LOCUS BC006468 1639 bp mRNA linear HUM 08-FEB-2007
DEFINITION Homo sapiens tubulin, alpha 1a, mRNA (cDNA clone MGC:2321
IMAGE:3528520), complete cds.
ACCESSION BC006468
VERSION BC006468.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1639)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1639)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (09-APR-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 8 Row: o Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 17986282.
FEATURES Location/Qualifiers
source 1..1639
/db_xref="H-InvDB:HIT000032854"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:2321 IMAGE:3528520"
/tissue_type="Muscle, rhabdomyosarcoma"
/clone_lib="NIH_MGC_17"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1639
/gene="TUBA1A"
/gene_synonym="B-ALPHA-1"
/gene_synonym="TUBA3"
/db_xref="GeneID:7846"
/db_xref="HGNC:HGNC:20766"
/db_xref="MIM:602529"
CDS 55..1410
/gene="TUBA1A"
/gene_synonym="B-ALPHA-1"
/gene_synonym="TUBA3"
/codon_start=1
/product="tubulin, alpha 1a"
/protein_id="AAH06468.1"
/db_xref="GeneID:7846"
/db_xref="HGNC:HGNC:20766"
/db_xref="MIM:602529"
/translation="MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGG
GDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANN
YARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVD
YGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLD
IERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVI
SAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAT
IKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLD
HKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEE
Y"
BASE COUNT 401 a 420 c 411 g 407 t
ORIGIN
1 acaacctctc ctcttcgtct ccgccatcag ctcggcagtc gcgaagcagc aaccatgcgt
61 gagtgcatct ccatccacgt tggccaggct ggtgtccaga ttggcaatgc ctgctgggag
121 ctctactgcc tggaacacgg catccagccc gatggccaga tgccaagtga caagaccatt
181 gggggaggag atgattcctt caacaccttc ttcagtgaga cgggggctgg caagcatgtg
241 ccccgggcag tgtttgtaga cttggaaccc acagtcattg atgaagttcg cactggcacc
301 taccgccagc tcttccaccc tgagcaactt atcacaggca aagaagatgc tgccaataac
361 tatgcccgag ggcactacac cattggcaag gagatcattg acctcgtgtt ggaccgaatt
421 cgcaagctgg ccgaccagtg cacgggtctc cagggcttct tggttttcca cagctttggt
481 gggggaactg gttctgggtt cacctcgctg ctcatggaac gtctctcagt tgattatggc
541 aagaagtcca agctggagtt ctctatttac ccggcgcccc aggtttccac agctgtagtt
601 gagccctaca actccatcct caccacccac accaccctgg agcactctga ttgtgccttc
661 atggtagaca atgaggccat ctatgacatc tgtcgtagaa acctcgatat tgagcgtcca
721 acctatacta acctgaatag gttaataggt caaattgtgt cctccatcac tgcttccctg
781 agatttgatg gagccctgaa tgttgacctg acagaattcc agaccaacct ggtgccctat
841 ccccgcatcc acttccctct ggccacatat gcccctgtca tctctgctga gaaagcctac
901 catgaacagc tttctgtagc agagatcacc aatgcttgct ttgagccagc caaccagatg
961 gtgaaatgtg accctcgcca tggtaaatac atggcttgct gcctgttgta ccgtggtgac
1021 gtggttccca aagatgtcaa tgctgccatt gccaccatca agaccaagcg taccatccag
1081 tttgtggatt ggtgccccac tggcttcaag gttggcatca actaccagcc tcccactgtg
1141 gtgcctggtg gagacctggc caaggtacag agagctgtgt gcatgctgag caacaccaca
1201 gccattgctg aggcctgggc tcgcctggac cacaagtttg acctgatgta tgccaaacgt
1261 gcctttgttc actggtacgt tggggagggg atggaggaag gtgagttttc agaggcccgt
1321 gaggacatgg ctgcccttga gaaggattat gaggaggttg gtgtggattc tgttgaagga
1381 gagggtgagg aagaaggaga ggaatactaa agttaaaacg tcacaaaggt gctgctttta
1441 cagggaagct tattctgttt taaacattga aaagttgtgg tctgatcagt taatttgtat
1501 gtagcagtgt atgctctcat atacaattac tgacctatgc tctaaaacat gaatgctttg
1561 ttacagaccc aagctgtcca tttctgtgat gggttttgaa taaagtattc cctgtcttaa
1621 aaaaaaaaaa aaaaaaaaa
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