LOCUS BC008692 1892 bp mRNA linear HUM 04-AUG-2008
DEFINITION Homo sapiens protein tyrosine phosphatase, non-receptor type 11,
mRNA (cDNA clone MGC:17206 IMAGE:3872007), complete cds.
ACCESSION BC008692
VERSION BC008692.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1892)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1892)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 13 Row: k Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 33356176.
FEATURES Location/Qualifiers
source 1..1892
/db_xref="H-InvDB:HIT000033905"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17206 IMAGE:3872007"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1892
/gene="PTPN11"
/gene_synonym="BPTP3"
/gene_synonym="CFC"
/gene_synonym="PTP-1D"
/gene_synonym="PTP2C"
/gene_synonym="SH-PTP2"
/gene_synonym="SH-PTP3"
/gene_synonym="SHP2"
/db_xref="GeneID:5781"
/db_xref="HGNC:HGNC:9644"
/db_xref="MIM:176876"
CDS 204..1586
/gene="PTPN11"
/gene_synonym="BPTP3"
/gene_synonym="CFC"
/gene_synonym="PTP-1D"
/gene_synonym="PTP2C"
/gene_synonym="SH-PTP2"
/gene_synonym="SH-PTP3"
/gene_synonym="SHP2"
/codon_start=1
/product="PTPN11 protein"
/protein_id="AAH08692.1"
/db_xref="GeneID:5781"
/db_xref="HGNC:HGNC:9644"
/db_xref="MIM:176876"
/translation="MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLS
VRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL
NCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGES
NDGKSKVTHVMIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNT
TRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNK
NRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCL
QNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESA
AHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIM
DAGPVVVHCR"
BASE COUNT 564 a 421 c 498 g 409 t
ORIGIN
1 gcggaggagg agcgagccgg gccggggggc agctgcacag tctccgggat ccccaggcct
61 ggaggggggt ctgtgcgcgg ccggctggct ctgccccgcg tccggtcccg agcgggcctc
121 cctcgggcca gcccgatgtg accgagccca gcggagcctg agcaaggagc gggtccgtcg
181 cggagccgga gggcgggagg aacatgacat cgcggagatg gtttcaccca aatatcactg
241 gtgtggaggc agaaaaccta ctgttgacaa gaggagttga tggcagtttt ttggcaaggc
301 ctagtaaaag taaccctgga gacttcacac tttccgttag aagaaatgga gctgtcaccc
361 acatcaagat tcagaacact ggtgattact atgacctgta tggaggggag aaatttgcca
421 ctttggctga gttggtccag tattacatgg aacatcacgg gcaattaaaa gagaagaatg
481 gagatgtcat tgagcttaaa tatcctctga actgtgcaga tcctacctct gaaaggtggt
541 ttcatggaca tctctctggg aaagaagcag agaaattatt aactgaaaaa ggaaaacatg
601 gtagttttct tgtacgagag agccagagcc accctggaga ttttgttctt tctgtgcgca
661 ctggtgatga caaaggggag agcaatgacg gcaagtctaa agtgacccat gttatgattc
721 gctgtcagga actgaaatac gacgttggtg gaggagaacg gtttgattct ttgacagatc
781 ttgtggaaca ttataagaag aatcctatgg tggaaacatt gggtacagta ctacaactca
841 agcagcccct taacacgact cgtataaatg ctgctgaaat agaaagcaga gttcgagaac
901 taagcaaatt agctgagacc acagataaag tcaaacaagg cttttgggaa gaatttgaga
961 cactacaaca acaggagtgc aaacttctct acagccgaaa agagggtcaa aggcaagaaa
1021 acaaaaacaa aaatagatat aaaaacatcc tgccctttga tcataccagg gttgtcctac
1081 acgatggtga tcccaatgag cctgtttcag attacatcaa tgcaaatatc atcatgcctg
1141 aatttgaaac caagtgcaac aattcaaagc ccaaaaagag ttacattgcc acacaaggct
1201 gcctgcaaaa cacggtgaat gacttttggc ggatggtgtt ccaagaaaac tcccgagtga
1261 ttgtcatgac aacgaaagaa gtggagagag gaaagagtaa atgtgtcaaa tactggcctg
1321 atgagtatgc tctaaaagaa tatggcgtca tgcgtgttag gaacgtcaaa gaaagcgccg
1381 ctcatgacta tacgctaaga gaacttaaac tttcaaaggt tggacaaggg aatacggaga
1441 gaacggtctg gcaataccac tttcggacct ggccggacca cggcgtgccc agcgaccctg
1501 ggggcgtgct ggacttcctg gaggaggtgc accataagca ggagagcatc atggatgcag
1561 ggccggtcgt ggtgcactgc aggtgacagc tcctgctgcc cctctaggcc acagcctgtc
1621 cctgtctcct agcgcccagg gcttgctttt acctacccac tcctagctct ttaactgtag
1681 gaagaattta atatctgttt gaggcataga gcaactgcat tgagggacat tttgatccca
1741 aggcatattt ctcctagacc ctacagcact gccattggcc atggccatgg caacatgctc
1801 agttaaaaca gcaaagacta agtcagcatt atctctgagt ccaccagaag ttgtgcatta
1861 aacaacttca tcctggaaaa aaaaaaaaaa aa
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