LOCUS BC008973 1720 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens transmembrane protein with EGF-like and two
follistatin-like domains 2, mRNA (cDNA clone MGC:17007
IMAGE:4180709), complete cds.
ACCESSION BC008973
VERSION BC008973.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1720)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1720)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: k Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 12383050.
FEATURES Location/Qualifiers
source 1..1720
/db_xref="H-InvDB:HIT000034118"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17007 IMAGE:4180709"
/tissue_type="Brain, anaplastic oligodendroglioma with
1p/19q loss"
/clone_lib="NCI_CGAP_Brn67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1720
/gene="TMEFF2"
/gene_synonym="HPP1"
/gene_synonym="TENB2"
/gene_synonym="TPEF"
/gene_synonym="TR"
/db_xref="GeneID:23671"
/db_xref="HGNC:HGNC:11867"
/db_xref="MIM:605734"
CDS 351..1475
/gene="TMEFF2"
/gene_synonym="HPP1"
/gene_synonym="TENB2"
/gene_synonym="TPEF"
/gene_synonym="TR"
/codon_start=1
/product="transmembrane protein with EGF-like and two
follistatin-like domains 2"
/protein_id="AAH08973.1"
/db_xref="GeneID:23671"
/db_xref="HGNC:HGNC:11867"
/db_xref="MIM:605734"
/translation="MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVKLAAFPTS
LSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPV
CGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKETS
TCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEK
IEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHG
KCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVI
CVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI"
BASE COUNT 449 a 421 c 418 g 432 t
ORIGIN
1 ctccctccac cctgcctcct cgggctccac tcgtctgccc ctggactccc gtctcctcct
61 gtcctccggc ttcccagagc tccctcctta tggcagcagc ttcccgcgtc tccggcgcag
121 cttctcagcg gacgaccctc tcgctccggg gctgagccca gtccctggat gttgctgaaa
181 ctctcgagat catgcgcggg tttggctgct gcttccccgc cgggtgccac tgccaccgcc
241 gccgcctctg ctgccgccgt ccgcgggatg ctcagtagcc cgctgcccgg cccccgcgat
301 cctgtgttcc tcggaagccg tttgctgctg cagagttgca cgaactagtc atggtgctgt
361 gggagtcccc gcggcagtgc agcagctgga cactttgcga gggcttttgc tggctgctgc
421 tgctgcccgt catgctactc atcgtagccc gcccggtgaa gctcgctgct ttccctacct
481 ccttaagtga ctgccaaacg cccaccggct ggaattgctc tggttatgat gacagagaaa
541 atgatctctt cctctgtgac accaacacct gtaaatttga tggggaatgt ttaagaattg
601 gagacactgt gacttgcgtc tgtcagttca agtgcaacaa tgactatgtg cctgtgtgtg
661 gctccaatgg ggagagctac cagaatgagt gttacctgcg acaggctgca tgcaaacagc
721 agagtgagat acttgtggtg tcagaaggat catgtgccac agatgcagga tcaggatctg
781 gagatggagt ccatgaaggc tctggagaaa ctagtcaaaa ggagacatcc acctgtgata
841 tttgccagtt tggtgcagaa tgtgacgaag atgccgagga tgtctggtgt gtgtgtaata
901 ttgactgttc tcaaaccaac ttcaatcccc tctgcgcttc tgatgggaaa tcttatgata
961 atgcatgcca aatcaaagaa gcatcgtgtc agaaacagga gaaaattgaa gtcatgtctt
1021 tgggtcgatg tcaagataac acaactacaa ctactaagtc tgaagatggg cattatgcaa
1081 gaacagatta tgcagagaat gctaacaaat tagaagaaag tgccagagaa caccacatac
1141 cttgtccgga acattacaat ggcttctgca tgcatgggaa gtgtgagcat tctatcaata
1201 tgcaggagcc atcttgcagg tgtgatgctg gttatactgg acaacactgt gaaaaaaagg
1261 actacagtgt tctatacgtt gttcccggtc ctgtacgatt tcagtatgtc ttaatcgcag
1321 ctgtgattgg aacaattcag attgctgtca tctgtgtggt ggtcctctgc atcacaagga
1381 aatgccccag aagcaacaga attcacagac agaagcaaaa tacagggcac tacagttcag
1441 acaatacaac aagagcgtcc acgaggttaa tctaaaggga gcatgtttca cagtggctgg
1501 actaccgaga gcttggacta cacaatacag tattatagac aaaagaataa gacaagagat
1561 ctacacatgt tgccttgcat ttgtggtaat ctacaccaat gaaaacatgt actacagcta
1621 tatttgatta tgtatggata tatttgaaat agtatacatt gtcttgatgt tttttctgta
1681 atgtaaataa actatttata tcacaaaaaa aaaaaaaaaa
//