LOCUS BC010061 1700 bp mRNA linear HUM 06-JUN-2006
DEFINITION Homo sapiens Meckel syndrome, type 1, mRNA (cDNA clone MGC:19519
IMAGE:3952532), complete cds.
ACCESSION BC010061
VERSION BC010061.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1700)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1700)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC010061.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 27 Row: k Column: 11
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 8923323.
FEATURES Location/Qualifiers
source 1..1700
/db_xref="H-InvDB:HIT000034773"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:19519 IMAGE:3952532"
/tissue_type="Ovary, adenocarcinoma"
/clone_lib="NIH_MGC_9"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1700
/gene="MKS1"
/gene_synonym="FLJ20345"
/gene_synonym="MES"
/db_xref="GeneID:54903"
/db_xref="HGNC:HGNC:7121"
/db_xref="MIM:609883"
CDS 440..1573
/gene="MKS1"
/gene_synonym="FLJ20345"
/gene_synonym="MES"
/codon_start=1
/product="MKS1 protein"
/protein_id="AAH10061.1"
/db_xref="GeneID:54903"
/db_xref="HGNC:HGNC:7121"
/db_xref="MIM:609883"
/translation="MTTAASEVPSFLVERMANVRRRRQDRRGMEGGILKSRIVTWEPS
EEFVRNNHVINTPLQTMHIMADLGPYKKLGYKKYEHVLCTLKVDSNGVITVKPDFTGL
KGPYRIETEGEKQELWKYTIDNVSPHAQPEEEERERRVFKDLYGRHKEYLSSLVGTDF
EMTVPGALRLFVNGEVVSAQGYEYDNLYVHFFVELPTAHWSSPAFQQLSGVTQTCTTK
SLAMDKVAHFSYPFTFEAFFLHEDESSDALPEWPVLYCEVLSLDFWQRYRVEGYGAVV
LPATPGSHTLTVSTWRPVELGTVAELRRFFIGGSLELEDLSYVRIPGSFKGLSSSKTK
EGRKVDGERVLNPQPVSLSLFPGKPHSTAWGLLRLRYELFLSK"
BASE COUNT 413 a 419 c 464 g 404 t
ORIGIN
1 cgcagctgtc atggcggaga ccgtctggag cactgacacc ggggaggcag tgtatcgctc
61 ccgggacccc gtgcgcaact tgcgcctccg agtccacctg caaagaatca catcaagcaa
121 ctttcttcat tatcagcctg ctgccgagct cgggaaggac ctcatagact tggccacttt
181 taggcctcag ccaactgcca gtggacaccg cccagaggaa gacgaagagg aggagattgt
241 gattgggtgg caggagaagc tctttagcca gtttgaagta gatctgtacc aaaatgaaac
301 agcctgtcag agtcctttgg attatcagta ccgtcaggag atcctgaagc tggagaattc
361 gggtggcaag aaaaaccgac gaatctttac ctacactgac tctgatagat acaccaattt
421 ggaggagcac tgtcagagaa tgaccactgc agccagcgag gtgccttcat tcttggtcga
481 gcgaatggca aatgtcaggc gtcgccggca ggacaggcga gggatggagg gcggcatcct
541 caagtcacgc atcgtcacct gggagccctc agaagagttt gtcaggaaca accacgtcat
601 taacacccct cttcagacaa tgcacatcat ggcagacctg gggccctata aaaagcttgg
661 ctataagaag tatgaacatg tcctgtgtac tctgaaggtg gatagcaatg gtgtgatcac
721 agtaaagcct gacttcacgg gcctcaaagg accctacagg attgagacgg agggggagaa
781 gcaggagctg tggaaatata cgatcgacaa tgtttccccc cacgcacagc cggaggagga
841 ggagcgggaa cggcgagtgt tcaaggatct ttatggccgg cacaaggagt atctcagcag
901 cctcgtaggc accgactttg agatgactgt cccaggtgcc ctccggctct ttgtaaatgg
961 agaggtcgtt tcagcccaag gctatgagta tgacaatctc tacgtccact tctttgtaga
1021 attgccaact gctcactggt caagcccagc attccagcag ctctcaggag taacacagac
1081 ctgcaccacc aagtccctgg caatggacaa ggtggctcac ttctcctacc cattcacgtt
1141 tgaagccttc ttcctccatg aggatgaatc ttctgatgca ctcccggagt ggcctgtgct
1201 ctactgtgag gtcctctcgc tggacttctg gcagaggtac cgtgtggaag gctatggggc
1261 tgtggtgctg cctgccactc caggctcaca caccctgaca gtctccacgt ggagacctgt
1321 ggagcttggc acggtggctg agctgaggag gtttttcatt ggcggttctc tggaactgga
1381 ggacctctcc tatgtacgga taccaggatc cttcaagggc ctttcatctt ccaagaccaa
1441 agaaggaagg aaggtggacg gtgagagggt cttaaatccc cagcctgtga gtctcagcct
1501 ctttccaggg aagcctcatt ctactgcttg gggcttgctg aggttgagat atgagttatt
1561 tctgagtaag tgaaggctga aggcagtgct gagtcctttc tgctagctgg gtggtatctt
1621 ttactgtgtt tttttgtttg tttgtttttt tgttttttgt tacataaacc ccttttattt
1681 tgaaaaaaaa aaaaaaaaaa
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