LOCUS BC007230 2007 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens coagulation factor C homolog, cochlin (Limulus
polyphemus), mRNA (cDNA clone MGC:15268 IMAGE:2824361), complete
cds.
ACCESSION BC007230
VERSION BC007230.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2007)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2007)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (01-MAY-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Steven Jones, Jennifer Asano, Ian Bosdet, Yaron Butterfield,
Susanna Chan, Readman Chiu, Chris Fjell, Erin Garland, Ran Guin,
Letticia Hsiao, Martin Krzywinski, Reta Kutsche, Oliver Lee, Soo
Sen Lee, Victor Ling, Carrie Mathewson, Candice McLeavy, Steven
Ness, Pawan Pandoh, Anna-Liisa Prabhu, Parvaneh Saeedi, Jacqueline
Schein, Duane Smailus, Michael Smith, Lorraine Spence, Jeff Stott,
Michael Thorne, Miranada Tsai, Natasja van den Bosch, Jill Vardy,
George Yang, Scott Zuyderduyn, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 22 Row: a Column: 14
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 4758021.
FEATURES Location/Qualifiers
source 1..2007
/db_xref="H-InvDB:HIT000033085"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:15268 IMAGE:2824361"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2007
/gene="COCH"
/gene_synonym="COCH-5B2"
/gene_synonym="COCH5B2"
/gene_synonym="DFNA31"
/gene_synonym="DFNA9"
/db_xref="GeneID:1690"
/db_xref="MIM:603196"
CDS 368..1852
/gene="COCH"
/gene_synonym="COCH-5B2"
/gene_synonym="COCH5B2"
/gene_synonym="DFNA31"
/gene_synonym="DFNA9"
/codon_start=1
/product="COCH protein"
/protein_id="AAH07230.1"
/db_xref="GeneID:1690"
/db_xref="MIM:603196"
/translation="MSAAWIPALGLGVCLLLLPGPAGSEGAAPIAITCFTRGLDIRKE
KADVLCPGGCPLEEFSVYGNIVYASVSSICGAAVHRGVISNSGGPVRVYSLPGRENYS
SVDANGIQSQMLSRWSASFTVTKGKSSTQEATGQAVSTAHPPTGKRLKKTPEKKTGNK
DCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEFY
LKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDG
WPSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMP
NWFGTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSN
IAKTFEISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAI
SFTVRNVFGPIRESPNKNFLVIVTDGQSYDDVQGPAAAAHDAAK"
misc_feature 461..730
/gene="COCH"
/gene_synonym="COCH-5B2"
/gene_synonym="COCH5B2"
/gene_synonym="DFNA31"
/gene_synonym="DFNA9"
/note="LCCL; Region: LCCL domain"
/db_xref="CDD:pfam03815"
misc_feature 860..1291
/gene="COCH"
/gene_synonym="COCH-5B2"
/gene_synonym="COCH5B2"
/gene_synonym="DFNA31"
/gene_synonym="DFNA9"
/note="vwa; Region: von Willebrand factor type A domain"
/db_xref="CDD:pfam00092"
misc_feature 1466..1813
/gene="COCH"
/gene_synonym="COCH-5B2"
/gene_synonym="COCH5B2"
/gene_synonym="DFNA31"
/gene_synonym="DFNA9"
/note="vwa; Region: von Willebrand factor type A domain"
/db_xref="CDD:pfam00092"
BASE COUNT 519 a 486 c 520 g 482 t
ORIGIN
1 gccgggtgga tctcgagcag gtgcggagcc ccgggcggcg ggcgcgggtg cgagggatcc
61 ctgacgcctc tgtccctgtt tctttgtcgc tcccagcctg tctgtcgtcg ttttggcgcc
121 cccgcctccc cgcggtgcgg ggttgcacac cgatcctggg cttcgctcga tttgccgccg
181 aggcgcctcc cagacctaga ggggcgctgg cctggagcag cgggtcgtct gtgtcctctc
241 tcctctgcgc cgcgcccggg gatccgaagg gtgcggggct ctgaggaggt gacgcgcggg
301 gcctcccgca ccctggcctt gcccgcattc tccctctctc ccaggtgtga gcagcctatc
361 agtcaccatg tccgcagcct ggatcccggc tctcggcctc ggtgtgtgtc tgctgctgct
421 gccggggccc gcgggcagcg agggagccgc tcccattgct atcacatgtt ttaccagagg
481 cttggacatc aggaaagaga aagcagatgt cctctgccca gggggctgcc ctcttgagga
541 attctctgtg tatgggaaca tagtatatgc ttctgtatcg agcatatgtg gggctgctgt
601 ccacagggga gtaatcagca actcaggggg acctgtacga gtctatagcc tacctggtcg
661 agaaaactat tcctcagtag atgccaatgg catccagtct caaatgcttt ctagatggtc
721 tgcttctttc acagtaacta aaggcaaaag tagtacacag gaggccacag gacaagcagt
781 gtccacagca catccaccaa caggtaaacg actaaagaaa acacccgaga agaaaactgg
841 caataaagat tgtaaagcag acattgcatt tctgattgat ggaagcttta atattgggca
901 gcgccgattt aatttacaga agaattttgt tggaaaagtg gctctaatgt tgggaattgg
961 aacagaagga ccacatgtgg gccttgttca agccagtgaa catcccaaaa tagaatttta
1021 cttgaaaaac tttacatcag ccaaagatgt tttgtttgcc ataaaggaag taggtttcag
1081 agggggtaat tccaatacag gaaaagcctt gaagcatact gctcagaaat tcttcacggt
1141 agatgctgga gtaagaaaag ggatccccaa agtggtggtg gtatttattg atggttggcc
1201 ttctgatgac atcgaggaag caggcattgt ggccagagag tttggtgtca atgtatttat
1261 agtttctgtg gccaagccta tccctgaaga actggggatg gttcaggatg tcacatttgt
1321 tgacaaggct gtctgtcgga ataatggctt cttctcttac cacatgccca actggtttgg
1381 caccacaaaa tacgtaaagc ctctggtaca gaagctgtgc actcatgaac aaatgatgtg
1441 cagcaagacc tgttataact cagtgaacat tgcctttcta attgatggct ccagcagtgt
1501 tggagatagc aatttccgcc tcatgcttga atttgtttcc aacatagcca agacttttga
1561 aatctcggac attggtgcca agatagctgc tgtacagttt acttatgatc agcgcacgga
1621 gttcagtttc actgactata gcaccaaaga gaatgtccta gctgtcatca gaaacatccg
1681 ctatatgagt ggtggaacag ctactggtga tgccatttcc ttcactgtta gaaatgtgtt
1741 tggccctata agggagagcc ccaacaagaa cttcctagta attgtcacag atgggcagtc
1801 ctatgatgat gtccaaggcc ctgcagctgc tgcacatgat gcagcaaaat aagtttaaaa
1861 gggaatctgt ggcattcaac cgataaacag aagatcacta agagatgaaa aaaagctact
1921 cttggagctc acttccccca acaagagcac cacattccta acccctaagg cagcacacag
1981 agtccaaaaa aaaaaaaaaa aaaaaaa
//