LOCUS BC007888 1239 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens eukaryotic translation initiation factor 2, subunit 2
beta, 38kDa, mRNA (cDNA clone MGC:14174 IMAGE:4120898), complete
cds.
ACCESSION BC007888
VERSION BC007888.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1239)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1239)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (11-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Aug 19, 2003 this sequence version replaced BC007888.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 20 Row: d Column: 23.
FEATURES Location/Qualifiers
source 1..1239
/db_xref="H-InvDB:HIT000033514"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:14174 IMAGE:4120898"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1239
/gene="EIF2S2"
/gene_synonym="EIF2"
/gene_synonym="EIF2B"
/gene_synonym="EIF2beta"
/gene_synonym="MGC8508"
/db_xref="GeneID:8894"
/db_xref="MIM:603908"
CDS 285..929
/gene="EIF2S2"
/gene_synonym="EIF2"
/gene_synonym="EIF2B"
/gene_synonym="EIF2beta"
/gene_synonym="MGC8508"
/codon_start=1
/product="EIF2S2 protein"
/protein_id="AAH07888.1"
/db_xref="GeneID:8894"
/db_xref="MIM:603908"
/translation="MLGNKKKKKKNVKFPDEDEILEKDEALEDEDNKKDDGISFSNQT
GPAWAGSERDYTYEELLNRVFNIMREKNPDMVAGEKRKFVMKPPQVVRVGTKKTSFVN
FTDICKLLHRQPKHLLAFLLAELGTSGSIDGNNQLVIKGRFQQKQIENVLRRYIKEYV
TCHTCRSPDTILQKDTRLYFLQCETCHSRCSVASIKTGFQAVTGKRAQLRAKAN"
misc_feature 489..857
/gene="EIF2S2"
/gene_synonym="EIF2"
/gene_synonym="EIF2B"
/gene_synonym="EIF2beta"
/gene_synonym="MGC8508"
/note="eIF5_eIF2B; Region: Domain found in IF2B/IF5. This
family includes the N terminus of eIF-5, and the C
terminus of eIF-2 beta. This region corresponds to the
whole of the archaebacterial eIF-2 beta homolog. The
region contains a putative zinc binding C4 finger"
/db_xref="CDD:pfam01873"
BASE COUNT 456 a 211 c 275 g 297 t
ORIGIN
1 gaagaggaca ctaggaaaaa agatgcttcc aaacccagcc ttcagaaaca aaagaagtgg
61 agccagagcc aactgaggac aaggatttgg aagctgatga agaggacact aggaaaaaag
121 atgcttctga tgatctagat gacttgaact tctttaatca aaagaaaaag aagaaaaaaa
181 ctaaaaagat atttgatatt gatgaagctg aagaaggtgt aaaggatctt aagattgaaa
241 gtgatgttca agaaccaact gaaccagagg atgaccttga cattatgctt ggcaataaaa
301 agaagaaaaa gaagaatgtt aagttcccag atgaggatga aatactagag aaagatgaag
361 ctctagaaga tgaagacaac aaaaaagatg atggtatctc attcagtaat cagacaggcc
421 ctgcttgggc aggctcagaa agagactaca catacgagga gctgctgaat cgagtgttca
481 acatcatgag ggaaaagaat ccagatatgg ttgctgggga gaaaaggaaa tttgtcatga
541 aacctccaca agtcgtccga gtaggaacca agaaaacttc ttttgtcaac tttacagata
601 tctgtaaact attacatcgt cagcccaaac atctccttgc atttttgttg gctgaattgg
661 gtacaagtgg ttctatagat ggtaataacc aacttgtaat caaaggaaga ttccaacaga
721 aacagataga aaatgtcttg agaagatata tcaaggaata tgtcacttgt cacacatgcc
781 gatcaccgga cacaatcctg cagaaggaca cacgactcta tttcctacag tgcgaaactt
841 gtcattctag atgttctgtt gccagtatca aaaccggctt ccaggctgtc acgggcaagc
901 gagcacagct ccgtgccaaa gctaactaat ttgctaatca ctgattttgc aaagcttgtt
961 gtggagatgt ggctggacag gtttgccatc agagtggata taccgttgta ttaaaaacaa
1021 gataaaaaag ctgccaagat ttttggcgag tggttggtct gaagtccttg caagacgctg
1081 atgctcaagc tgttgacata ctcattgcct actttaacac ctgtcagaga aacgtgatat
1141 ggggtaagga ggtgcttttt taaaatcgtt catagacttc tgtaaaatgc aagataaatt
1201 aaagttatta taacagtgaa aaaaaaaaaa aaaaaaaaa
//