcgccgc
1321 actcttgttc tgccttctgg tggtggtggt ggtgctcatg tcccgatacc atcggcgcaa
1381 ggcccagcag atgacccaga aatatgagga ggagctgacc ctgaccaggg agaactccat
1441 ccggaggctg cattcccatc acacggaccc caggagccag ccggaggaga gtgtagggct
1501 gagagccgag ggccaccctg atagtctcaa ggacaacagt agctgctctg tgatgagtga
1561 agagcccgag ggccgcagtt actccacgct gaccacggtg agggagatag aaacacagac
1621 tgaactgctg tctccaggct ctgggcgggc cgaggaggag gaagatcagg atgaaggcat
1681 caaacaggcc atgaaccatt ttgttcagga gaatgggacc ctacgggcca agcccacggg
1741 caatggcatc tacatcaatg ggcggggaca cctggtctga cccaggcctg cctcccttcc
1801 ctaggcctgg ctccttctgt tgacatggga gattttagct catcttgggg gcctccttaa
1861 acacccccat ttcttgcgga agatgctccc catcccactg actgcttgac ctttacctcc
1921 aacccttctg ttcatcggga gggctccacc aattgagtct ctcccaccat gcatgcaggt
1981 cactgtgtgt gtgcatgtgt gcctgtgtga gtgttgactg actgtgtgtg tgtggagggg
2041 tgactgtccg tggaggggtg actgtgtccg tggtgtgtat tatgctgtca tatcagagtc
2101 aagtgaactg tggtgtatgt gccacgggat ttgagtggtt gcgtgggcaa cactgtcagg
2161 gtttggcgtg tgtgtcatgt ggctgtgtgt gacctctgcc tgaaaaagca ggtattttct
2221 cagaccccag agcagtatta atgatgcaga ggttggagga gagaggtgga gactgtggct
2281 cagacccagg tgtgcgggca tagctggagc tggaatctgc ctccggtgtg agggaacctg
2341 tctcctacca cttcggagcc atgggggcaa gtgtgaagca gccagtccct gggtcagcca
2401 gaggcttgaa ctgttacaga agccctctgc cctctggtgg cctctgggcc tgctgcatgt
2461 acatattttc tgtaaatata catgcgccgg gagcttcttg caggaatact gctccgaatc
2521 acttttaatt tttttctttt ttttttcttg ccctttccat tagttgtatt ttttatttat
2581 ttttattttt attttttttt agagtttgag tccagcctgg acgatatagc cagaccctgt
2641 ctgtaaaaaa accaaaaccc aaaaaaaaaa aaaaaaaaaa
//