LOCUS BC008852 3288 bp mRNA linear HUM 11-DEC-2003
DEFINITION Homo sapiens nucleolar protein family 6 (RNA-associated), mRNA
(cDNA clone IMAGE:4100186), partial cds.
ACCESSION BC008852
VERSION BC008852.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3288)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3288)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Dec 9, 2003 this sequence version replaced BC008852.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 26 Row: a Column: 1.
FEATURES Location/Qualifiers
source 1..3288
/db_xref="H-InvDB:HIT000034023"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:4100186"
/tissue_type="Brain, neuroblastoma"
/clone_lib="NIH_MGC_19"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..3288
/gene="NOL6"
/gene_synonym="bA311H10.1"
/gene_synonym="FLJ21959"
/gene_synonym="MGC14896"
/gene_synonym="MGC14921"
/gene_synonym="MGC20838"
/gene_synonym="NRAP"
/db_xref="GeneID:65083"
CDS <1..1935
/gene="NOL6"
/gene_synonym="bA311H10.1"
/gene_synonym="FLJ21959"
/gene_synonym="MGC14896"
/gene_synonym="MGC14921"
/gene_synonym="MGC20838"
/gene_synonym="NRAP"
/codon_start=1
/product="NOL6 protein"
/protein_id="AAH08852.2"
/db_xref="GeneID:65083"
/translation="VSAALGPLTTLLEQGLGARLNLLAHSRPPVPEWDISQDPPKHKD
SGTLTLGLLLRPEGLTSVLELGPEADQPEAAKFRQFWGSRSELRRFQDGAIREAVVWE
AASMSQKRLIPHQVVTHLLALHADIPETCVHYVGGPLDALIQGLKETSSTGEEALVAA
VRCYDDLSRLLWGLEGLPLTVSAVQGAHPVLRYTEVFPPTPVRPAFSFYETLRERSSL
LPRLDKPCPAYVEPMTVVCHLEGSGQWPQDAEAVQRVRAAFQLRLAELLTQQHGLQCR
ATATHTDVLKDGFVFRIRVAYQREPQILKEVQSPEGMISLRDTAASLRLERDTRQLPL
LTSALHGLQQQHPAFSGVARLAKRWVRAQLLGEGFADESLDLVAAALFLHPEPFTPPS
SPQVGFLRFLFLVSTFDWKNNPLFVNLNNELTVEEQVEIRSGFLAARAQLPVMVIVTP
QDRKNSVWTQDGPSAQILQQLVVLAAEALPMLEKQLMDPRGPGDIRTVFRPPLDIYDV
LIRLSPRHIPRHRQAVDSPAASFCRGLLSQPGPSSLMPVLGYDPPQLYLTQLREAFGD
LALFFYDQHGGEVIGVLWKPTSFQPQPFKASSTKGRMVMSRGGELVMVPNVEAILEDF
AVLGEGLVQTVEARSERWTV"
misc_feature 184..1914
/gene="NOL6"
/gene_synonym="bA311H10.1"
/gene_synonym="FLJ21959"
/gene_synonym="MGC14896"
/gene_synonym="MGC14921"
/gene_synonym="MGC20838"
/gene_synonym="NRAP"
/note="Region: Nrap protein. Members of this family are
nucleolar RNA-associated proteins (Nrap) which are highly
conserved from yeast (Saccharomyces cerevisiae) to human.
In the mouse, Nrap is ubiquitously expressed and is
specifically localised in the nucleolus. Nrap is a large
nucleolar protein (of more than 1000 amino acids). Nrap
appears to be associated with ribosome biogenesis by
interacting with pre-rRNA primary transcript"
/db_xref="CDD:pfam03813"
BASE COUNT 692 a 957 c 903 g 736 t
ORIGIN
1 gtctcagctg ctttgggccc cctgaccacc ctcctggagc agggcctggg ggctcggctg
61 aacctgctgg ctcactctcg acccccagtc ccagagtggg acatcagcca agatccacca
121 aagcacaaag actctgggac cctgaccctg ggactccttc tccggcctga gggactgacc
181 agcgtccttg agctgggtcc agaggcagac cagcctgagg ctgctaaatt ccgccagttc
241 tggggatccc gctcggagct tcggcgtttc caggacggag ccattcggga agctgtggtc
301 tgggaggcag cctctatgtc ccagaagcgc cttattcccc accaggtggt cacccacctc
361 ttggcactcc atgctgacat cccagaaacc tgtgtccact atgtgggggg ccccctggat
421 gcacttatcc aaggcctgaa agagacctcc agcacaggtg aggaggccct ggtagcggcg
481 gtacgttgct acgacgacct cagtcgccta ctgtgggggc tagagggtct cccactgacc
541 gtgtctgctg ttcagggagc tcacccagtg ctgcgctaca cagaggtgtt cccaccaact
601 ccagtccgtc cagccttctc cttctatgag actctgcggg agcggtcctc actgctgccc
661 cggctcgata agccctgtcc ggcctacgtg gagcccatga ccgtggtttg tcacctggag
721 ggcagtggcc agtggccaca ggacgctgag gccgtgcagc gggtccgagc tgccttccag
781 ctgcgcctgg cagagctgtt gacacaacag catggtctgc agtgccgtgc cactgccacg
841 cacacggatg tccttaagga tggatttgtg tttcggattc gcgtggccta tcagcgggag
901 ccccagatcc tgaaggaggt gcagagccca gaggggatga tctcgctgag ggacacagct
961 gcctccctcc gccttgagag agacacaagg cagttgccac tgctcaccag tgccctgcac
1021 ggactgcagc agcagcaccc agccttctct ggtgtggcac ggctggccaa gcggtgggtg
1081 cgtgcccagc ttcttggtga gggtttcgct gatgagagcc tggatctggt ggccgctgcc
1141 cttttcctgc accctgagcc cttcacccct ccgagttccc cccaggttgg cttccttcga
1201 ttccttttct tggtatcaac gtttgattgg aagaacaacc ccctctttgt caacctcaat
1261 aatgagctca ctgtggagga gcaggtggag atccgcagtg gcttcctggc agctcgggca
1321 cagctccccg tcatggtcat tgttaccccc caagaccgca aaaactctgt gtggacacag
1381 gatggaccct cagcccagat cctgcagcag cttgtggtcc tggcagctga agccctgccc
1441 atgttagaga agcagctcat ggatccccgg ggacctgggg acatcaggac agtgttccgg
1501 ccgcccttgg acatttacga cgtgctgatt cgcctgtctc ctcgccatat cccgcggcac
1561 cgccaggctg tggactcgcc agctgcctcc ttctgccggg gcctgctcag ccagccgggg
1621 ccctcatccc tgatgcccgt gctgggctat gatcctcctc agctctatct gacgcagctc
1681 agggaggcct ttggggatct ggcccttttc ttctatgacc agcatggtgg agaggtgatt
1741 ggtgtcctct ggaagcccac cagcttccag ccgcagccct tcaaggcctc cagcacaaag
1801 gggcgcatgg tgatgtctcg aggtggggag ctagtaatgg tgcccaatgt tgaagcaatc
1861 ctggaggact ttgctgtgct gggtgaaggc ctggtgcaga ctgtggaggc ccgaagtgag
1921 aggtggactg tgtgatccca gctctggagc aagctgtaga cggacagcag gacattggac
1981 ctctagagca agatgtcagt aggatgacct ccaccctcct tggacatgaa tcctccatgg
2041 agggcctgct ggctgaacat gctgaatcat ctccaacaaa acccagcccc aactttctct
2101 ctgatgctcc agcattgggg caggggcatg gtggcccatg tagtctcctg ggcctcacca
2161 tcccagaaga ggagtgggag ccagctcaga gaaggaactg aacccaggag atccatccac
2221 ctattagccc tgggcctgga cctccctgcg atttcccact cctttcttag tcttcttcca
2281 gaaacagaga aggggatgtg tgcctgggag aggctctgtc tccttcctgc tgccaggacc
2341 tgtgcctaga cttagcatgc ccttcactgc agtgtcaggc ctttagatgg gacccagcga
2401 aaatgtggcc cttctgagtc acatcaccga cactgagcag tggaaagggg ctatatgtgt
2461 atgaatagac cacattgaag gagcacaatg ccctcctgtg ttgatgccac ttcccagggt
2521 ggagacagtg gaaaagaacc gaggacagga aaggattggg taggtgaagg ggtcagggga
2581 ctggtagtca cccaatcttg gagaggtgca aaaagcactg ggggctaccc gttagctgca
2641 tctgccctgg ctgtttgccc gttcatgtca caaactgcca ctactatgta cctgcagtgg
2701 ggttgcagag atgggggaga ctcaagtctt actccccagg agctcccagg gcccaaggag
2761 gagaatgctg cctcctttca gtctggtcta cacccacttt ctggtagcct ctctgcttcc
2821 tgtaattctg gctgtttttc cagactcagc tcaaatagtg cccctcctta agcccatccc
2881 tcgcccccag cctgaggtga tctttccctc ctctgaacta ttagagcagt tactgtctgt
2941 tcagttcgtt tggcaggcac acacagtggc ataaattcta ttgttttgaa ctctgattta
3001 aaattaaatt gcagctgggc gtggtggctt atgcttgtaa tcccaacact tagggagtca
3061 ggagaatcac ttgagctcag gagttctaga ccaatctggg caacagagag accccatctc
3121 ttttaaataa aaagttaaat tgcttaattt cccccgtatt cctggcctgt ctgccccttt
3181 cacataattt taacctggtt tcttgtatgt aaactccttg agggcaagaa catgtttgaa
3241 catagaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//