LOCUS BC008185 1039 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens hydroxysteroid (17-beta) dehydrogenase 8, mRNA (cDNA
clone MGC:17181 IMAGE:4213813), complete cds.
ACCESSION BC008185
VERSION BC008185.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1039)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1039)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: David N. Louis, M.D.
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Baylor College of Medicine Human Genome
Sequencing Center
Center code: BCM-HGSC
Web site: http://www.hgsc.bcm.tmc.edu/cdna/
Contact: amg@bcm.tmc.edu
Gunaratne, P.H., Garcia, A.M., Lu, X., Hulyk, S.W., Loulseged, H.,
Kowis, C.R., Sneed, A.J., Martin, R.G., Muzny, D.M., Nanavati,
A.N., Gibbs, R.A.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 12 Row: n Column: 20
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 20143980.
FEATURES Location/Qualifiers
source 1..1039
/db_xref="H-InvDB:HIT000033662_09"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:17181 IMAGE:4213813"
/tissue_type="Brain, glioblastoma with EGFR amplification"
/clone_lib="NCI_CGAP_Brn64"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..1039
/gene="HSD17B8"
/gene_synonym="D6S2245E"
/gene_synonym="dJ1033B10.9"
/gene_synonym="FABG"
/gene_synonym="H2-KE6"
/gene_synonym="HKE6"
/gene_synonym="KE6"
/gene_synonym="RING2"
/db_xref="GeneID:7923"
/db_xref="HGNC:HGNC:3554"
/db_xref="MIM:601417"
CDS 28..813
/gene="HSD17B8"
/gene_synonym="D6S2245E"
/gene_synonym="dJ1033B10.9"
/gene_synonym="FABG"
/gene_synonym="H2-KE6"
/gene_synonym="HKE6"
/gene_synonym="KE6"
/gene_synonym="RING2"
/codon_start=1
/product="hydroxysteroid (17-beta) dehydrogenase 8"
/protein_id="AAH08185.1"
/db_xref="GeneID:7923"
/db_xref="HGNC:HGNC:3554"
/db_xref="MIM:601417"
/translation="MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLD
RAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVS
CAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIVGK
VGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKI
TEMIPMGHLGDPEDVADVVAFLASEDSGYITGTSVEVTGGLFM"
BASE COUNT 268 a 275 c 303 g 193 t
ORIGIN
1 gggattccca cccacccaca gcccgccatg gcgtctcagc tccagaaccg actccgctcc
61 gcactggcct tggtcacagg tgcggggagc ggcatcggcc gagcggtcag tgtacgcctg
121 gccggagagg gggccaccgt agctgcctgc gacctggacc gggcagcggc acaggagacg
181 gtgcggctgc tgggcgggcc agggagcaag gaggggccgc cccgagggaa ccatgctgcc
241 ttccaggctg acgtgtctga ggccagggcc gccaggtgcc tgctggaaca agtgcaggcc
301 tgcttttctc gcccaccatc tgtcgttgtg tcctgtgcgg gcatcaccca ggatgagttt
361 ctgctgcaca tgtctgagga tgactgggac aaagtcatag ctgtcaacct caagggcacc
421 ttcctagtca ctcaggctgc agcacaagcc ctggtgtcca atggttgtcg tggttccatc
481 atcaacatca gtagcatcgt aggaaaggtg gggaacgtgg ggcagacaaa ctatgcagca
541 tccaaggctg gagtgattgg gctgacccag accgcagccc gggagcttgg acgacatggg
601 atccgctgta actctgtcct cccagggttc attgcaacac ccatgacaca gaaagtgcca
661 cagaaagtgg tggacaagat tactgaaatg atcccgatgg gacacttggg ggaccctgag
721 gatgtggcag atgtggtcgc attcttggca tctgaagata gtggatacat cacagggacc
781 tcagtggaag tcactggagg tcttttcatg taactgcctc aaggaccctg gactctgctc
841 acccccccac cactctgcct ggcctcctgc tgatgaggac tctaagttcc caggatacaa
901 aaggggtggc agtgtatggt tcaggaatgc tgaatatggg aagcaggggt gcttgtgacc
961 ctaataaatt ccaagtcctc taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
1021 aaaaaaaaaa aaaaaaaaa
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