LOCUS BC008585 1434 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens major histocompatibility complex, class II, DQ alpha
1, mRNA (cDNA clone MGC:17213 IMAGE:4339446), complete cds.
ACCESSION BC008585
VERSION BC008585.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1434)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1434)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Lou Staudt
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: p Column: 15
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 18426974.
FEATURES Location/Qualifiers
source 1..1434
/db_xref="H-InvDB:HIT000033847_04"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17213 IMAGE:4339446"
/tissue_type="Lymph, lymphoma"
/clone_lib="NIH_MGC_85"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1434
/gene="HLA-DQA1"
/gene_synonym="CELIAC1"
/gene_synonym="DQA1"
/gene_synonym="HLA-DQ"
/gene_synonym="HLA-DQA"
/db_xref="GeneID:3117"
/db_xref="MIM:146880"
CDS 35..799
/gene="HLA-DQA1"
/gene_synonym="CELIAC1"
/gene_synonym="DQA1"
/gene_synonym="HLA-DQ"
/gene_synonym="HLA-DQA"
/codon_start=1
/product="HLA-DQA1 protein"
/protein_id="AAH08585.1"
/db_xref="GeneID:3117"
/db_xref="MIM:146880"
/translation="MILNKALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGP
SGQYTHEFDGDEQFYVDLGRKETVWCLPVLRQFRFDPQFALTNIAVLKHNLNSLIKRS
NSTAATNEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSET
SFLSKSDHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPEIPAPMSELTETV
VCALGLSVGLVGIVVGTVFIIRGLRSVGASRHQGPL"
misc_feature 119..361
/gene="HLA-DQA1"
/gene_synonym="CELIAC1"
/gene_synonym="DQA1"
/gene_synonym="HLA-DQ"
/gene_synonym="HLA-DQA"
/note="MHC_II_alpha; Region: Class II histocompatibility
antigen, alpha domain"
/db_xref="CDD:pfam00993"
misc_feature 413..628
/gene="HLA-DQA1"
/gene_synonym="CELIAC1"
/gene_synonym="DQA1"
/gene_synonym="HLA-DQ"
/gene_synonym="HLA-DQA"
/note="IGc1; Region: Immunoglobulin C-Type"
/db_xref="CDD:smart00407"
BASE COUNT 353 a 374 c 299 g 408 t
ORIGIN
1 gaacagcaac tgctaaggct gccttgggaa gaggatgatc ctaaacaaag ctctgatgct
61 gggggccctt gccctgacca ccgtgatgag cccctgtgga ggtgaagaca ttgtggctga
121 ccacgtcgcc tcttatggtg taaacttgta ccagtcttac ggtccctctg gccagtacac
181 ccatgaattt gatggagatg agcagttcta cgtggacctg gggaggaagg agactgtctg
241 gtgtttgcct gttctcagac aatttagatt tgacccgcaa tttgcactga caaacatcgc
301 tgtcctaaaa cataacttga acagtctgat taaacgctcc aactctaccg ctgctaccaa
361 tgaggttcct gaggtcacag tgttttccaa gtctcccgtg acactgggtc agcccaacat
421 cctcatctgt cttgtggaca acatctttcc tcctgtggtc aacatcacat ggctgagcaa
481 tgggcactca gtcacagaag gtgtttctga gaccagcttc ctctccaaga gtgatcattc
541 cttcttcaag atcagttacc tcaccctcct cccttctgct gaggagagtt atgactgcaa
601 ggtggagcac tggggcctgg acaagcctct tctgaaacac tgggagcctg agattccagc
661 ccctatgtca gagctcacag agactgtggt ctgcgccctg ggattgtctg tgggcctcgt
721 gggcattgtg gtgggcactg tcttcatcat ccgaggcctg cgttcagttg gtgcttccag
781 acaccaaggg cccttgtgaa tcccatcctg gaatggaagg tgcatcgcca tctacaggag
841 cagaagagtg gacttgctac atgacctagc attattttct ggccccattt atcatatccc
901 ttttctcctc caaatgtttc tcctctcacc tcttctgtgg gacttaaatt gctatatctg
961 ctcagagctc acaaatgcct ttgaattatt tccctgactt cctgattttt ttcttcttaa
1021 gtgttaccta ctaagagttg cctggagtaa gccacccagc tacctaattc ctcagtaacc
1081 tccatctata atctccatgg aagcaacaaa ttccctttat gagatatatg tcaaattttt
1141 ccatctttca tccagggctg actgaaaccg tggctaagaa ttgggagact ctcttgtttc
1201 aagccaattt aacatcattt accagatcat ttgtcatgtc cagtaacaca gaagcaacca
1261 actacagtat agcctgataa catgatttct tagctgacat taatatttct ttcttccttg
1321 tgttcccacc cttggcattg ccacccaccc ctcaattaag gcaacaatga agttaatgga
1381 taccctctgc ctttggctca gaaatgttat agcaaaaatt ttaaaaaaaa aaaa
//