LOCUS BC010240 2029 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cathepsin B, mRNA (cDNA clone MGC:17266
IMAGE:4154307), complete cds.
ACCESSION BC010240
VERSION BC010240.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2029)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2029)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (05-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 19 Row: f Column: 16.
FEATURES Location/Qualifiers
source 1..2029
/db_xref="H-InvDB:HIT000034868"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17266 IMAGE:4154307"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2029
/gene="CTSB"
/gene_synonym="APPS"
/gene_synonym="CPSB"
/db_xref="GeneID:1508"
/db_xref="HGNC:HGNC:2527"
/db_xref="MIM:116810"
CDS 193..1212
/gene="CTSB"
/gene_synonym="APPS"
/gene_synonym="CPSB"
/codon_start=1
/product="cathepsin B"
/protein_id="AAH10240.1"
/db_xref="GeneID:1508"
/db_xref="HGNC:HGNC:2527"
/db_xref="MIM:116810"
/translation="MWQLWASLCCLLVLANARSRPSFHPVSDELVNYVNKRNTTWQAG
HNFYNVDMGYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQ
GSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWN
FWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPT
YKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMG
GHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQ
YWEKI"
BASE COUNT 483 a 558 c 549 g 439 t
ORIGIN
1 ggctccggca accgctccgg caacgccaac cgctccgctg cgcgcaggct gggctgcagg
61 ctctcggctg cagcgctggg ctggtgtgca gtggtgcgac cacggctcac ggcagcctca
121 gccacccaga tgtaagcgat ctggttccca cctcagcctc ccgagtagtg gatctaggat
181 ccggcttcca acatgtggca gctctgggcc tccctctgct gcctgctggt gttggccaat
241 gcccggagca ggccctcttt ccatcccgtg tcggatgagc tggtcaacta tgtcaacaaa
301 cggaatacca cgtggcaggc cgggcacaac ttctacaacg tggacatggg ctacttgaag
361 aggctatgtg gtaccttcct gggtgggccc aagccacccc agagagttat gtttaccgag
421 gacctgaagc tgcctgcaag cttcgatgca cgggaacaat ggccacagtg tcccaccatc
481 aaagagatca gagaccaggg ctcctgtggc tcctgctggg ccttcggggc tgtggaagcc
541 atctctgacc ggatctgcat ccacaccaat gcgcacgtca gcgtggaggt gtcggcggag
601 gacctgctca cctgctgtgg cagcatgtgt ggggacggct gtaatggtgg ctatcctgct
661 gaagcttgga acttctggac aagaaaaggc ctggtttctg gtggcctcta tgaatcccat
721 gtagggtgca gaccgtactc catccctccc tgtgagcacc acgtcaacgg ctcccggccc
781 ccatgcacgg gggagggaga tacccccaag tgtagcaaga tctgtgagcc tggctacagc
841 ccgacctaca aacaggacaa gcactacgga tacaattcct acagcgtctc caatagcgag
901 aaggacatca tggccgagat ctacaaaaac ggccccgtgg agggagcttt ctctgtgtat
961 tcggacttcc tgctctacaa gtcaggagtg taccaacacg tcaccggaga gatgatgggt
1021 ggccatgcca tccgcatcct gggctgggga gtggagaatg gcacacccta ctggctggtt
1081 gccaactcct ggaacactga ctggggtgac aatggcttct ttaaaatact cagaggacag
1141 gatcactgtg gaatcgaatc agaagtggtg gctggaattc cacgcaccga tcagtactgg
1201 gaaaagatct aatctgccgt gggcctgtcg tgccagtcct gggggcgaga tcggggtaga
1261 aatgcatttt attctttaag ttcacgtaag atacaagttt cagacagggt ctgaaggact
1321 ggattggcca aacatcagac ctgtcttcca aggagaccaa gtcctggcta catcccagcc
1381 tgtggttaca gtgcagacag gccatgtgag ccaccgctgc cagcacagag cgtccttccc
1441 cctgtagact agtgccgtag ggagtacctg ctgccccagc tgactgtggc cccctccgtg
1501 atccatccat ctccagggag caagacagag acgcaggaat ggaaagcgga gttcctaaca
1561 ggatgaaact tcccccatca gttcccccag tacctccaag caagtagctt tccacatttg
1621 tcacagaaat cagaggagag atggtgttgg gagccctttg gagaacgcca gtctcccagg
1681 ccccctgcat ctatcgagtt tgcaatgtca caacctctct gatcttgtgc tcagcatgat
1741 tctttaatag aagttttatt ttttcgtgca ctctgctaat catgtgggtg agccagtgga
1801 acagcgggag acctgtgcta gttttacaga ttgcctccta atgacgcggc tcaaaaggaa
1861 accaagtggt caggagttgt ttctgaccca ctgatctcta ctaccacaag gaaaatagtt
1921 taggagaaac cagcttttac tgtttttgaa aaattacagc ttcaccctgt caagttaaca
1981 aggaatgcct gtgccaataa aaggtttctc caaaaaaaaa aaaaaaaaa
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