LOCUS BC006491 1718 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens myelin protein zero, mRNA (cDNA clone MGC:10453
IMAGE:3926008), complete cds.
ACCESSION BC006491
VERSION BC006491.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1718)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1718)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (17-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Nov 6, 2003 this sequence version replaced BC006491.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC/DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Institute for Systems Biology
http://www.systemsbiology.org
contact: amadan@systemsbiology.org
Anup Madan, Jessica Fahey, Erin Helton, Mark Ketteman, Anuradha
Madan, Stephanie Rodrigues, Amy Sanchez and Michelle Whiting
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 14 Row: n Column: 2
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 39725669
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..1718
/db_xref="H-InvDB:HIT000032872"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:10453 IMAGE:3926008"
/tissue_type="Skin, melanotic melanoma."
/clone_lib="NIH_MGC_20"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1718
/gene="MPZ"
/gene_synonym="CHM"
/gene_synonym="CMT2I"
/gene_synonym="CMT2J"
/gene_synonym="CMT4E"
/gene_synonym="CMTDI3"
/gene_synonym="DSS"
/gene_synonym="HMSNIB"
/gene_synonym="MPP"
/gene_synonym="P0"
/db_xref="GeneID:4359"
/db_xref="HGNC:HGNC:7225"
/db_xref="MIM:159440"
CDS 20..796
/gene="MPZ"
/gene_synonym="CHM"
/gene_synonym="CMT2I"
/gene_synonym="CMT2J"
/gene_synonym="CMT4E"
/gene_synonym="CMTDI3"
/gene_synonym="DSS"
/gene_synonym="HMSNIB"
/gene_synonym="MPP"
/gene_synonym="P0"
/codon_start=1
/product="MPZ protein"
/protein_id="AAH06491.1"
/db_xref="GeneID:4359"
/db_xref="HGNC:HGNC:7225"
/db_xref="MIM:159440"
/translation="MLRAPAPAPAMAPGAPSSSPSPILAVLLFSSLVLSPAQAIVVYT
DREVHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYIDEV
GTFKERIQWVGDPRWKDGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEKV
PTRYGVVLGAVIGGVLGVVLLLLLLFYVVRYCWLRRQAALQRRLSAMEKGKLHKPGKD
ASKRGRQTPVLYAMLDHSRSTKAVSEKKAKGLGESRKDKK"
BASE COUNT 406 a 471 c 462 g 379 t
ORIGIN
1 cactttctca accccacaga tgctccgggc ccctgcccct gccccagcta tggctcctgg
61 ggctccctca tccagcccca gccctatcct ggctgtgctg ctcttctctt ctttggtgct
121 gtccccggcc caggccatcg tggtttacac cgacagggag gtccatggtg ctgtgggctc
181 ccgggtgacc ctgcactgct ccttctggtc cagtgagtgg gtctcagatg acatctcctt
241 cacctggcgc taccagcccg aagggggcag agatgccatt tcgatcttcc actatgccaa
301 gggacaaccc tacattgacg aggtggggac cttcaaagag cgcatccagt gggtagggga
361 ccctcgctgg aaggatggct ccattgtcat acacaaccta gactacagtg acaatggcac
421 gttcacttgt gacgtcaaaa accctccaga catagtgggc aagacctctc aggtcacgct
481 gtatgtcttt gaaaaagtgc caactaggta cggggtcgtt ctgggagctg tgatcggggg
541 tgtcctcggg gtggtgctgt tgctgctgct gcttttctac gtggttcggt actgctggct
601 acgcaggcag gcggccctgc agaggaggct cagtgctatg gagaagggga aattgcacaa
661 gccaggaaag gacgcgtcga agcgcgggcg gcagacgcca gtgctgtatg caatgctgga
721 ccacagcaga agcaccaaag ctgtcagtga gaagaaggcc aaggggctgg gggagtctcg
781 caaggataag aaatagcggt tagcgggccg ggcgggggat cgggggttag gggtggagtc
841 cgccaaaggc ccaaaggtga tggtcatcga gatggagcta cgaaaggatg agcagagccc
901 ggagctccgg cctgctgtca agtcccccag cagaaccagc ctcaaaaacg ccctcaagaa
961 catgatgggc ctgaactcgg acaagtgatc gccacccccc caccccaggc cctgccagag
1021 cagggggacc taggctcctc ttacccccgt ctaggtgctt tccctctttg ctcccccgcc
1081 ctgccctgcc ctcacctccc tttgagatgt aagtttcatt ccagaattca ttccccagct
1141 ccatactctg tccccccagc taatacccag agcacccaga tcagactctc cttcagggtt
1201 tatttaggtt attatttttt attttttaat ccattctttg tttgtttacc tgtgctcatc
1261 ctctgccctt acacccatga ctgaggacca atgacgtcat gtggcttttg caattcacgc
1321 cccccttaag tccttaatga agagccagcc caagtagagg ggcccctgat cctcacactt
1381 cagtatagca ttggttcccc ctgaccactt tggagcactg ttctgggact ccaggtcttg
1441 aggagagaga cagagagaga gaatggatcc tcataggtca gggagtgggg gagggggcaa
1501 atgagcctta agaaatggtt tttaaacaac caaacaaaaa gcaggaaaaa caaatgggaa
1561 atgggggggc gggggggagg aagaggctgc actgcagcca caggggattc ttaggatttt
1621 tctacattct gtatatttct tctcaaacct ccaaatgtcc ttaaatgttt aataaacact
1681 gacatttcca gaaaaaaaaa aaaaaaaaaa aaaaaaaa
//