LOCUS BC009956 1201 bp mRNA linear HUM 11-DEC-2003
DEFINITION Homo sapiens major histocompatibility complex, class II, DP alpha
1, mRNA (cDNA clone MGC:14114 IMAGE:4309471), complete cds.
ACCESSION BC009956
VERSION BC009956.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1201)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1201)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (02-JUL-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC009956.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Louis Staudt
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 20 Row: p Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 24797073.
FEATURES Location/Qualifiers
source 1..1201
/db_xref="H-InvDB:HIT000034691_08"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:14114 IMAGE:4309471"
/tissue_type="Primary B-Cells from Tonsils"
/clone_lib="NIH_MGC_48"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1201
/gene="HLA-DPA1"
/gene_synonym="HLA-DP1A"
/gene_synonym="HLADP"
/gene_synonym="HLASB"
/db_xref="GeneID:3113"
/db_xref="MIM:142880"
CDS 32..814
/gene="HLA-DPA1"
/gene_synonym="HLA-DP1A"
/gene_synonym="HLADP"
/gene_synonym="HLASB"
/codon_start=1
/product="HLA-DPA1 protein"
/protein_id="AAH09956.1"
/db_xref="GeneID:3113"
/db_xref="MIM:142880"
/translation="MRPEDRMFHIRAVILRALSLAFLLSLRGAGAIKADHVSTYAAFV
QTHRPTGEFMFEFDEDEQFYVDLDKKETVWHLEEFGRAFSFEAQGGLANIAILNNNLN
TLIQRSNHTQAANDPPEVTVFPKEPVELGQPNTLICHIDRFFPPVLNVTWLCNGEPVT
EGVAESLFLPRTDYSFHKFHYLTFVPSAEDVYDCRVEHWGLDQPLLKHWEAQEPIQMP
ETTETVLCALGLVLGLVGIIVGTVLIIKSLRSGHDPRAQGPL"
misc_feature 134..376
/gene="HLA-DPA1"
/gene_synonym="HLA-DP1A"
/gene_synonym="HLADP"
/gene_synonym="HLASB"
/note="MHC_II_alpha; Region: Class II histocompatibility
antigen, alpha domain"
/db_xref="CDD:pfam00993"
misc_feature 374..661
/gene="HLA-DPA1"
/gene_synonym="HLA-DP1A"
/gene_synonym="HLADP"
/gene_synonym="HLASB"
/note="IGc; Region: Immunoglobulin domain constant region
subfamily"
/db_xref="CDD:cd00098"
BASE COUNT 319 a 316 c 273 g 293 t
ORIGIN
1 gctcacagtc atcaattata gaccccacaa catgcgccct gaagacagaa tgttccatat
61 cagagctgtg atcttgagag ccctctcctt ggctttcctg ctgagtctcc gaggagctgg
121 ggccatcaag gcggaccatg tgtcaactta tgccgcgttt gtacagaccc atagaccaac
181 aggggagttt atgtttgaat ttgatgaaga tgagcagttc tatgtggatc tggataaaaa
241 ggagaccgtc tggcatctgg aggagtttgg ccgagccttt tcctttgagg ctcagggcgg
301 gctggctaac attgctatat tgaacaacaa cttgaatacc ttgatccagc gttccaacca
361 cactcaggcc gccaatgatc cccctgaggt gaccgtgttt cccaaggagc ctgtggagct
421 gggccagccc aacaccctca tctgccacat tgacaggttc ttcccaccag tgctcaacgt
481 cacatggctg tgcaatgggg agccagtcac tgagggtgtc gctgagagcc tcttcctgcc
541 cagaacagat tacagcttcc acaagttcca ttacctgacc tttgtgccct cagcagagga
601 cgtctatgac tgcagggtgg agcactgggg cttggaccag ccgctcctca agcactggga
661 ggcccaagag ccaatccaga tgcctgagac aacggagact gtgctctgtg ccctgggcct
721 ggtgctgggc ctagtgggca tcatcgtggg caccgtcctc atcataaagt ctctgcgttc
781 tggccatgac ccccgggccc aggggcccct gtgaaatact gtaaaggtga caaaatatct
841 gaacagaaga ggacttagga gagatctgaa ctccagctgc cctacaaact ccgtcacagc
901 ttttcttctc acttcatgtg aaaactaccc cagtggctga ctgaattgct gacccttcaa
961 gctctgtcct tatccgttac cttaaagcag tcattcctta gtaaagtttc caacaaatag
1021 aaattaatga ataaatgttg acactttgat agcactgata tggagattat cctttcattg
1081 agccttttat cctctggtct tctttgaaaa acccctcact gtcaccttcc tgagaatact
1141 ctaagaccaa taaatacttc agtatttcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1201 a
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