LOCUS BC008764 2823 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens kinesin family member 2C, mRNA (cDNA clone MGC:1266
IMAGE:3347571), complete cds.
ACCESSION BC008764
VERSION BC008764.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2823)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2823)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC008764.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 5 Row: h Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 13699832.
FEATURES Location/Qualifiers
source 1..2823
/db_xref="H-InvDB:HIT000033952"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1266 IMAGE:3347571"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2823
/gene="KIF2C"
/gene_synonym="MCAK"
/db_xref="GeneID:11004"
/db_xref="HGNC:HGNC:6393"
/db_xref="MIM:604538"
CDS 55..2232
/gene="KIF2C"
/gene_synonym="MCAK"
/codon_start=1
/product="kinesin family member 2C"
/protein_id="AAH08764.1"
/db_xref="GeneID:11004"
/db_xref="HGNC:HGNC:6393"
/db_xref="MIM:604538"
/translation="MAMDSSLQARLFPGLAIKIQRSNGLIHSANVRTVNLEKSCVSVE
WAEGGATKGKEIDFDDVAAINPELLQLLPLHPKDNLPLQENVTIQKQKRRSVNSKIPA
PKESLRSRSTRMSTVSELRITAQENDMEVELPAAANSRKQFSVPPAPTRPSCPAVAEI
PLRMVSEEMEEQVHSIRGSSSANPVNSVRRKSCLVKEVEKMKNKREEKKAQNSEMRMK
RAQEYDSSFPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKK
EIDVISIPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQ
TIFEGGKATCFAYGQTGSGKTHTMGGDLSGKAQNASKGIYAMASRDVFLLKNQPCYRK
LGLEVYVTFFEIYNGKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMID
MGSACRTSGQTFANSNSSRSHACFQIILRAKGRMHGKFSLVDLAGNERGADTSSADRQ
TRMEGAEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATIS
PGISSCEYTLNTLRYADRVKELSPHSGPSGEQLIQMETEEMEACSNGALIPGNLSKEE
EELSSQMSSFNEAMTQIRELEEKAMEELKEIIQQGPDWLELSEMTEQPDYDLETFVNK
AESALAQQAKHFSALPDVIKALRLAMQLEEQASRQISSKKRPQ"
BASE COUNT 774 a 668 c 733 g 648 t
ORIGIN
1 gcgaaattga ggtttcttgg tattgcgcgt ttctcttcct tgctgactct ccgaatggcc
61 atggactcgt cgcttcaggc ccgcctgttt cccggtctcg ctatcaagat ccaacgcagt
121 aatggtttaa ttcacagtgc caatgtaagg actgtgaact tggagaaatc ctgtgtttca
181 gtggaatggg cagaaggagg tgccacaaag ggcaaagaga ttgattttga tgatgtggct
241 gcaataaacc cagaactctt acagcttctt cccttacatc cgaaggacaa tctgcccttg
301 caggaaaatg taacaatcca gaaacaaaaa cggagatccg tcaactccaa aattcctgct
361 ccaaaagaaa gtcttcgaag ccgctccact cgcatgtcca ctgtctcaga gcttcgcatc
421 acggctcagg agaatgacat ggaggtggag ctgcctgcag ctgcaaactc ccgcaagcag
481 ttttcagttc ctcctgcccc cactaggcct tcctgccctg cagtggctga aataccattg
541 aggatggtca gcgaggagat ggaagagcaa gtccattcca tccgaggcag ctcttctgca
601 aaccctgtga actcagttcg gaggaaatca tgtcttgtga aggaagtgga aaaaatgaag
661 aacaagcgag aagagaagaa ggcccagaac tctgaaatga gaatgaagag agctcaggag
721 tatgacagta gttttccaaa ctgggaattt gcccgaatga ttaaagaatt tcgggctact
781 ttggaatgtc atccacttac tatgactgat cctatcgaag agcacagaat atgtgtctgt
841 gttaggaaac gcccactgaa taagcaagaa ttggccaaga aagaaattga tgtgatttcc
901 attcctagca agtgtctcct cttggtacat gaacccaagt tgaaagtgga cttaacaaag
961 tatctggaga accaagcatt ctgctttgac tttgcatttg atgaaacagc ttcgaatgaa
1021 gttgtctaca ggttcacagc aaggccactg gtacagacaa tctttgaagg tggaaaagca
1081 acttgttttg catatggcca gacaggaagt ggcaagacac atactatggg cggagacctc
1141 tctgggaaag cccagaatgc atccaaaggg atctatgcca tggcctcccg ggacgtcttc
1201 ctcctgaaga atcaaccctg ctaccggaag ttgggcctgg aagtctatgt gacattcttc
1261 gagatctaca atgggaagct gtttgacctg ctcaacaaga aggccaagct gcgcgtgctg
1321 gaggacggca agcaacaggt gcaagtggtg gggctgcagg agcatctggt taactctgct
1381 gatgatgtca tcaagatgat cgacatgggc agcgcctgca gaacctctgg gcagacattt
1441 gccaactcca attcctcccg ctcccacgcg tgcttccaaa ttattcttcg agctaaaggg
1501 agaatgcatg gcaagttctc tttggtagat ctggcaggga atgagcgagg cgcggacact
1561 tccagtgctg accggcagac ccgcatggag ggcgcagaaa tcaacaagag tctcttagcc
1621 ctgaaggagt gcatcagggc cctgggacag aacaaggctc acaccccgtt ccgtgagagc
1681 aagctgacac aggtgctgag ggactccttc attggggaga actctaggac ttgcatgatt
1741 gccacgatct caccaggcat aagctcctgt gaatatactt taaacaccct gagatatgca
1801 gacagggtca aggagctgag cccccacagt gggcccagtg gagagcagtt gattcaaatg
1861 gaaacagaag agatggaagc ctgctctaac ggggcgctga ttccaggcaa tttatccaag
1921 gaagaggagg aactgtcttc ccagatgtcc agctttaacg aagccatgac tcagatcagg
1981 gagctggagg agaaggctat ggaagagctc aaggagatca tacagcaagg accagactgg
2041 cttgagctct ctgagatgac cgagcagcca gactatgacc tggagacctt tgtgaacaaa
2101 gcggaatctg ctctggccca gcaagccaag catttctcag ccctgccaga tgtcatcaag
2161 gccttgcgcc tggccatgca gctggaagag caggctagca gacaaataag cagcaagaaa
2221 cggccccagt gacgactgca aataaaaatc tgtttggttt gacacccagc ctcttccctg
2281 gccctcccca gagaactttg ggtacctggt gggtctaggc agggtctgag ctgggacagg
2341 ttctggtaaa tgccaagtat gggggcatct gggcccaggg cagctgggga gggggtcaga
2401 gtgacatggg acactccttt tctgttcctc agttgtcgcc ctcacgagag gaaggagctc
2461 ttagttaccc ttttgtgttg cccttctttc catcaagggg aatgttctca gcatagagct
2521 ttctccgcag catcctgcct gcgtggactg gctgctaatg gagagctccc tggggttgtc
2581 ctggctctgg ggagagagac ggagccttta gtacagctat ctgctggctc taaaccttct
2641 acgcctttgg gccgagcact gaatgtcttg tactttaaaa aaatgtttct gagacctctt
2701 tctactttac tgtctcccta gagatcctag aggatcccta ctgttttctg ttttatgtgt
2761 ttatacattg tatgtaacaa taaagagaaa aaataaaaaa aaaaaaaaaa aaaaaaaaaa
2821 aaa
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