LOCUS BC008002 2176 bp mRNA linear HUM 07-NOV-2006
DEFINITION Homo sapiens pleckstrin homology domain containing, family M (with
RUN domain) member 2, mRNA (cDNA clone IMAGE:3507149), partial cds.
ACCESSION BC008002
VERSION BC008002.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2176)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2176)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 23 Row: e Column: 6
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..2176
/db_xref="H-InvDB:HIT000086980"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:3507149"
/tissue_type="Kidney, renal cell adenocarcinoma"
/clone_lib="NIH_MGC_14"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene <1..2176
/gene="PLEKHM2"
/gene_synonym="KIAA0842"
/gene_synonym="RP11-169K16.1"
/gene_synonym="SKIP"
/db_xref="GeneID:23207"
/db_xref="HGNC:HGNC:29131"
/db_xref="MIM:609613"
CDS <1..1324
/gene="PLEKHM2"
/gene_synonym="KIAA0842"
/gene_synonym="RP11-169K16.1"
/gene_synonym="SKIP"
/codon_start=2
/product="PLEKHM2 protein"
/protein_id="AAH08002.1"
/db_xref="GeneID:23207"
/db_xref="HGNC:HGNC:29131"
/db_xref="MIM:609613"
/translation="MVHSSEFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNL
QLLYVLLTDCYVYLLRKGATEKPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQF
LLDTADVALAEFFLASLKSAMIKGCREPPYPSILTDATMEKLALAKFVAQESKCEASA
VTVRFYGLVHWEDPTDESLGPTPCHCSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFV
VLSNGILYQYPDRTDVIPLLSVNMGGEQCGGCRRANTTDRPHAFQVILSDRPCLELSA
ESEAEMAEWMQHLCQAVSKGVIPQGVAPSPCIPCCLVLTDDRLFTCHEDCQTSFFRSL
GTAKLGDISAVSTEPGKEYCVLEFSQDSQQLLPPWVIYLSCTSELDRLLSALNSGWKT
IYQVDLPHTAIQEASNKKKFEDALSLIHSAWQRSDSLCRGRASRDPWC"
BASE COUNT 442 a 678 c 639 g 417 t
ORIGIN
1 gatggtccat tcctcggagt tcagagtaga caacaatcac ctgctcctgc tcatgatcca
61 cgtgttccga gaaaacgaag agcagctgtt caaaatgatc cggatgagca ccgggcacat
121 ggagggcaac ctgcagctgc tgtacgtgct gctcacagac tgctatgtct acctgctccg
181 gaaaggggcc acagagaagc catacctggt ggaagaggcc gtttcttaca atgaacttga
241 ctatgtgtcg gttggccttg accagcagac ggtgaagctg gtgtgcacca accgcaggaa
301 gcagtttctg ctggacacgg ctgatgtggc gctggctgag ttctttttgg cttctttgaa
361 gtcagccatg atcaaaggct gtcgagaacc tccctacccc agcatcctga cggatgccac
421 catggagaag ctggcactgg ccaaatttgt ggcccaagaa tcgaagtgtg aggcatctgc
481 tgtcaccgtg cgcttctacg gccttgtgca ctgggaggac cccacagacg agtccctggg
541 ccccacgccc tgccactgct caccccccga gggcaccatc accaaagaag gcatgctgca
601 ctacaaggcg ggcacctcct acctgggcaa ggaacactgg aagacgtgct tcgtggtgct
661 cagcaacggg atcctctacc agtacccgga ccgcaccgac gtcatccctc tgctctcggt
721 gaacatgggg ggggagcagt gcggtggctg ccggagagcc aacaccacgg atcggcccca
781 cgccttccag gtcattctct ccgaccggcc ctgcctggag ctaagtgccg agagcgaggc
841 cgagatggcc gagtggatgc agcatctctg ccaggctgtg tccaaagggg tcatccccca
901 gggcgtagct cccagcccct gcataccctg ctgcctggtc ctcacggatg accgcctctt
961 tacgtgccat gaggattgcc agaccagctt cttccgctct ttgggcacag ccaagctggg
1021 cgacatcagc gccgtctcca ccgagccggg caaggagtac tgcgtcttgg agttctccca
1081 ggacagccag cagctcctcc cgccctgggt catctacctg agctgcactt ctgaactgga
1141 ccgattgctg tctgcactga actctgggtg gaaaaccatc tatcaggtgg acctccccca
1201 cacggcgatc caggaagcct ccaacaagaa gaaattcgag gatgccttga gcctcatcca
1261 cagcgcctgg cagcggagcg acagtctctg ccgcggccga gcctcccgag acccctggtg
1321 ctgaggcaga gctggttggc gtccctggtg ggcaggaaag gaaggcacgc cagccggcag
1381 gcacactgtc acggctgttg tcatgctgtc gggagcctac agtccacccc tgccctgggc
1441 ggcagaacca ccgagtgtgg cttaagacag ggtccctcca ctccagggat ccagatcagg
1501 tgcccggcac ccctgggcat cctgcccgac aggtagcgaa tggaggtcgc tgggggcaga
1561 gggtccgagc cctgtgggct ctgcggatgc acgccctcct cccgggcctc cgcctcagtc
1621 tgcagaattt ctgccgagtg gcaccgagaa caccatccat ctaaggacga acaaaagaac
1681 caggagggcg ggacccccct cttcctctcc tgggttgggg gctggggccc tgagtgccca
1741 gccatccttg ttcgtgtttg aacactctcc tggccacgtg gggaagcggg aacacggggt
1801 gtctgcgcat gtttcctcct cctagctcca tcactgcgca cacagctgcc tgcctcgcca
1861 gatgcagggg ggcgggcagc cctccctggc tgccaggagg ctctgcatgc ccacagtcct
1921 gccctgcctg tcccctcaac ccggcagtgc ctgtagcacc gaggagcaaa gggggtggat
1981 ggggggcttg gagaagggcg gagcccacca gcctggcatc catgttgaca tcttctgact
2041 gtcccctgct tggctggagc caggcccttc cctagagttt cgtcaagagc ctcctgggga
2101 aggggtcagg tggtttgggt tttgtttttt aaaataaaat agacatgtta tattgcaaaa
2161 aaaaaaaaaa aaaaaa
//