LOCUS BC007491 3238 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens exonuclease 1, mRNA (cDNA clone MGC:1908
IMAGE:2967734), complete cds.
ACCESSION BC007491
VERSION BC007491.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3238)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3238)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Oct 8, 2003 this sequence version replaced BC007491.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 3 Row: a Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 39995068.
FEATURES Location/Qualifiers
source 1..3238
/db_xref="H-InvDB:HIT000033246"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:1908 IMAGE:2967734"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..3238
/gene="EXO1"
/gene_synonym="HEX1"
/gene_synonym="hExoI"
/db_xref="GeneID:9156"
/db_xref="HGNC:HGNC:3511"
/db_xref="MIM:606063"
CDS 531..3071
/gene="EXO1"
/gene_synonym="HEX1"
/gene_synonym="hExoI"
/codon_start=1
/product="exonuclease 1"
/protein_id="AAH07491.1"
/db_xref="GeneID:9156"
/db_xref="HGNC:HGNC:3511"
/db_xref="MIM:606063"
/translation="MGIQGLLQFIKEASEPIHVRKYKGQVVAVDTYCWLHKGAIACAE
KLAKGEPTDRYVGFCMKFVNMLLSHGIKPILVFDGCTLPSKKEVERSRRERRQANLLK
GKQLLREGKVSEARECFTRSINITHAMAHKVIKAARSQGVDCLVAPYEADAQLAYLNK
AGIVQAIITEDSDLLAFGCKKVILKMDQFGNGLEIDQARLGMCRQLGDVFTEEKFRYM
CILSGCDYLSSLRGIGLAKACKVLRLANNPDIVKVIKKIGHYLKMNITVPEDYINGFI
RANNTFLYQLVFDPIKRKLIPLNAYEDDVDPETLSYAGQYVDDSIALQIALGNKDINT
FEQIDDYNPDTAMPAHSRSHSWDDKTCQKSANVSSIWHRNYSPRPESGTVSDAPQLKE
NPSTVGVERVISTKGLNLPRKSSIVKRPRSAELSEDDLLSQYSLSFTKKTKKNSSEGN
KSLSFSEVFVPDLVNGPTNKKSVSTPPRTRNKFATFLQRKNEESGAVVVPGTRSRFFC
SSDSTDCVSNKVSIQPLDETAVTDKENNLHESEYGDQEGKRLVDTDVARNSSDDIPNN
HIPGDHIPDKATVFTDEESYSFESSKFTRTISPPTLGTLRSCFSWSGGLGDFSRTPSP
SPSTALQQFRRKSDSPTSLPENNMSDVSQLKSEESSDDESHPLREGACSSQSQESGEF
SLQSSNASKLSQCSSKDSDSEESDCNIKLLDSQSDQTSKLCLSHFSKKDTPLRNKVPG
LYKSSSADSLSTTKIKPLGPARASGLSKKPASIQKRKHHNAENKPGLQIKLNELWKNF
GFKKDSEKLPPCKKPLSPVRDNIQLTPEAEEDIFNKPECGRVQRAIFQ"
BASE COUNT 1021 a 644 c 740 g 833 t
ORIGIN
1 gcgttgccgg ccgtgggtgc tctggccaca gtgagttagg ggcgtcggag cgggtttctc
61 caaccgcaat cggctccgct caaggggagg aggagagtcc cttctcggaa ggcctaagga
121 aacgtgtcgt ctggaatggg cttgggggcc acgcctgcac atctccgcga gacagaggga
181 taaagtgaag atggtgctgt tattgttacc tcgagtgcca catgcgacct ctgagatatg
241 tacacagtca ttcttactat cgcactcagc cattcttact acgctaaaga agaaataatt
301 attcgaggat atttgcctgg cccagaagaa acttatgtaa atttcatgaa ctattatatc
361 cgttttcctc ggagtgagag aaaactcttt ttagatatca tctgagagaa ctagtgaatc
421 ccagtcactg agtggagttg agagtctaag aacctctgaa atttgagaac tgctggacca
481 gagcctttag agctctgata aggtgtcaac agggtagtta atttggcacc atggggatac
541 agggattgct acaatttatc aaagaagctt cagaacccat ccatgtgagg aagtataaag
601 ggcaggtagt agctgtggat acatattgct ggcttcacaa aggagctatt gcttgtgctg
661 aaaaactagc caaaggtgaa cctactgata ggtatgtagg attttgtatg aaatttgtaa
721 atatgttact atctcatggg atcaagccta ttctcgtatt tgatggatgt actttacctt
781 ctaaaaagga agtagagaga tctagaagag aaagacgaca agccaatctt cttaagggaa
841 agcaacttct tcgtgagggg aaagtctcgg aagctcgaga gtgtttcacc cggtctatca
901 atatcacaca tgccatggcc cacaaagtaa ttaaagctgc ccggtctcag ggggtagatt
961 gcctcgtggc tccctatgaa gctgatgcgc agttggccta tcttaacaaa gcgggaattg
1021 tgcaagccat aattacagag gactcggatc tcctagcttt tggctgtaaa aaggtaattt
1081 taaagatgga ccagtttgga aatggacttg aaattgatca agctcggcta ggaatgtgca
1141 gacagcttgg ggatgtattc acggaagaga agtttcgtta catgtgtatt ctttcaggtt
1201 gtgactacct gtcatcactg cgtgggattg gattagcaaa ggcatgcaaa gtcctaagac
1261 tagccaataa tccagatata gtaaaggtta tcaagaaaat tggacattat ctcaagatga
1321 atatcacggt accagaggat tacatcaacg ggtttattcg ggccaacaat accttcctct
1381 atcagctagt ttttgatccc atcaaaagga aacttattcc tctgaacgcc tatgaagatg
1441 atgttgatcc tgaaacacta agctacgctg ggcaatatgt tgatgattcc atagctcttc
1501 aaatagcact tggaaataaa gatataaata cttttgaaca gatcgatgac tacaatccag
1561 acactgctat gcctgcccat tcaagaagtc atagttggga tgacaaaaca tgtcaaaagt
1621 cagctaatgt tagcagcatt tggcatagga attactctcc cagaccagag tcgggtactg
1681 tttcagatgc cccacaattg aaggaaaatc caagtactgt gggagtggaa cgagtgatta
1741 gtactaaagg gttaaatctc ccaaggaaat catccattgt gaaaagacca agaagtgcag
1801 agctgtcaga agatgacctg ttgagtcagt attctctttc atttacgaag aagaccaaga
1861 aaaatagctc tgaaggcaat aaatcattga gcttttctga agtgtttgtg cctgacctgg
1921 taaatggacc tactaacaaa aagagtgtaa gcactccacc taggacgaga aataaatttg
1981 caacattttt acaaaggaaa aatgaagaaa gtggtgcagt tgtggttcca gggaccagaa
2041 gcaggttttt ttgcagttca gattctactg actgtgtatc aaacaaagtg agcatccagc
2101 ctctggatga aactgctgtc acagataaag agaacaatct gcatgaatca gagtatggag
2161 accaagaagg caagagactg gttgacacag atgtagcacg taattcaagt gatgacattc
2221 cgaataatca tattccaggt gatcatattc cagacaaggc aacagtgttt acagatgaag
2281 agtcctactc ttttgagagc agcaaattta caaggaccat ttcaccaccc actttgggaa
2341 cactaagaag ttgttttagt tggtctggag gtcttggaga tttttcaaga acgccgagcc
2401 cctctccaag cacagcattg cagcagttcc gaagaaagag cgattccccc acctctttgc
2461 ctgagaataa tatgtctgat gtgtcgcagt taaagagcga ggagtccagt gacgatgagt
2521 ctcatccctt acgagaaggg gcatgttctt cacagtccca ggaaagtgga gaattctcac
2581 tgcagagttc aaatgcatca aagctttctc agtgctctag taaggactct gattcagagg
2641 aatctgattg caatattaag ttacttgaca gtcaaagtga ccagacctcc aagctatgtt
2701 tatctcattt ctcaaaaaaa gacacacctc taaggaacaa ggttcctggg ctatataagt
2761 ccagttctgc agactctctt tctacaacca agatcaaacc tctaggacct gccagagcca
2821 gtgggctgag caagaagccg gcaagcatcc agaagagaaa gcatcataat gccgagaaca
2881 agccggggtt acagatcaaa ctcaatgagc tctggaaaaa ctttggattt aaaaaagatt
2941 ctgaaaagct tcctccttgt aagaaacccc tgtccccagt cagagataac atccaactaa
3001 ctccagaagc ggaagaggat atatttaaca aacctgaatg tggccgtgtt caaagagcaa
3061 tattccagta aatgcagact gctgcaaagc ttttgcctgc aagagaatct gatcaatttg
3121 aagtccctgt ttgggaatga ggcacttatc agcatgaaga attttttctc attctgtgcc
3181 attttaaaaa tagaatacat tttgtatatt gactttaaaa aaaaaaaaaa aaaaaaaa
//